ID A7ANP3_BABBO Unreviewed; 388 AA.
AC A7ANP3;
DT 11-SEP-2007, integrated into UniProtKB/TrEMBL.
DT 11-SEP-2007, sequence version 1.
DT 24-JAN-2024, entry version 48.
DE RecName: Full=Ribosome biogenesis protein NOP53 {ECO:0000256|ARBA:ARBA00018339};
GN ORFNames=BBOV_III006160 {ECO:0000313|EMBL:EDO08177.1};
OS Babesia bovis.
OC Eukaryota; Sar; Alveolata; Apicomplexa; Aconoidasida; Piroplasmida;
OC Babesiidae; Babesia.
OX NCBI_TaxID=5865 {ECO:0000313|EMBL:EDO08177.1, ECO:0000313|Proteomes:UP000002173};
RN [1] {ECO:0000313|EMBL:EDO08177.1, ECO:0000313|Proteomes:UP000002173}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=T2Bo {ECO:0000313|EMBL:EDO08177.1};
RX PubMed=17953480; DOI=10.1371/journal.ppat.0030148;
RA Brayton K.A., Lau A.O.T., Herndon D.R., Hannick L., Kappmeyer L.S.,
RA Berens S.J., Bidwell S.L., Brown W.C., Crabtree J., Fadrosh D.,
RA Feldblum T., Forberger H.A., Haas B.J., Howell J.M., Khouri H., Koo H.,
RA Mann D.J., Norimine J., Paulsen I.T., Radune D., Ren Q., Smith R.K. Jr.,
RA Suarez C.E., White O., Wortman J.R., Knowles D.P. Jr., McElwain T.F.,
RA Nene V.M.;
RT "Genome sequence of Babesia bovis and comparative analysis of apicomplexan
RT hemoprotozoa.";
RL PLoS Pathog. 3:1401-1413(2007).
RN [2] {ECO:0000313|Proteomes:UP000002173}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=33294524; DOI=10.1016/j.dib.2020.106533;
RA Ueti M.W., Johnson W.C., Kappmeyer L.S., Herndon D.R., Mousel M.R.,
RA Reif K.E., Taus N.S., Ifeonu O.O., Silva J.C., Suarez C.E., Brayton K.A.;
RT "Transcriptome dataset of Babesia bovis life stages within vertebrate and
RT invertebrate hosts.";
RL Data Brief 33:106533-106533(2020).
RN [3] {ECO:0000313|Proteomes:UP000002173}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=33069745;
RA Ueti M.W., Johnson W.C., Kappmeyer L.S., Herndon D.R., Mousel M.R.,
RA Reif K.E., Taus N.S., Ifeonu O.O., Silva J.C., Suarez C.E., Brayton K.A.;
RT "Comparative analysis of gene expression between Babesia bovis blood stages
RT and kinetes allowed by improved genome annotation.";
RL Int. J. Parasitol. 51:123-136(2021).
CC -!- SUBCELLULAR LOCATION: Nucleus, nucleolus
CC {ECO:0000256|ARBA:ARBA00004604}. Nucleus, nucleoplasm
CC {ECO:0000256|ARBA:ARBA00004642}.
CC -!- SIMILARITY: Belongs to the NOP53 family.
CC {ECO:0000256|ARBA:ARBA00008838}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EDO08177.1}.
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DR EMBL; AAXT01000001; EDO08177.1; -; Genomic_DNA.
DR RefSeq; XP_001611745.1; XM_001611695.1.
DR AlphaFoldDB; A7ANP3; -.
DR STRING; 5865.A7ANP3; -.
DR EnsemblProtists; EDO08177; EDO08177; BBOV_III006160.
DR GeneID; 5479996; -.
DR KEGG; bbo:BBOV_III006160; -.
DR VEuPathDB; PiroplasmaDB:BBOV_III006160; -.
DR eggNOG; ENOG502SEKX; Eukaryota.
DR InParanoid; A7ANP3; -.
DR OMA; KYHERAR; -.
DR Proteomes; UP000002173; Unassembled WGS sequence.
DR GO; GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.
DR GO; GO:0005654; C:nucleoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0042254; P:ribosome biogenesis; IEA:UniProtKB-KW.
DR InterPro; IPR011687; Nop53/GLTSCR2.
DR PANTHER; PTHR14211; GLIOMA SUPPRESSOR CANDIDATE REGION GENE 2; 1.
DR PANTHER; PTHR14211:SF7; RIBOSOME BIOGENESIS PROTEIN NOP53; 1.
DR Pfam; PF07767; Nop53; 1.
PE 3: Inferred from homology;
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000002173};
KW Ribosome biogenesis {ECO:0000256|ARBA:ARBA00022517}.
FT REGION 217..249
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 233..247
FT /note="Basic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 388 AA; 43949 MW; B4C7F12B8052606C CRC64;
MAPKKKWKRI DVSSVQESLF ESNIAQNVAK GGLSEAMVID TIGEAPSRRL AKKIKSQRHG
DPIASRGTVE RARLQKLVSR LKSERARMDI EENAPQGNER VIDDIWGDNA EPAAMLRPSM
PTLAKVIPAV AAPHSGQSYN PSPEAREELI NKAYESLPQE EDFSDEPLTD MIRECLPNVD
VDNLTFRQKQ VLGNLIIQDK LDESSIMEAL AAADQEEVSE EEMDNTATAN KRRVTTKKTR
AKRNREKLHK ASIAQALMRK RIKRLVHDID HFKDTKHEND PLEIEEAKKE RLRKYLQDLV
KGRITPKFGN KVYRVDPPEV PLSDEVTSSL RQLASPSEAS VRCVVDSIYR RGLVPAPPVI
DEQYRSKARS KLLRRTRKFK SKLLHGTT
//
