ID A7IE17_XANP2 Unreviewed; 2706 AA.
AC A7IE17;
DT 11-SEP-2007, integrated into UniProtKB/TrEMBL.
DT 11-SEP-2007, sequence version 1.
DT 27-MAR-2024, entry version 99.
DE SubName: Full=Amino acid adenylation domain {ECO:0000313|EMBL:ABS66260.1};
GN OrderedLocusNames=Xaut_1009 {ECO:0000313|EMBL:ABS66260.1};
OS Xanthobacter autotrophicus (strain ATCC BAA-1158 / Py2).
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Hyphomicrobiales;
OC Xanthobacteraceae; Xanthobacter.
OX NCBI_TaxID=78245 {ECO:0000313|EMBL:ABS66260.1, ECO:0000313|Proteomes:UP000002417};
RN [1] {ECO:0000313|EMBL:ABS66260.1, ECO:0000313|Proteomes:UP000002417}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC BAA-1158 / Py2 {ECO:0000313|Proteomes:UP000002417};
RG US DOE Joint Genome Institute;
RA Copeland A., Lucas S., Lapidus A., Barry K., Glavina del Rio T., Hammon N.,
RA Israni S., Dalin E., Tice H., Pitluck S., Sims D., Brettin T., Bruce D.,
RA Detter J.C., Han C., Tapia R., Brainard J., Schmutz J., Larimer F.,
RA Land M., Hauser L., Kyrpides N., Kim E., Ensigns S.A., Richardson P.;
RT "Complete sequence of chromosome of Xanthobacter autotrophicus Py2.";
RL Submitted (JUL-2007) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; CP000781; ABS66260.1; -; Genomic_DNA.
DR STRING; 78245.Xaut_1009; -.
DR KEGG; xau:Xaut_1009; -.
DR eggNOG; COG1020; Bacteria.
DR HOGENOM; CLU_000022_0_8_5; -.
DR OrthoDB; 9803968at2; -.
DR PhylomeDB; A7IE17; -.
DR Proteomes; UP000002417; Chromosome.
DR GO; GO:0016491; F:oxidoreductase activity; IEA:InterPro.
DR GO; GO:0031177; F:phosphopantetheine binding; IEA:InterPro.
DR GO; GO:0043604; P:amide biosynthetic process; IEA:UniProt.
DR CDD; cd05930; A_NRPS; 1.
DR CDD; cd19535; Cyc_NRPS; 1.
DR CDD; cd19531; LCL_NRPS-like; 1.
DR CDD; cd02142; McbC_SagB-like_oxidoreductase; 1.
DR Gene3D; 3.30.300.30; -; 2.
DR Gene3D; 3.40.50.980; -; 4.
DR Gene3D; 1.10.1200.10; ACP-like; 2.
DR Gene3D; 3.30.559.10; Chloramphenicol acetyltransferase-like domain; 2.
DR Gene3D; 3.40.109.10; NADH Oxidase; 1.
DR Gene3D; 3.30.559.30; Nonribosomal peptide synthetase, condensation domain; 2.
DR Gene3D; 3.40.50.150; Vaccinia Virus protein VP39; 1.
DR InterPro; IPR010071; AA_adenyl_domain.
DR InterPro; IPR036736; ACP-like_sf.
DR InterPro; IPR045851; AMP-bd_C_sf.
DR InterPro; IPR020845; AMP-binding_CS.
DR InterPro; IPR000873; AMP-dep_Synth/Lig_com.
DR InterPro; IPR023213; CAT-like_dom_sf.
DR InterPro; IPR001242; Condensatn.
DR InterPro; IPR006342; FkbM_mtfrase.
DR InterPro; IPR029479; Nitroreductase.
DR InterPro; IPR000415; Nitroreductase-like.
DR InterPro; IPR020806; PKS_PP-bd.
DR InterPro; IPR009081; PP-bd_ACP.
DR InterPro; IPR029063; SAM-dependent_MTases_sf.
DR NCBIfam; TIGR01733; AA-adenyl-dom; 2.
DR NCBIfam; TIGR01444; fkbM_fam; 1.
