ID A7F8U4_SCLS1 Unreviewed; 1176 AA.
AC A7F8U4;
DT 11-SEP-2007, integrated into UniProtKB/TrEMBL.
DT 11-SEP-2007, sequence version 1.
DT 27-MAR-2024, entry version 84.
DE RecName: Full=RNA-directed DNA polymerase {ECO:0000256|ARBA:ARBA00012493};
DE EC=2.7.7.49 {ECO:0000256|ARBA:ARBA00012493};
GN ORFNames=SS1G_14025 {ECO:0000313|EMBL:EDN99165.1};
OS Sclerotinia sclerotiorum (strain ATCC 18683 / 1980 / Ss-1) (White mold)
OS (Whetzelinia sclerotiorum).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Leotiomycetes;
OC Helotiales; Sclerotiniaceae; Sclerotinia.
OX NCBI_TaxID=665079 {ECO:0000313|EMBL:EDN99165.1, ECO:0000313|Proteomes:UP000001312};
RN [1] {ECO:0000313|Proteomes:UP000001312}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 18683 / 1980 / Ss-1 {ECO:0000313|Proteomes:UP000001312};
RX PubMed=21876677; DOI=.1371/journal.pgen.1002230;
RA Amselem J., Cuomo C.A., van Kan J.A., Viaud M., Benito E.P., Couloux A.,
RA Coutinho P.M., de Vries R.P., Dyer P.S., Fillinger S., Fournier E.,
RA Gout L., Hahn M., Kohn L., Lapalu N., Plummer K.M., Pradier J.M.,
RA Quevillon E., Sharon A., Simon A., ten Have A., Tudzynski B., Tudzynski P.,
RA Wincker P., Andrew M., Anthouard V., Beever R.E., Beffa R., Benoit I.,
RA Bouzid O., Brault B., Chen Z., Choquer M., Collemare J., Cotton P.,
RA Danchin E.G., Da Silva C., Gautier A., Giraud C., Giraud T., Gonzalez C.,
RA Grossetete S., Guldener U., Henrissat B., Howlett B.J., Kodira C.,
RA Kretschmer M., Lappartient A., Leroch M., Levis C., Mauceli E.,
RA Neuveglise C., Oeser B., Pearson M., Poulain J., Poussereau N.,
RA Quesneville H., Rascle C., Schumacher J., Segurens B., Sexton A., Silva E.,
RA Sirven C., Soanes D.M., Talbot N.J., Templeton M., Yandava C., Yarden O.,
RA Zeng Q., Rollins J.A., Lebrun M.H., Dickman M.;
RT "Genomic analysis of the necrotrophic fungal pathogens Sclerotinia
RT sclerotiorum and Botrytis cinerea.";
RL PLoS Genet. 7:E1002230-E1002230(2011).
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DR EMBL; CH476648; EDN99165.1; -; Genomic_DNA.
DR RefSeq; XP_001585165.1; XM_001585115.1.
DR AlphaFoldDB; A7F8U4; -.
DR GeneID; 5481195; -.
DR KEGG; ssl:SS1G_14025; -.
DR InParanoid; A7F8U4; -.
DR OMA; RNSTWED; -.
DR OrthoDB; 1754396at2759; -.
DR Proteomes; UP000001312; Unassembled WGS sequence.
DR GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR CDD; cd00303; retropepsin_like; 1.
DR CDD; cd09274; RNase_HI_RT_Ty3; 1.
DR CDD; cd01647; RT_LTR; 1.
DR Gene3D; 1.10.340.70; -; 1.
DR Gene3D; 3.30.70.270; -; 1.
DR Gene3D; 2.40.70.10; Acid Proteases; 1.
DR Gene3D; 3.10.10.10; HIV Type 1 Reverse Transcriptase, subunit A, domain 1; 1.
DR Gene3D; 4.10.60.10; Zinc finger, CCHC-type; 1.
DR InterPro; IPR043502; DNA/RNA_pol_sf.
DR InterPro; IPR041588; Integrase_H2C2.
DR InterPro; IPR021109; Peptidase_aspartic_dom_sf.
DR InterPro; IPR005162; Retrotrans_gag_dom.
DR InterPro; IPR043128; Rev_trsase/Diguanyl_cyclase.
DR InterPro; IPR000477; RT_dom.
DR InterPro; IPR041373; RT_RNaseH.
DR InterPro; IPR001878; Znf_CCHC.
DR InterPro; IPR036875; Znf_CCHC_sf.
