ID A7HU20_PARL1 Unreviewed; 493 AA.
AC A7HU20;
DT 11-SEP-2007, integrated into UniProtKB/TrEMBL.
DT 11-SEP-2007, sequence version 1.
DT 27-MAR-2024, entry version 69.
DE SubName: Full=4-hydroxyphenylacetate 3-hydroxylase {ECO:0000313|EMBL:ABS63403.1};
GN OrderedLocusNames=Plav_1785 {ECO:0000313|EMBL:ABS63403.1};
OS Parvibaculum lavamentivorans (strain DS-1 / DSM 13023 / NCIMB 13966).
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Hyphomicrobiales;
OC Parvibaculaceae; Parvibaculum.
OX NCBI_TaxID=402881 {ECO:0000313|EMBL:ABS63403.1, ECO:0000313|Proteomes:UP000006377};
RN [1] {ECO:0000313|EMBL:ABS63403.1, ECO:0000313|Proteomes:UP000006377}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DS-1 / DSM 13023 / NCIMB 13966
RC {ECO:0000313|Proteomes:UP000006377};
RX PubMed=22675581; DOI=10.4056/sigs.2215005;
RA Schleheck D., Weiss M., Pitluck S., Bruce D., Land M.L., Han S.,
RA Saunders E., Tapia R., Detter C., Brettin T., Han J., Woyke T., Goodwin L.,
RA Pennacchio L., Nolan M., Cook A.M., Kjelleberg S., Thomas T.;
RT "Complete genome sequence of Parvibaculum lavamentivorans type strain (DS-
RT 1(T)).";
RL Stand. Genomic Sci. 5:298-310(2011).
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DR EMBL; CP000774; ABS63403.1; -; Genomic_DNA.
DR RefSeq; WP_012110696.1; NC_009719.1.
DR AlphaFoldDB; A7HU20; -.
DR STRING; 402881.Plav_1785; -.
DR KEGG; pla:Plav_1785; -.
DR eggNOG; COG2368; Bacteria.
DR HOGENOM; CLU_023920_2_1_5; -.
DR OrthoDB; 7233724at2; -.
DR Proteomes; UP000006377; Chromosome.
DR GO; GO:0016627; F:oxidoreductase activity, acting on the CH-CH group of donors; IEA:InterPro.
DR Gene3D; 1.10.3140.10; 4-hydroxybutyryl-coa dehydratase, domain 1; 1.
DR Gene3D; 2.40.110.10; Butyryl-CoA Dehydrogenase, subunit A, domain 2; 1.
DR Gene3D; 1.20.140.10; Butyryl-CoA Dehydrogenase, subunit A, domain 3; 1.
DR InterPro; IPR046373; Acyl-CoA_Oxase/DH_mid-dom_sf.
DR InterPro; IPR036250; AcylCo_DH-like_C.
DR InterPro; IPR009100; AcylCoA_DH/oxidase_NM_dom_sf.
DR InterPro; IPR004925; HpaB/PvcC/4-BUDH.
DR InterPro; IPR024719; HpaB/PvcC/4-BUDH_C.
DR InterPro; IPR024674; HpaB/PvcC/4-BUDH_N.
DR PANTHER; PTHR36117; 4-HYDROXYPHENYLACETATE 3-MONOOXYGENASE-RELATED; 1.
DR PANTHER; PTHR36117:SF3; 4-HYDROXYPHENYLACETATE 3-MONOOXYGENASE-RELATED; 1.
DR Pfam; PF03241; HpaB; 1.
DR Pfam; PF11794; HpaB_N; 1.
DR PIRSF; PIRSF000331; HpaA_HpaB; 1.
DR SUPFAM; SSF47203; Acyl-CoA dehydrogenase C-terminal domain-like; 1.
DR SUPFAM; SSF56645; Acyl-CoA dehydrogenase NM domain-like; 1.
PE 4: Predicted;
KW FAD {ECO:0000256|PIRSR:PIRSR000331-2};
KW Flavoprotein {ECO:0000256|ARBA:ARBA00022630};
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW Reference proteome {ECO:0000313|Proteomes:UP000006377}.
FT DOMAIN 5..268
FT /note="HpaB/PvcC/4-BUDH N-terminal"
FT /evidence="ECO:0000259|Pfam:PF11794"
FT DOMAIN 290..475
FT /note="HpaB/PvcC/4-BUDH C-terminal"
FT /evidence="ECO:0000259|Pfam:PF03241"
FT BINDING 147..149
FT /ligand="FAD"
FT /ligand_id="ChEBI:CHEBI:57692"
FT /evidence="ECO:0000256|PIRSR:PIRSR000331-2"
FT BINDING 190
FT /ligand="FAD"
FT /ligand_id="ChEBI:CHEBI:57692"
FT /evidence="ECO:0000256|PIRSR:PIRSR000331-2"
SQ SEQUENCE 493 AA; 54954 MW; BAE4210D0527C63F CRC64;
MPARTGAQFL EGLKQPREIW VGDRKIESVA DDPAFAGAAR GVAAVYDLQH KEADACLMPD
PETGEKINVS HMIPRSRQDL ARRRAGLEKI AAYSVGLMGR TPDYMNVTYA GFAGRAEEWA
VNGNEEGAEN LVNYQKYLRR NDISLTHTIV NPTIDKAQGD APQPGNDVAL RKVGETEHGI
VVRGARILAT LAPFADEIAV YPSHPLPPDC DEYAISFCIP MSTPGLKFIC RDSFSESSNF
FDHPISGRFD EQDAFVIFDN VEVPRNRLHV NCNTAVYNSV MMRSWWPNVM QQTTVRALTK
LEFAWGLASR MTEVINDVKP QTWEMLGEIW SYAELTRACL KAAEDGAIDY GNGVWLPDAQ
PFAALRASMP RWMARVSEII QLIGSHNVFA APSRAQLDDA GLRPLIDHYL RGAGDVGAEQ
RARVFRLAWD FVGTGLAGRN LQYERFYLGS SVRNYQMAHL FGDRTRANEL VDRFLTEDIG
AMKKADRHVA EAV
//
