ID A7HK96_FERNB Unreviewed; 294 AA.
AC A7HK96;
DT 11-SEP-2007, integrated into UniProtKB/TrEMBL.
DT 11-SEP-2007, sequence version 1.
DT 27-MAR-2024, entry version 75.
DE SubName: Full=Pyridoxal-5'-phosphate-dependent protein beta subunit {ECO:0000313|EMBL:ABS60329.1};
GN OrderedLocusNames=Fnod_0464 {ECO:0000313|EMBL:ABS60329.1};
OS Fervidobacterium nodosum (strain ATCC 35602 / DSM 5306 / Rt17-B1).
OC Bacteria; Thermotogota; Thermotogae; Thermotogales; Fervidobacteriaceae;
OC Fervidobacterium.
OX NCBI_TaxID=381764 {ECO:0000313|EMBL:ABS60329.1, ECO:0000313|Proteomes:UP000002415};
RN [1] {ECO:0000313|EMBL:ABS60329.1, ECO:0000313|Proteomes:UP000002415}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 35602 / DSM 5306 / Rt17-B1
RC {ECO:0000313|Proteomes:UP000002415};
RG US DOE Joint Genome Institute;
RA Copeland A., Lucas S., Lapidus A., Barry K., Glavina del Rio T., Dalin E.,
RA Tice H., Pitluck S., Saunders E., Brettin T., Bruce D., Detter J.C.,
RA Han C., Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N.,
RA Mikhailova N., Nelson K., Gogarten J.P., Noll K., Richardson P.;
RT "Complete sequence of Fervidobacterium nodosum Rt17-B1.";
RL Submitted (JUL-2007) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:ABS60329.1, ECO:0000313|Proteomes:UP000002415}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 35602 / DSM 5306 / Rt17-B1
RC {ECO:0000313|Proteomes:UP000002415};
RX PubMed=19307556; DOI=10.1073/pnas.0901260106;
RA Zhaxybayeva O., Swithers K.S., Lapierre P., Fournier G.P., Bickhart D.M.,
RA DeBoy R.T., Nelson K.E., Nesbo C.L., Doolittle W.F., Gogarten J.P.,
RA Noll K.M.;
RT "On the chimeric nature, thermophilic origin, and phylogenetic placement of
RT the Thermotogales.";
RL Proc. Natl. Acad. Sci. U.S.A. 106:5865-5870(2009).
CC -!- COFACTOR:
CC Name=pyridoxal 5'-phosphate; Xref=ChEBI:CHEBI:597326;
CC Evidence={ECO:0000256|ARBA:ARBA00001933};
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DR EMBL; CP000771; ABS60329.1; -; Genomic_DNA.
DR AlphaFoldDB; A7HK96; -.
DR STRING; 381764.Fnod_0464; -.
DR KEGG; fno:Fnod_0464; -.
DR eggNOG; COG0031; Bacteria.
DR HOGENOM; CLU_021018_1_0_0; -.
DR Proteomes; UP000002415; Chromosome.
DR GO; GO:0019344; P:cysteine biosynthetic process; IEA:UniProt.
DR CDD; cd01561; CBS_like; 1.
DR Gene3D; 3.40.50.1100; -; 2.
DR InterPro; IPR001926; TrpB-like_PALP.
DR InterPro; IPR036052; TrpB-like_PALP_sf.
DR PANTHER; PTHR10314; CYSTATHIONINE BETA-SYNTHASE; 1.
DR PANTHER; PTHR10314:SF194; CYSTATHIONINE BETA-SYNTHASE; 1.
DR Pfam; PF00291; PALP; 1.
DR SUPFAM; SSF53686; Tryptophan synthase beta subunit-like PLP-dependent enzymes; 1.
PE 4: Predicted;
KW Pyridoxal phosphate {ECO:0000256|ARBA:ARBA00022898};
KW Reference proteome {ECO:0000313|Proteomes:UP000002415}.
FT DOMAIN 12..284
FT /note="Tryptophan synthase beta chain-like PALP"
FT /evidence="ECO:0000259|Pfam:PF00291"
SQ SEQUENCE 294 AA; 32401 MW; C936500EC702BA1B CRC64;
MLSYLSKISS IRIGKTPLIY IDKYGIYAKF ERNNPIGSVK DRPVYFMIRD AIKSGKINEN
TVFVEPTSGN TGIALAWLGA RLGLKVILTM PESVSVERMN MLKALGADLI LVENMTKAVE
KALEIVSERS AFMPNQFENP ANSLAHEITT GPEILEEMNF LVDAFVAGVG TGGTITGVGR
VLKRLLKENV KVCALEPLQS PVLTNGISGK HRIQGIAPGF VPKILDRQLI DEIKLIVDEE
ALNMMKILWK EGLFVGVSSA ANLLGAIYIK EKYKFERVVT IFPDDGTKYL SLIQ
//
