ID A7AU51_BABBO Unreviewed; 297 AA.
AC A7AU51;
DT 11-SEP-2007, integrated into UniProtKB/TrEMBL.
DT 11-SEP-2007, sequence version 1.
DT 27-MAR-2024, entry version 42.
DE RecName: Full=Copper transport protein {ECO:0000256|RuleBase:RU367022};
GN ORFNames=BBOV_II005100 {ECO:0000313|EMBL:EDO06462.1};
OS Babesia bovis.
OC Eukaryota; Sar; Alveolata; Apicomplexa; Aconoidasida; Piroplasmida;
OC Babesiidae; Babesia.
OX NCBI_TaxID=5865 {ECO:0000313|EMBL:EDO06462.1, ECO:0000313|Proteomes:UP000002173};
RN [1] {ECO:0000313|EMBL:EDO06462.1, ECO:0000313|Proteomes:UP000002173}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=T2Bo {ECO:0000313|EMBL:EDO06462.1};
RX PubMed=17953480; DOI=10.1371/journal.ppat.0030148;
RA Brayton K.A., Lau A.O.T., Herndon D.R., Hannick L., Kappmeyer L.S.,
RA Berens S.J., Bidwell S.L., Brown W.C., Crabtree J., Fadrosh D.,
RA Feldblum T., Forberger H.A., Haas B.J., Howell J.M., Khouri H., Koo H.,
RA Mann D.J., Norimine J., Paulsen I.T., Radune D., Ren Q., Smith R.K. Jr.,
RA Suarez C.E., White O., Wortman J.R., Knowles D.P. Jr., McElwain T.F.,
RA Nene V.M.;
RT "Genome sequence of Babesia bovis and comparative analysis of apicomplexan
RT hemoprotozoa.";
RL PLoS Pathog. 3:1401-1413(2007).
RN [2] {ECO:0000313|Proteomes:UP000002173}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=33294524; DOI=10.1016/j.dib.2020.106533;
RA Ueti M.W., Johnson W.C., Kappmeyer L.S., Herndon D.R., Mousel M.R.,
RA Reif K.E., Taus N.S., Ifeonu O.O., Silva J.C., Suarez C.E., Brayton K.A.;
RT "Transcriptome dataset of Babesia bovis life stages within vertebrate and
RT invertebrate hosts.";
RL Data Brief 33:106533-106533(2020).
RN [3] {ECO:0000313|Proteomes:UP000002173}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=33069745;
RA Ueti M.W., Johnson W.C., Kappmeyer L.S., Herndon D.R., Mousel M.R.,
RA Reif K.E., Taus N.S., Ifeonu O.O., Silva J.C., Suarez C.E., Brayton K.A.;
RT "Comparative analysis of gene expression between Babesia bovis blood stages
RT and kinetes allowed by improved genome annotation.";
RL Int. J. Parasitol. 51:123-136(2021).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141,
CC ECO:0000256|RuleBase:RU367022}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141, ECO:0000256|RuleBase:RU367022}.
CC -!- SIMILARITY: Belongs to the copper transporter (Ctr) (TC 1.A.56) family.
CC SLC31A subfamily. {ECO:0000256|ARBA:ARBA00006921,
CC ECO:0000256|RuleBase:RU367022}.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|RuleBase:RU367022}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EDO06462.1}.
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DR EMBL; AAXT01000003; EDO06462.1; -; Genomic_DNA.
DR RefSeq; XP_001610030.1; XM_001609980.1.
DR AlphaFoldDB; A7AU51; -.
DR STRING; 5865.A7AU51; -.
DR EnsemblProtists; EDO06462; EDO06462; BBOV_II005100.
DR GeneID; 5478262; -.
DR KEGG; bbo:BBOV_II005100; -.
DR VEuPathDB; PiroplasmaDB:BBOV_II005100; -.
DR eggNOG; KOG3386; Eukaryota.
DR InParanoid; A7AU51; -.
DR Proteomes; UP000002173; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005375; F:copper ion transmembrane transporter activity; IEA:UniProtKB-UniRule.
DR InterPro; IPR007274; Cop_transporter.
DR PANTHER; PTHR12483:SF27; COPPER TRANSPORT PROTEIN; 1.
DR PANTHER; PTHR12483; SOLUTE CARRIER FAMILY 31 COPPER TRANSPORTERS; 1.
DR Pfam; PF04145; Ctr; 1.
PE 3: Inferred from homology;
KW Copper {ECO:0000256|RuleBase:RU367022};
KW Copper transport {ECO:0000256|RuleBase:RU367022};
KW Ion transport {ECO:0000256|RuleBase:RU367022};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|RuleBase:RU367022};
KW Reference proteome {ECO:0000313|Proteomes:UP000002173};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW ECO:0000256|RuleBase:RU367022};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|RuleBase:RU367022}; Transport {ECO:0000256|RuleBase:RU367022}.
FT TRANSMEM 7..27
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU367022"
FT TRANSMEM 188..208
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU367022"
FT TRANSMEM 229..251
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU367022"
FT TRANSMEM 257..278
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU367022"
SQ SEQUENCE 297 AA; 31731 MW; FF386E6916431912 CRC64;
MVCRMTIAFF VSIFGVYISL NCSATLLGGS SLNTSDGVST YNASLGPLSA DRCENAQAPT
HQALQLVLPE EDVESLRIRV NEAFDAERDH LNNGFRASDS TIAGTVSAAP AIFGAGTGCC
SEAKPNPEEH CSTGACPSKV PAAEPAAAAS HCASAESSGS CSMPMYFENT VKTVILFHFW
KTTTGTQYAV SLFFIFVLSL MTVFLKAFRN KLNCALLQRP NGYHPTVKYG IMYILAFVVT
FMDFAMMLVV MTFNVGIVLV VCSAYALGYI FTCCPLGLSE AANGSRCTQE CPADCCC
//