DR PANTHER; PTHR45527; NONRIBOSOMAL PEPTIDE SYNTHETASE; 1.
DR PANTHER; PTHR45527:SF10; PHENYLOXAZOLINE SYNTHASE MBTB; 1.
DR Pfam; PF00501; AMP-binding; 2.
DR Pfam; PF00668; Condensation; 2.
DR Pfam; PF05050; Methyltransf_21; 1.
DR Pfam; PF00881; Nitroreductase; 1.
DR Pfam; PF00550; PP-binding; 2.
DR SMART; SM00823; PKS_PP; 2.
DR SUPFAM; SSF56801; Acetyl-CoA synthetase-like; 2.
DR SUPFAM; SSF47336; ACP-like; 2.
DR SUPFAM; SSF52777; CoA-dependent acyltransferases; 4.
DR SUPFAM; SSF55469; FMN-dependent nitroreductase-like; 1.
DR SUPFAM; SSF53335; S-adenosyl-L-methionine-dependent methyltransferases; 1.
DR PROSITE; PS00455; AMP_BINDING; 2.
DR PROSITE; PS50075; CARRIER; 2.
PE 4: Predicted;
KW Phosphopantetheine {ECO:0000256|ARBA:ARBA00022450};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Reference proteome {ECO:0000313|Proteomes:UP000002417}.
FT DOMAIN 1273..1348
FT /note="Carrier"
FT /evidence="ECO:0000259|PROSITE:PS50075"
FT DOMAIN 2592..2667
FT /note="Carrier"
FT /evidence="ECO:0000259|PROSITE:PS50075"
FT REGION 22..42
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2687..2706
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 2706 AA; 291622 MW; 89514DC5EFEE81B6 CRC64;
MNIEERLAQL SPQQRELLAR RLGQRPQAPA APRIPPQPRD GRGFPLSFAQ ERLWFEHQID
PLSVAYNEAV VLRVRGPLRL DFIGAALDEL IARHEILRTG IVSAGGTAEQ VIAPPAPLPL
ERRDLAGQGD EALDEAIREV IRRPFALAMP PLLRLCALEL GPDEQVLVFA VHHIVLDGWS
AAGLFREIFA VYGARQRGER LPAPAPQVQY ADYAVWERAR FASGALDGER DFWTRTLADA
PPPPALPLDR PRPALRGTSG GRVVFRCDAD LSAALRTLAQ SCETTLFATL AAAYGVLLSR
HGGIDDVLLA VPSTTRDLPE LESAVGLFIN TLVLRLRLDA QASFRDALGA VSAAATGARA
HQLYPHERLV EHLRRERDLG PVPLTALMFD VQKLPAGIAP AGLTVEYLDV DPGTSKFDLG
LSIKDDGAGL VGTFEYSADL FDRTSVEAMA RQFQALLADI AARPDAELAD LALMSDEEAR
EALAAGLGPA LEIGPERRLH VLFAAVAARQ PEAIAVTCGA DSLTYAELDA AANRLSHRLI
SLGAGPGQAV ALRLQRSVGL IIGLVGILKA GAAYVPLDPH WPAARQAEIL AQSGARIAVA
HAADGALGEG ITLCDPAIAD EPATAPEIAV GPDDPAYILY TSGSTGRPRG VLVPHGAVVN
LFHALHASVH AGLGDGPLRV AMNGPVVFDT SVKQIIQLLG GHTLDVIPDA AREDPAALVA
YLRDHAIDVL DVTPTHLSML LAEGLLAPGH ARPKAVLVGG EPIDGALWAQ LAAPSDVRFF
