ID A7ARM3_BABBO Unreviewed; 894 AA.
AC A7ARM3;
DT 11-SEP-2007, integrated into UniProtKB/TrEMBL.
DT 11-SEP-2007, sequence version 1.
DT 27-MAR-2024, entry version 89.
DE SubName: Full=SNF2 helicase, putative {ECO:0000313|EMBL:EDO07192.1};
DE EC=3.6.1.- {ECO:0000313|EMBL:EDO07192.1};
GN ORFNames=BBOV_IV008380 {ECO:0000313|EMBL:EDO07192.1};
OS Babesia bovis.
OC Eukaryota; Sar; Alveolata; Apicomplexa; Aconoidasida; Piroplasmida;
OC Babesiidae; Babesia.
OX NCBI_TaxID=5865 {ECO:0000313|EMBL:EDO07192.1};
RN [1] {ECO:0000313|EMBL:EDO07192.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=T2Bo {ECO:0000313|EMBL:EDO07192.1};
RX PubMed=17953480; DOI=10.1371/journal.ppat.0030148;
RA Brayton K.A., Lau A.O.T., Herndon D.R., Hannick L., Kappmeyer L.S.,
RA Berens S.J., Bidwell S.L., Brown W.C., Crabtree J., Fadrosh D.,
RA Feldblum T., Forberger H.A., Haas B.J., Howell J.M., Khouri H., Koo H.,
RA Mann D.J., Norimine J., Paulsen I.T., Radune D., Ren Q., Smith R.K. Jr.,
RA Suarez C.E., White O., Wortman J.R., Knowles D.P. Jr., McElwain T.F.,
RA Nene V.M.;
RT "Genome sequence of Babesia bovis and comparative analysis of apicomplexan
RT hemoprotozoa.";
RL PLoS Pathog. 3:1401-1413(2007).
RN [2] {ECO:0000313|EMBL:EDO07192.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=T2Bo {ECO:0000313|EMBL:EDO07192.1};
RA Nene V.;
RL Submitted (AUG-2007) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the SNF2/RAD54 helicase family. ISWI subfamily.
CC {ECO:0000256|ARBA:ARBA00009687}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EDO07192.1}.
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DR EMBL; AAXT01000002; EDO07192.1; -; Genomic_DNA.
DR RefSeq; XP_001610760.1; XM_001610710.1.
DR AlphaFoldDB; A7ARM3; -.
DR STRING; 5865.A7ARM3; -.
DR EnsemblProtists; EDO07192; EDO07192; BBOV_IV008380.
DR VEuPathDB; PiroplasmaDB:BBOV_IV008370; -.
DR eggNOG; KOG0385; Eukaryota.
DR InParanoid; A7ARM3; -.
DR GO; GO:0005634; C:nucleus; IEA:InterPro.
DR GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR GO; GO:0140658; F:ATP-dependent chromatin remodeler activity; IEA:InterPro.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR GO; GO:0004386; F:helicase activity; IEA:UniProtKB-KW.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR CDD; cd00167; SANT; 1.
DR CDD; cd18793; SF2_C_SNF; 1.
DR Gene3D; 1.10.10.60; Homeodomain-like; 2.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 3.40.50.10810; Tandem AAA-ATPase domain; 1.
DR InterPro; IPR002464; DNA/RNA_helicase_DEAH_CS.
DR InterPro; IPR014001; Helicase_ATP-bd.
DR InterPro; IPR001650; Helicase_C.
DR InterPro; IPR009057; Homeobox-like_sf.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR001005; SANT/Myb.
DR InterPro; IPR017884; SANT_dom.
DR InterPro; IPR015195; SLIDE.
DR InterPro; IPR038718; SNF2-like_sf.
DR InterPro; IPR049730; SNF2/RAD54-like_C.
DR InterPro; IPR000330; SNF2_N.
DR PANTHER; PTHR10799:SF879; CHROMATIN-REMODELING COMPLEX ATPASE CHAIN ISWI; 1.
DR PANTHER; PTHR10799; SNF2/RAD54 HELICASE FAMILY; 1.
DR Pfam; PF00271; Helicase_C; 1.
DR Pfam; PF09111; SLIDE; 1.
DR Pfam; PF00176; SNF2-rel_dom; 1.
DR SMART; SM00487; DEXDc; 1.
DR SMART; SM00490; HELICc; 1.
DR SMART; SM00717; SANT; 2.
DR SUPFAM; SSF46689; Homeodomain-like; 2.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 2.
DR PROSITE; PS00690; DEAH_ATP_HELICASE; 1.
DR PROSITE; PS51192; HELICASE_ATP_BIND_1; 1.
DR PROSITE; PS51194; HELICASE_CTER; 1.
DR PROSITE; PS51293; SANT; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Helicase {ECO:0000313|EMBL:EDO07192.1};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000313|EMBL:EDO07192.1};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741}.
FT DOMAIN 98..263
FT /note="Helicase ATP-binding"
FT /evidence="ECO:0000259|PROSITE:PS51192"
FT DOMAIN 405..561
FT /note="Helicase C-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51194"
FT DOMAIN 723..775
FT /note="SANT"
FT /evidence="ECO:0000259|PROSITE:PS51293"
FT REGION 1..26
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 58..79
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 894 AA; 102785 MW; B510E448681498B2 CRC64;
MANGDHIASG GDGTKPSSDI PLSPPTAVSN ASLLHKLLHE DHFVDDILAN SRKTFSKGAS
SSKASAANRK KNAEVTQQPK NLVGTAKPYQ LEGLRWLVGL YDRNMNGILA DEMGLGKTFQ
TISLLAYLKE SRGIDGLHLV IAPKSTIGNW INEINRFCPD LRVLKFIGNK EERSYMVSHE
LDSSKYDVIV TSYETCCKAK NALSKLQFHY IIIDEAHRIK NEESKLSEVV RVFHTEYRLL
ITGTPLQNNL KELWALLNFL FPEVFASSEE FEAEFDLVGP KDLSQEERES RNLRIVARLH
EILRPFMLRR SKKDVLTDMP PKTELLLMIP LSAMQKRLYK DLLRRTVPDL GAEDSHSSVV
KVQLLNLAMQ LRKACNHPYL FEGWEDRDAD PFGEHLVENA GKLNVVDKLL RRLLKANSRI
LIFSQMARML DILEDYCRMR GYSYFRIDGN TSGEERDDQI SSFNDPNSEV SIFLLSTRAG
GLGINLATAD VVILYDSDWN PQVDLQAIDR AHRIGQSKTV HVYRLVHEYT IEEKIIERAT
IKLQLDSAVI QSGRMGQKEL LEMVQFGAGH VFKAGDEEIT EADLDVILSK GLERATMLND
KLKAHTGKAL LDFSTNNSSQ QLYDYETLEA TNKEDQVAWD ELVALRVQDE VLHERDIRRR
MRMTAARLAE ADAARFARFN KHPPFQDWQF FDKAEISRID QLEQEQGEID EELRAKRDQL
LSEGFADWNK RHFAAFIRAN AAYSRYDIES IANSIKSKSP EEVKRYSKVF WEKYKQMSDW
GKYIKRIEQG EESLLKRNIL HQMIVAKQKL IKCPWVNTDL ALTSHRGKCP YTEEEDRWIL
NVVAILGYDQ WDDIAELSRL DPRWQFDSFL HTRSPNDFMK RADYIIKYIA RERG
//
