ID A7I4N2_METB6 Unreviewed; 295 AA.
AC A7I4N2;
DT 11-SEP-2007, integrated into UniProtKB/TrEMBL.
DT 11-SEP-2007, sequence version 1.
DT 27-MAR-2024, entry version 63.
DE SubName: Full=Thiamine pyrophosphate enzyme domain protein TPP-binding {ECO:0000313|EMBL:ABS54693.1};
GN OrderedLocusNames=Mboo_0170 {ECO:0000313|EMBL:ABS54693.1};
OS Methanoregula boonei (strain DSM 21154 / JCM 14090 / 6A8).
OC Archaea; Euryarchaeota; Stenosarchaea group; Methanomicrobia;
OC Methanomicrobiales; Methanoregulaceae; Methanoregula.
OX NCBI_TaxID=456442 {ECO:0000313|EMBL:ABS54693.1, ECO:0000313|Proteomes:UP000002408};
RN [1] {ECO:0000313|Proteomes:UP000002408}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 21154 / JCM 14090 / 6A8
RC {ECO:0000313|Proteomes:UP000002408};
RX PubMed=25998264; DOI=10.1099/mic.0.000117;
RA Braeuer S., Cadillo-Quiroz H., Kyrpides N., Woyke T., Goodwin L.,
RA Detter C., Podell S., Yavitt J.B., Zinder S.H.;
RT "Genome of Methanoregula boonei 6A8 reveals adaptations to oligotrophic
RT peatland environments.";
RL Microbiology 161:1572-1581(2015).
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DR EMBL; CP000780; ABS54693.1; -; Genomic_DNA.
DR AlphaFoldDB; A7I4N2; -.
DR STRING; 456442.Mboo_0170; -.
DR KEGG; mbn:Mboo_0170; -.
DR eggNOG; arCOG01601; Archaea.
DR HOGENOM; CLU_058423_0_0_2; -.
DR Proteomes; UP000002408; Chromosome.
DR GO; GO:0003824; F:catalytic activity; IEA:InterPro.
DR GO; GO:0030976; F:thiamine pyrophosphate binding; IEA:InterPro.
DR GO; GO:0006082; P:organic acid metabolic process; IEA:UniProt.
DR GO; GO:1901576; P:organic substance biosynthetic process; IEA:UniProt.
DR GO; GO:0044272; P:sulfur compound biosynthetic process; IEA:UniProt.
DR CDD; cd03376; TPP_PFOR_porB_like; 1.
DR Gene3D; 3.40.50.970; -; 2.
DR InterPro; IPR029061; THDP-binding.
DR InterPro; IPR011766; TPP_enzyme_TPP-bd.
DR PANTHER; PTHR42897:SF1; 2-OXOACID OXIDOREDUCTASE (FERREDOXIN); 1.
DR PANTHER; PTHR42897; PYRUVATE SYNTHASE SUBUNIT PORB; 1.
DR Pfam; PF02775; TPP_enzyme_C; 1.
DR SUPFAM; SSF52518; Thiamin diphosphate-binding fold (THDP-binding); 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000002408}.
FT DOMAIN 48..202
FT /note="Thiamine pyrophosphate enzyme TPP-binding"
FT /evidence="ECO:0000259|Pfam:PF02775"
SQ SEQUENCE 295 AA; 31180 MW; 19C9A9ADB174D5D8 CRC64;
MVVIAEIPST EYVLNCTSAC AGCGDSLALR YVLKAAGPDT ILVMPAGCTA AFQGVYPKTA
YALPVVNIAF AAAAASASGL STFLRAKGKK TKVVVYAGDG ATLDIGLSAV SGAFERRTDF
LYVCYDNEAY GNTGMQRSGA TPIGAKTTTT PAGKPEIKKD IDTIIAAHEP PYQATACAAY
PQDLFRKVQK ALTFEGPTFV HILTPCPPGW RYSAEKTVEL GKLAVKSGIW ALYERENGKL
VISAPTKAAM KKPVPLEEYL APQGRFKGID SATVALLKGR IAENFRRLAA EEAGS
//
