ID A7EX67_SCLS1 Unreviewed; 883 AA.
AC A7EX67;
DT 11-SEP-2007, integrated into UniProtKB/TrEMBL.
DT 11-SEP-2007, sequence version 1.
DT 08-NOV-2023, entry version 94.
DE RecName: Full=Origin recognition complex subunit 4 {ECO:0000256|ARBA:ARBA00019083};
GN ORFNames=SS1G_09927 {ECO:0000313|EMBL:EDN94059.1};
OS Sclerotinia sclerotiorum (strain ATCC 18683 / 1980 / Ss-1) (White mold)
OS (Whetzelinia sclerotiorum).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Leotiomycetes;
OC Helotiales; Sclerotiniaceae; Sclerotinia.
OX NCBI_TaxID=665079 {ECO:0000313|EMBL:EDN94059.1, ECO:0000313|Proteomes:UP000001312};
RN [1] {ECO:0000313|Proteomes:UP000001312}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 18683 / 1980 / Ss-1 {ECO:0000313|Proteomes:UP000001312};
RX PubMed=21876677; DOI=.1371/journal.pgen.1002230;
RA Amselem J., Cuomo C.A., van Kan J.A., Viaud M., Benito E.P., Couloux A.,
RA Coutinho P.M., de Vries R.P., Dyer P.S., Fillinger S., Fournier E.,
RA Gout L., Hahn M., Kohn L., Lapalu N., Plummer K.M., Pradier J.M.,
RA Quevillon E., Sharon A., Simon A., ten Have A., Tudzynski B., Tudzynski P.,
RA Wincker P., Andrew M., Anthouard V., Beever R.E., Beffa R., Benoit I.,
RA Bouzid O., Brault B., Chen Z., Choquer M., Collemare J., Cotton P.,
RA Danchin E.G., Da Silva C., Gautier A., Giraud C., Giraud T., Gonzalez C.,
RA Grossetete S., Guldener U., Henrissat B., Howlett B.J., Kodira C.,
RA Kretschmer M., Lappartient A., Leroch M., Levis C., Mauceli E.,
RA Neuveglise C., Oeser B., Pearson M., Poulain J., Poussereau N.,
RA Quesneville H., Rascle C., Schumacher J., Segurens B., Sexton A., Silva E.,
RA Sirven C., Soanes D.M., Talbot N.J., Templeton M., Yandava C., Yarden O.,
RA Zeng Q., Rollins J.A., Lebrun M.H., Dickman M.;
RT "Genomic analysis of the necrotrophic fungal pathogens Sclerotinia
RT sclerotiorum and Botrytis cinerea.";
RL PLoS Genet. 7:E1002230-E1002230(2011).
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC -!- SIMILARITY: Belongs to the ORC4 family.
CC {ECO:0000256|ARBA:ARBA00005334}.
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DR EMBL; CH476634; EDN94059.1; -; Genomic_DNA.
DR RefSeq; XP_001589293.1; XM_001589243.1.
DR AlphaFoldDB; A7EX67; -.
DR STRING; 665079.A7EX67; -.
DR GeneID; 5485116; -.
DR KEGG; ssl:SS1G_09927; -.
DR VEuPathDB; FungiDB:sscle_01g002650; -.
DR InParanoid; A7EX67; -.
DR OMA; KMWRVDV; -.
DR OrthoDB; 230201at2759; -.
DR Proteomes; UP000001312; Unassembled WGS sequence.
DR GO; GO:0005664; C:nuclear origin of replication recognition complex; IBA:GO_Central.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0003688; F:DNA replication origin binding; IBA:GO_Central.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0006270; P:DNA replication initiation; IBA:GO_Central.
DR CDD; cd00009; AAA; 1.
DR CDD; cd15492; PHD_BRPF_JADE_like; 2.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 2.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR041664; AAA_16.
DR InterPro; IPR016527; ORC4.
DR InterPro; IPR032705; ORC4_C.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR011011; Znf_FYVE_PHD.
DR InterPro; IPR001965; Znf_PHD.
DR InterPro; IPR019787; Znf_PHD-finger.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR PANTHER; PTHR12087; ORIGIN RECOGNITION COMPLEX SUBUNIT 4; 1.
DR PANTHER; PTHR12087:SF0; ORIGIN RECOGNITION COMPLEX SUBUNIT 4; 1.
DR Pfam; PF13191; AAA_16; 1.
DR Pfam; PF14629; ORC4_C; 1.
DR Pfam; PF00628; PHD; 1.
DR Pfam; PF13831; PHD_2; 1.
DR SMART; SM00382; AAA; 1.
DR SMART; SM00249; PHD; 2.
DR SUPFAM; SSF57903; FYVE/PHD zinc finger; 2.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS50016; ZF_PHD_2; 2.
PE 3: Inferred from homology;
KW DNA replication {ECO:0000256|ARBA:ARBA00022705};
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000001312};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00146}.
FT DOMAIN 288..338
FT /note="PHD-type"
FT /evidence="ECO:0000259|PROSITE:PS50016"
FT DOMAIN 359..409
FT /note="PHD-type"
FT /evidence="ECO:0000259|PROSITE:PS50016"
FT REGION 1..39
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 87..236
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 251..284
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 9..23
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 165..203
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 251..271
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 883 AA; 97514 MW; 32B6A40F2C9C1A42 CRC64;
MAPSEPPSTR KRIRSRISDE VDELSPLPAR TQTSAAKRRK VDAPTYTLGG ISNRFKKLLG
LGAKKDTEDS ADELGEDIYD FKVTDDEEES TNVLGKPSAK PMAKNIKAAK STAKGVILSA
KRGRGRPRKN EDGLGKAKAL AQQAIQNETA KNKQDMEIET NDQDVESAEA PSKLSSGRST
RLSDSKNNIS GARGKTNGVP ESSTPKRGRP KRLIDGLGDS MGVVPKGILT PSKSRNSTIR
KSVAFDETGK DSLEGFKDIP SEPRSKKSRD KTIPSTSLTV TQNDEEEDPV CEICTKPDSK
RPNLILFCDG CPLAVHQKCY SVPKIPDGDW FCKKCQRNRV AAEAARANEN DALNDSDDEI
KCAVCRGLDS KKPNEIILCE NCDYAVHQTC GDIPKKPREE WLCKACVSHV DYDLLDGETD
LSPISIEVPT IEGFQTHLQT MQRVLLDRLT GQKRLRIHGH EDEVHKVHQL VEQTVLAGEG
NSMLIIGARG SGKTTLVESV ISDLEKVHRE SFHVVRLNGF IHTDDRLALR EIWRQLGREM
EIEDDSNGKI SNYADTLASL LALLSHPSEI SEIEADHTAK SVIFVLDEFD LFTTHSRQTL
LYNLFDIAQA RKAPIAVLGL TTRVDVVESL EKRVKSRFSH RYVHLSLPRS LPAFWGVCKE
GLIVDSDDYA EEGFDISTPG QREFLSFWQT MIEELYNNDA NFKHHILSHF YRSKSVPAFF
TSSILAISTL SMQNFPLRGQ SFNLANLALS APDSKLHILQ GLSELELAML IAAARLDIIL
DTDTCNFAMA YDEYSSLTSR HKVQTSSTGV TALGGSAKVW GRDVALGAWE RLVEYDLLIS
AAIGAAQVGG IAGRMWKVDI ALEEIPGSVE GLAGIMLKWC REI
//
