ID A7I9P8_METB6 Unreviewed; 222 AA.
AC A7I9P8;
DT 11-SEP-2007, integrated into UniProtKB/TrEMBL.
DT 11-SEP-2007, sequence version 1.
DT 24-JAN-2024, entry version 68.
DE SubName: Full=TrkA-N domain protein {ECO:0000313|EMBL:ABS56459.1};
GN OrderedLocusNames=Mboo_1944 {ECO:0000313|EMBL:ABS56459.1};
OS Methanoregula boonei (strain DSM 21154 / JCM 14090 / 6A8).
OC Archaea; Euryarchaeota; Stenosarchaea group; Methanomicrobia;
OC Methanomicrobiales; Methanoregulaceae; Methanoregula.
OX NCBI_TaxID=456442 {ECO:0000313|EMBL:ABS56459.1, ECO:0000313|Proteomes:UP000002408};
RN [1] {ECO:0000313|Proteomes:UP000002408}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 21154 / JCM 14090 / 6A8
RC {ECO:0000313|Proteomes:UP000002408};
RX PubMed=25998264; DOI=10.1099/mic.0.000117;
RA Braeuer S., Cadillo-Quiroz H., Kyrpides N., Woyke T., Goodwin L.,
RA Detter C., Podell S., Yavitt J.B., Zinder S.H.;
RT "Genome of Methanoregula boonei 6A8 reveals adaptations to oligotrophic
RT peatland environments.";
RL Microbiology 161:1572-1581(2015).
CC -!- FUNCTION: Part of a potassium transport system.
CC {ECO:0000256|ARBA:ARBA00003660}.
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DR EMBL; CP000780; ABS56459.1; -; Genomic_DNA.
DR RefSeq; WP_012107514.1; NC_009712.1.
DR AlphaFoldDB; A7I9P8; -.
DR STRING; 456442.Mboo_1944; -.
DR GeneID; 5412099; -.
DR KEGG; mbn:Mboo_1944; -.
DR eggNOG; arCOG01957; Archaea.
DR HOGENOM; CLU_046525_2_3_2; -.
DR OMA; RWTADQM; -.
DR OrthoDB; 24929at2157; -.
DR Proteomes; UP000002408; Chromosome.
DR GO; GO:0005886; C:plasma membrane; IEA:InterPro.
DR GO; GO:0015079; F:potassium ion transmembrane transporter activity; IEA:InterPro.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR Gene3D; 3.30.70.1450; Regulator of K+ conductance, C-terminal domain; 1.
DR InterPro; IPR006036; K_uptake_TrkA.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR InterPro; IPR006037; RCK_C.
DR InterPro; IPR036721; RCK_C_sf.
DR InterPro; IPR003148; RCK_N.
DR PANTHER; PTHR43833; POTASSIUM CHANNEL PROTEIN 2-RELATED-RELATED; 1.
DR PANTHER; PTHR43833:SF5; TRK SYSTEM POTASSIUM UPTAKE PROTEIN TRKA; 1.
DR Pfam; PF02080; TrkA_C; 1.
DR Pfam; PF02254; TrkA_N; 1.
DR PRINTS; PR00335; KUPTAKETRKA.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
DR SUPFAM; SSF116726; TrkA C-terminal domain-like; 1.
DR PROSITE; PS51202; RCK_C; 1.
DR PROSITE; PS51201; RCK_N; 1.
PE 4: Predicted;
KW NAD {ECO:0000256|ARBA:ARBA00023027};
KW Reference proteome {ECO:0000313|Proteomes:UP000002408}.
FT DOMAIN 2..124
FT /note="RCK N-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51201"
FT DOMAIN 133..215
FT /note="RCK C-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51202"
SQ SEQUENCE 222 AA; 24533 MW; EE172F8D9A061F63 CRC64;
MYIIIVGLGG IGRSLVRQAV EHGNNVVVID QDEARCSEIL EHYDILAITG NATDKSTLEE
AGIDRTDAFV ATTSDDAVNL MTCWLAKRFH VPNVVAIVNQ PAHSEFFKEV GVRISENPDD
LVASRLYYWT ENPKLQQLAS IPGGSIFEIM AEENAPIVGH EIRELKVKDF VFIAIRRAGG
ALIIPSGNVR IQPGDVFTVF TKKEAEEDCL RLLNKQLKKS AD
//