DR PANTHER; PTHR24559:SF437; RIBONUCLEASE H; 1.
DR PANTHER; PTHR24559; TRANSPOSON TY3-I GAG-POL POLYPROTEIN; 1.
DR Pfam; PF13650; Asp_protease_2; 1.
DR Pfam; PF17921; Integrase_H2C2; 1.
DR Pfam; PF03732; Retrotrans_gag; 1.
DR Pfam; PF17917; RT_RNaseH; 1.
DR Pfam; PF00078; RVT_1; 1.
DR Pfam; PF00098; zf-CCHC; 1.
DR SMART; SM00343; ZnF_C2HC; 1.
DR SUPFAM; SSF50630; Acid proteases; 1.
DR SUPFAM; SSF56672; DNA/RNA polymerases; 1.
DR SUPFAM; SSF57756; Retrovirus zinc finger-like domains; 1.
DR PROSITE; PS50158; ZF_CCHC; 1.
PE 4: Predicted;
KW Magnesium {ECO:0000256|ARBA:ARBA00022842};
KW Metal-binding {ECO:0000256|PROSITE-ProRule:PRU00047};
KW Reference proteome {ECO:0000313|Proteomes:UP000001312};
KW Zinc {ECO:0000256|PROSITE-ProRule:PRU00047};
KW Zinc-finger {ECO:0000256|PROSITE-ProRule:PRU00047}.
FT DOMAIN 255..270
FT /note="CCHC-type"
FT /evidence="ECO:0000259|PROSITE:PS50158"
FT REGION 1..35
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 197..233
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 591..620
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..22
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 197..224
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1176 AA; 135178 MW; CC92D063CE368515 CRC64;
MSSTTPQPSN PATTSQATPE STDKDGDIAM GGIEDPKEIT VTETLKDKFN HDADKSVWAA
SYLRGEAAKW IQPYLKDYFT NLGEPKKRMY PTQAIFGRFE GFKREIRRVF GNINELRDAE
SKIYGLKQTG SAVKYAVEFR RYIGTTGWEE NATMSHYRKG LKPEVRLELD RNSTWEDLNE
LIEESIKADE MLYEYQKERR SSNVHGNRDR GKYHKNEGRP RENRQSYGEP MQLDATFKNK
LPKEEVERRR KDKLCFECGK PGHRARDCRS KRSSGGGYHK KFGKGQLNAT FVPQLCASYP
IEDDSYEREE RQKEIDAMPR DQEGLNAIDR YELERLRTPS PPLIKEDPKE IPSVEHATMS
WIACYDESCR IHLSDKEATG WFPQRKAKRP YKKGRSEKLS SHDHLNGQLH KIDQIDQIDQ
IDQIDQIDQI DQIDQIDQID QIDHNKVLGQ GQLNIAGQAG QIYCNAKING RVIRAMIDSG
ATGNFIAPGT VKHLGVQLQA KRTPYQLQLV DGQLAGLDGK ISQETRPLQM SIAQHKGVIQ
FDVVPLGNQQ IILGMPWLKA HNPQIDWSSE TISFPRRSDQ RDVLEPARLN TRGGELKANS
TTDVGRPVQG PPLTAKEGEP PIQMKNKQKK LLETTPVEKQ DETPIPVQYQ KYKKLFEERK
GHEALPEHKP WDHEIVLEEG KTPPFGPIYP MSASDLRTLR DYIADALEKG WIRESTSQAA
SPVLFVPKKD GTRRLCVDYR KLNDITIKDR YPLPLATELR DRLGKAKIFS KFDLRNGFHL
IRMKEGEEWK TAFRTRYGLY EYQVMPFGLT NVPATFMEWE PPTSVKEVQS FLGFANFYRR
FIKNYSKIAA PMTEITKKSQ GEFRWTETAQ EAFERLKEAF AGEPVLRAFD PELPIIQPVA
YHSRKLSPAE LNYEIYDKEL LAIVDAFREW RVYLEGSKYT VQVYTDHKNL VYFTTTKELN
RRQVRWSETM AAYNFRISYV KGNENARADA LSRKPEYLQN KTHESRAILK QDGDALVHNK
PQLAATSGVN YDTIKDIIKT EYSTDATAKR ILAIPDNPER GFTIEDGFIH FHGKLYIPSS
LAKDYVTEQH ELPAHGHQGI ARTFARIRRE VYFPKMRTIV ENVVGNCDTC IRNKAARHAP
YGQLKTPELP TQPWKSIAWD FVVKLPLSKD PVTRKD
//