NLYGPTECTV DATAALIAGP VPHMGWALAN VRTYVLNGAG RPVPQGVAGE LYIGGAGVAR
GYLGEPELTA RRFVALPFDN GPVYRTGDLV RRRADGSLVF LGRADAQVKL RGYRIEPGEI
AAALKAVEGV RDAAVVLHGA GAMQRLVAYV VADPARAPLV SGAPRHVLPN GLAVAHLNRN
ETDFLYEEMF ELEAYFRHGV ELRAGDTVFD VGANIGLFTL AAHLAVPDVR VHAFEPNPTV
CALARANAAL YGVAATVHNT GLAAAPGQAA FTFYPGFSFL SGLHADRAAD ADVVRSFVRK
HDSEGGEGFA PALLEELLED RLASRTLDVA LDTLSDVMAR EGVERIDLLK INVEKSEAEV
LAGIRANDWP KIRQVALELH DINGRLESVL ALLKAQGFIV SAEQDWRLEE SAKTNFYLYA
HRGLRPGSRP PRAAILPVLD AEGLRVALAG RLPDYMVPAD IIFLDALPLT PNGKLDTRAL
PAPTAPAAPE AAAPRTETER RLATLWAEVL QREAVGIHDD FFRIGGHSLL ATLLMAQLRA
RFDVALPLRA LFEAPTVARL AARIEAEPVV ADGADAAAGL PQLTPDPAAW HESFPLTPIQ
EAYWMGRTAT FELGQAATQI YLELEQVGWD LPRIEAAWNR LVKRHDMLRA IILSEERQQV
LAEVPYYSIA VEDLRGRPAD AVERHLAEVR AAMSGQTLPA DRWPLFQIRA TLMDGGRVRL
HVGVDALIAD AASLFLLFDE WRRSYEADGD TRPPLAIGFR DYVLAERGLH QGALYQAAQR
YWFDRLDTLP PAPDLPVDRA AAAALDKPHF VRRSRRLSPA QWQALKDRAA KAGLTPSLVL
IAAYAQALAN WSASPRFTLN LTTFNRLPLH PDVTGLMGDF TTLTLLEADH SQPASFLDRA
RALQARLWDD LEHRTISGIE VLRALAQRRR SGVSALMPVV FTSALDIDPA GQKAQRFGEV
VESVSQTPQV WLDHQVMEWN GTLVLNWDAV EAIFPPGLLD DFATAHGDLV ERLATSDSAW
SEAQGRLAPA AQIARRAAVN RTREDFPPRR LEDAFRAHAA AHPEAVALLT SRRAVTYGEL
NRRAAEIAGL LRARGEGPGR LVAVVMRKDW EQVAAVLGIL MAGAAYLPVD PDLPSERRAY
LLAHCDVTTA LTQSAVDAAL DWPDGIARIA VDLLEATGGA SADIGPFSLD DLAYVLFTSG
STGVPKGVMI SQRAIANSIA DFTRRYGFTP RDRTLGLSAL GFDLSVFDIF CPLSAGGAIV
LPDADKLRDP EHWADLARRH NVTVWQSVPV LMQMMVEALE PRRELWPASL RCVVMSGDWI
PVSLPDRIRA FDPAIALHGQ GGATETSINA VVYPIGAVDP AWRSIPYGKP FANQTAHILN
ALLEPAPDHV PGELYIGGTG LADGYWKDEA KTRAAFIRHP RTGERLYRTG DYGRFLPDGN
IEFLGRRDTQ IKVNGHRIEL GEIEAVLAQH PGVEHAVAAA PADALGHRRL VAYVVLKPRP
EAEQEPGGDL STDNVLADPM ARVAFKLDRH GLRAPAPDAE TVALPGGSFD AARRAAWLAR
QSFRHFEGEG VTMERLGALL GALQELPMEG APLPKFRYPS AGSLYPVQAY VVAKPGRVAG
LAGGAYYYDP SRHRLVAVGP GAEMTPLYPG PNRPLVEASA FSLVLVGRRA AVEPLYGPLW
RDFCLLEAGY MGQLLSAAAP EHRLGLCPLG FLAEGPARAL LGLDDADVVL HSFAGGAITE
AQLASWSPEE VPQQPSPVDE LRAYLRRKLP DYMLPSSFIL LDALPLSANG KVDRDALPSP
DAVLPAADAG AAPATDVEKT IAEVVEAVLQ LPALGLDSNF FDLGANSVHL VQIHRRLQEQ
LARTFPLVDL FQNPSIRRLA LFLDGGAAAL ETDDIVARVE RAKQDRARRL ARRRTGGNST
EAEAAS
//
