ID   A7ELY5_SCLS1            Unreviewed;       694 AA.
AC   A7ELY5;
DT   11-SEP-2007, integrated into UniProtKB/TrEMBL.
DT   11-SEP-2007, sequence version 1.
DT   24-JAN-2024, entry version 81.
DE   RecName: Full=Manganese lipoxygenase {ECO:0000256|ARBA:ARBA00021175};
GN   ORFNames=SS1G_06332 {ECO:0000313|EMBL:EDO03851.1};
OS   Sclerotinia sclerotiorum (strain ATCC 18683 / 1980 / Ss-1) (White mold)
OS   (Whetzelinia sclerotiorum).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Leotiomycetes;
OC   Helotiales; Sclerotiniaceae; Sclerotinia.
OX   NCBI_TaxID=665079 {ECO:0000313|EMBL:EDO03851.1, ECO:0000313|Proteomes:UP000001312};
RN   [1] {ECO:0000313|Proteomes:UP000001312}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 18683 / 1980 / Ss-1 {ECO:0000313|Proteomes:UP000001312};
RX   PubMed=21876677; DOI=.1371/journal.pgen.1002230;
RA   Amselem J., Cuomo C.A., van Kan J.A., Viaud M., Benito E.P., Couloux A.,
RA   Coutinho P.M., de Vries R.P., Dyer P.S., Fillinger S., Fournier E.,
RA   Gout L., Hahn M., Kohn L., Lapalu N., Plummer K.M., Pradier J.M.,
RA   Quevillon E., Sharon A., Simon A., ten Have A., Tudzynski B., Tudzynski P.,
RA   Wincker P., Andrew M., Anthouard V., Beever R.E., Beffa R., Benoit I.,
RA   Bouzid O., Brault B., Chen Z., Choquer M., Collemare J., Cotton P.,
RA   Danchin E.G., Da Silva C., Gautier A., Giraud C., Giraud T., Gonzalez C.,
RA   Grossetete S., Guldener U., Henrissat B., Howlett B.J., Kodira C.,
RA   Kretschmer M., Lappartient A., Leroch M., Levis C., Mauceli E.,
RA   Neuveglise C., Oeser B., Pearson M., Poulain J., Poussereau N.,
RA   Quesneville H., Rascle C., Schumacher J., Segurens B., Sexton A., Silva E.,
RA   Sirven C., Soanes D.M., Talbot N.J., Templeton M., Yandava C., Yarden O.,
RA   Zeng Q., Rollins J.A., Lebrun M.H., Dickman M.;
RT   "Genomic analysis of the necrotrophic fungal pathogens Sclerotinia
RT   sclerotiorum and Botrytis cinerea.";
RL   PLoS Genet. 7:E1002230-E1002230(2011).
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DR   EMBL; CH476628; EDO03851.1; -; Genomic_DNA.
DR   RefSeq; XP_001592093.1; XM_001592043.1.
DR   AlphaFoldDB; A7ELY5; -.
DR   STRING; 665079.A7ELY5; -.
DR   GeneID; 5488580; -.
DR   KEGG; ssl:SS1G_06332; -.
DR   VEuPathDB; FungiDB:sscle_13g092110; -.
DR   InParanoid; A7ELY5; -.
DR   OMA; SYFREAT; -.
DR   OrthoDB; 1050333at2759; -.
DR   Proteomes; UP000001312; Unassembled WGS sequence.
DR   GO; GO:0050584; F:linoleate 11-lipoxygenase activity; IEA:UniProt.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0016702; F:oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen; IBA:GO_Central.
DR   GO; GO:0043651; P:linoleic acid metabolic process; IEA:UniProt.
DR   GO; GO:0034440; P:lipid oxidation; IBA:GO_Central.
DR   Gene3D; 3.10.450.60; -; 1.
DR   InterPro; IPR000907; LipOase.
DR   InterPro; IPR013819; LipOase_C.
DR   InterPro; IPR036226; LipOase_C_sf.
DR   PANTHER; PTHR11771; LIPOXYGENASE; 1.
DR   PANTHER; PTHR11771:SF153; LIPOXYGENASE DOMAIN-CONTAINING PROTEIN; 1.
DR   Pfam; PF00305; Lipoxygenase; 1.
DR   SUPFAM; SSF48484; Lipoxigenase; 1.
DR   PROSITE; PS51393; LIPOXYGENASE_3; 1.
PE   4: Predicted;
KW   Dioxygenase {ECO:0000256|ARBA:ARBA00022964};
KW   Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW   Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW   Reference proteome {ECO:0000313|Proteomes:UP000001312}.
FT   DOMAIN          191..684
FT                   /note="Lipoxygenase"
FT                   /evidence="ECO:0000259|PROSITE:PS51393"
FT   REGION          1..41
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1..31
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   694 AA;  78182 MW;  4A040381CD8BA0AB CRC64;
     MSASQGMNVA NGTNGATRAN EPTARSPENP KMANSTKEKR PNIIRRPIRR LNKNQPKVPG
     IIVATPAEIN EATAKLAQGF EAEKPFIPRR FETQRALYQW ALPGSTSSYP PHLKWIPLDN
     RVGLLKIFNL RRFVDVSVSL LPKIPPEISN LLSGDPYNGT TMAMLEERMI ALNKEQKNVG
     TEPSIGYRKD WYSDAVFAQQ YFTGPNPSSI ALASQIWLDR FKNAVFDQGN KEMHSLLERF
     NSNSFFIQDC SFFHEWAGAS PDATLKFDNG KRFGCASVTL FHLNADGDLH PLAIVLDYKV
     SMEKSVTIFN KRINPKDPKD NEHNDWPWRY AKMCSLVADW THHELTLHLN DCHFVEEASA
     VAAYRSFPSD HIVYKILEPH WFKTLSLNAA ARDTLVPQLI SKINGFTERQ TYDYLLSSYR
     NFNWTGNYAP TSLITRGFPL SSLNDKSDRR FHNYAYGKNM AILWPILFDF VSSMLGTFYT
     GDADVAKDTC VSAWCNEMQS PTGGQMPTFP SIRTLDELTN AITMCIHIAS PQHNAINYLQ
     NYYMSFIPNK PPSLQQPLPG SLSALQKYRE VDVINSLPVN DPTLWIQASQ LPYLISFRVA
     EDQTLSAFAR ELRNATIDPQ GRFAGPGDAA RRTDGVRRAA EKLLQDLDVA ARKFKENSDA
     LTEGTAPHFV MDPGELALLG SISLFALVCW RAFN
//