ID A7GNG6_BACCN Unreviewed; 448 AA.
AC A7GNG6;
DT 11-SEP-2007, integrated into UniProtKB/TrEMBL.
DT 11-SEP-2007, sequence version 1.
DT 27-MAR-2024, entry version 84.
DE RecName: Full=Flagellar hook-associated protein 2 {ECO:0000256|RuleBase:RU362066};
DE Short=HAP2 {ECO:0000256|RuleBase:RU362066};
DE AltName: Full=Flagellar cap protein {ECO:0000256|RuleBase:RU362066};
GN OrderedLocusNames=Bcer98_1353 {ECO:0000313|EMBL:ABS21674.1};
OS Bacillus cytotoxicus (strain DSM 22905 / CIP 110041 / 391-98 / NVH 391-98).
OC Bacteria; Bacillota; Bacilli; Bacillales; Bacillaceae; Bacillus;
OC Bacillus cereus group.
OX NCBI_TaxID=315749 {ECO:0000313|EMBL:ABS21674.1, ECO:0000313|Proteomes:UP000002300};
RN [1] {ECO:0000313|EMBL:ABS21674.1, ECO:0000313|Proteomes:UP000002300}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 22905 / CIP 110041 / 391-98 / NVH 391-98
RC {ECO:0000313|Proteomes:UP000002300};
RX PubMed=17434157; DOI=10.1016/j.cbi.2007.03.003;
RA Lapidus A., Goltsman E., Auger S., Galleron N., Segurens B., Dossat C.,
RA Land M.L., Broussolle V., Brillard J., Guinebretiere M.-H., Sanchis V.,
RA Nguen-the C., Lereclus D., Richardson P., Wincker P., Weissenbach J.,
RA Ehrlich S.D., Sorokin A.;
RT "Extending the Bacillus cereus group genomics to putative food-borne
RT pathogens of different toxicity.";
RL Chem. Biol. Interact. 171:236-249(2008).
CC -!- FUNCTION: Required for morphogenesis and for the elongation of the
CC flagellar filament by facilitating polymerization of the flagellin
CC monomers at the tip of growing filament. Forms a capping structure,
CC which prevents flagellin subunits (transported through the central
CC channel of the flagellum) from leaking out without polymerization at
CC the distal end. {ECO:0000256|RuleBase:RU362066}.
CC -!- SUBUNIT: Homopentamer. {ECO:0000256|ARBA:ARBA00011255,
CC ECO:0000256|RuleBase:RU362066}.
CC -!- SUBCELLULAR LOCATION: Secreted {ECO:0000256|RuleBase:RU362066}.
CC Bacterial flagellum {ECO:0000256|RuleBase:RU362066}.
CC -!- SIMILARITY: Belongs to the FliD family. {ECO:0000256|ARBA:ARBA00009764,
CC ECO:0000256|RuleBase:RU362066}.
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DR EMBL; CP000764; ABS21674.1; -; Genomic_DNA.
DR RefSeq; WP_012093845.1; NC_009674.1.
DR AlphaFoldDB; A7GNG6; -.
DR STRING; 315749.Bcer98_1353; -.
DR GeneID; 56416938; -.
DR KEGG; bcy:Bcer98_1353; -.
DR eggNOG; COG1345; Bacteria.
DR HOGENOM; CLU_599428_0_0_9; -.
DR OrthoDB; 2364392at2; -.
DR Proteomes; UP000002300; Chromosome.
DR GO; GO:0009421; C:bacterial-type flagellum filament cap; IEA:InterPro.
DR GO; GO:0009424; C:bacterial-type flagellum hook; IEA:UniProtKB-UniRule.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR GO; GO:0007155; P:cell adhesion; IEA:InterPro.
DR InterPro; IPR040026; FliD.
DR InterPro; IPR010809; FliD_C.
DR InterPro; IPR003481; FliD_N.
DR PANTHER; PTHR30288; FLAGELLAR CAP/ASSEMBLY PROTEIN FLID; 1.
DR PANTHER; PTHR30288:SF0; FLAGELLAR HOOK-ASSOCIATED PROTEIN 2; 1.
DR Pfam; PF07195; FliD_C; 1.
DR Pfam; PF02465; FliD_N; 1.
PE 3: Inferred from homology;
KW Bacterial flagellum {ECO:0000256|ARBA:ARBA00023143,
KW ECO:0000256|RuleBase:RU362066};
KW Cell projection {ECO:0000313|EMBL:ABS21674.1};
KW Cilium {ECO:0000313|EMBL:ABS21674.1};
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054};
KW Flagellum {ECO:0000313|EMBL:ABS21674.1};
KW Secreted {ECO:0000256|RuleBase:RU362066}.
FT DOMAIN 22..115
FT /note="Flagellar hook-associated protein 2 N-terminal"
FT /evidence="ECO:0000259|Pfam:PF02465"
FT DOMAIN 224..428
FT /note="Flagellar hook-associated protein 2 C-terminal"
FT /evidence="ECO:0000259|Pfam:PF07195"
SQ SEQUENCE 448 AA; 48953 MW; 27E941B790443234 CRC64;
MGGTITNVGG RQQIWNLGNN IIDTSNLVNL ELQALEMKKT PYANQKQTLT NEKLIYASVK
KEFGNFYQIF KDLSAFKGNE KKTAASKDGF LTAQADASAI AGTYTITVEK VAQRHQITTA
PANSTNTTGT IQLDDKIGKD DTFKIGSKDV TVTKDMTYKD VVNKINNGNY GVSVYSLGGH
LFFTSTTEGK DGEIKLTDGS NGFLKSIGLI DSTGAIANEI TKPSDAEYTI NGIAGTSKSN
KISTLPGVTI NLEKETTEPI TLTIQDSDIK DSINLIKKMK DEYNKAVSSL DLFAGKNGAL
QGSSVAFSIQ NAMTNLFSYS QDKTFLFSFG IEVDKTGIMK LDEAKLATAF KENPETTKQF
FFGLNGLGHN MEKNLDKIFG DEGFIGKRSK SIDEQVSKLN QKISDIDTIN KTKQISIIDK
YAKLESTLAL LDMQLKTMKA MTKQKSDD
//
