ID A7AVA4_BABBO Unreviewed; 653 AA.
AC A7AVA4;
DT 11-SEP-2007, integrated into UniProtKB/TrEMBL.
DT 11-SEP-2007, sequence version 1.
DT 24-JAN-2024, entry version 56.
DE SubName: Full=U3 small nucleolar ribonucleoprotein protein, putative {ECO:0000313|EMBL:EDO05730.1};
GN ORFNames=BBOV_IV001330 {ECO:0000313|EMBL:EDO05730.1};
OS Babesia bovis.
OC Eukaryota; Sar; Alveolata; Apicomplexa; Aconoidasida; Piroplasmida;
OC Babesiidae; Babesia.
OX NCBI_TaxID=5865 {ECO:0000313|EMBL:EDO05730.1, ECO:0000313|Proteomes:UP000002173};
RN [1] {ECO:0000313|EMBL:EDO05730.1, ECO:0000313|Proteomes:UP000002173}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=T2Bo {ECO:0000313|EMBL:EDO05730.1};
RX PubMed=17953480; DOI=10.1371/journal.ppat.0030148;
RA Brayton K.A., Lau A.O.T., Herndon D.R., Hannick L., Kappmeyer L.S.,
RA Berens S.J., Bidwell S.L., Brown W.C., Crabtree J., Fadrosh D.,
RA Feldblum T., Forberger H.A., Haas B.J., Howell J.M., Khouri H., Koo H.,
RA Mann D.J., Norimine J., Paulsen I.T., Radune D., Ren Q., Smith R.K. Jr.,
RA Suarez C.E., White O., Wortman J.R., Knowles D.P. Jr., McElwain T.F.,
RA Nene V.M.;
RT "Genome sequence of Babesia bovis and comparative analysis of apicomplexan
RT hemoprotozoa.";
RL PLoS Pathog. 3:1401-1413(2007).
RN [2] {ECO:0000313|Proteomes:UP000002173}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=33294524; DOI=10.1016/j.dib.2020.106533;
RA Ueti M.W., Johnson W.C., Kappmeyer L.S., Herndon D.R., Mousel M.R.,
RA Reif K.E., Taus N.S., Ifeonu O.O., Silva J.C., Suarez C.E., Brayton K.A.;
RT "Transcriptome dataset of Babesia bovis life stages within vertebrate and
RT invertebrate hosts.";
RL Data Brief 33:106533-106533(2020).
RN [3] {ECO:0000313|Proteomes:UP000002173}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=33069745;
RA Ueti M.W., Johnson W.C., Kappmeyer L.S., Herndon D.R., Mousel M.R.,
RA Reif K.E., Taus N.S., Ifeonu O.O., Silva J.C., Suarez C.E., Brayton K.A.;
RT "Comparative analysis of gene expression between Babesia bovis blood stages
RT and kinetes allowed by improved genome annotation.";
RL Int. J. Parasitol. 51:123-136(2021).
CC -!- SUBCELLULAR LOCATION: Nucleus, nucleolus
CC {ECO:0000256|ARBA:ARBA00004604}.
CC -!- SIMILARITY: Belongs to the MPP10 family.
CC {ECO:0000256|ARBA:ARBA00029455}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EDO05730.1}.
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DR EMBL; AAXT01000004; EDO05730.1; -; Genomic_DNA.
DR RefSeq; XP_001609298.1; XM_001609248.1.
DR AlphaFoldDB; A7AVA4; -.
DR STRING; 5865.A7AVA4; -.
DR EnsemblProtists; EDO05730; EDO05730; BBOV_IV001330.
DR GeneID; 5477517; -.
DR KEGG; bbo:BBOV_IV001330; -.
DR VEuPathDB; PiroplasmaDB:BBOV_IV001330; -.
DR eggNOG; KOG2600; Eukaryota.
DR InParanoid; A7AVA4; -.
DR Proteomes; UP000002173; Unassembled WGS sequence.
DR GO; GO:0034457; C:Mpp10 complex; IEA:InterPro.
DR GO; GO:0005732; C:sno(s)RNA-containing ribonucleoprotein complex; IEA:InterPro.
DR GO; GO:0006364; P:rRNA processing; IEA:UniProtKB-KW.
DR InterPro; IPR012173; Mpp10.
DR PANTHER; PTHR17039; U3 SMALL NUCLEOLAR RIBONUCLEOPROTEIN PROTEIN MPP10; 1.
DR PANTHER; PTHR17039:SF0; U3 SMALL NUCLEOLAR RIBONUCLEOPROTEIN PROTEIN MPP10; 1.
DR Pfam; PF04006; Mpp10; 1.
PE 3: Inferred from homology;
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000002173};
KW Ribonucleoprotein {ECO:0000256|ARBA:ARBA00023274,
KW ECO:0000313|EMBL:EDO05730.1};
KW Ribosome biogenesis {ECO:0000256|ARBA:ARBA00022517};
KW rRNA processing {ECO:0000256|ARBA:ARBA00022552}.
FT REGION 131..232
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 319..339
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 620..642
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 171..197
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 199..213
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 321..335
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 653 AA; 74409 MW; D9664C503749C459 CRC64;
MEKSNSEIPD STDACVSPSE LLQRPWTLFD NTKQCESMLR DKLLEFFKGV VLLKRRRIRI
ADEVGKKRST RSAAIKRALA LAKADSKRVY NSASTLGVND LWTYLESELS GDIKLLTEKL
EKVLQTQPRG ILKSGRGDLQ QQGNRNSHIS VDDSPLERGM EDVSSSSESM GESDTEEEDY
DDDQSDEESE PGWETASAED EIDGSKDVGT SDESDYESPD DGLDDTSMDK RDKATKDRFF
KMEEMEEFAN GEIEDEDDFN YFESLGEESD DSKPAVDMMY DDFFKEPSED GDEAEALHCS
RDLEGLDADE REMELLLQRV EEDGESEDEY SDRDESELVD FDHNIDPERE RQMDDVDDDD
DQISQVEKDL IAEKHWSLMG EASARKRARN SLLDLDLELP QNSAFIHAEA AGEMDGVVED
DTMGLEENQD VPIEIIIQQR IKAEVFDNIE RKIAPEDQLE AIERLKQKRN KMNQGAVEID
FNKSKMGLGD VYAQRYQEMF MATDKLDAHK QKLAEDFGKI MFKLDSLCNY HIVPKRVSEA
EKNKNVASIT VEAPINVVPA SRHNDVTDIS EGNKLSRTAK KRKFTNKIKA LLKSGKATVE
DIKRMKQKMV ERNRQKIEDM RSVKATGQTK ERGAREQKPS GRVKIAELMN RRK
//
