ID A7IIM7_XANP2 Unreviewed; 598 AA.
AC A7IIM7;
DT 11-SEP-2007, integrated into UniProtKB/TrEMBL.
DT 11-SEP-2007, sequence version 1.
DT 27-MAR-2024, entry version 61.
DE SubName: Full=Xanthine/uracil/vitamin C permease {ECO:0000313|EMBL:ABS67870.1};
GN OrderedLocusNames=Xaut_2628 {ECO:0000313|EMBL:ABS67870.1};
OS Xanthobacter autotrophicus (strain ATCC BAA-1158 / Py2).
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Hyphomicrobiales;
OC Xanthobacteraceae; Xanthobacter.
OX NCBI_TaxID=78245 {ECO:0000313|EMBL:ABS67870.1, ECO:0000313|Proteomes:UP000002417};
RN [1] {ECO:0000313|EMBL:ABS67870.1, ECO:0000313|Proteomes:UP000002417}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC BAA-1158 / Py2 {ECO:0000313|Proteomes:UP000002417};
RG US DOE Joint Genome Institute;
RA Copeland A., Lucas S., Lapidus A., Barry K., Glavina del Rio T., Hammon N.,
RA Israni S., Dalin E., Tice H., Pitluck S., Sims D., Brettin T., Bruce D.,
RA Detter J.C., Han C., Tapia R., Brainard J., Schmutz J., Larimer F.,
RA Land M., Hauser L., Kyrpides N., Kim E., Ensigns S.A., Richardson P.;
RT "Complete sequence of chromosome of Xanthobacter autotrophicus Py2.";
RL Submitted (JUL-2007) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC
CC 2.A.40) family. {ECO:0000256|ARBA:ARBA00008821}.
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DR EMBL; CP000781; ABS67870.1; -; Genomic_DNA.
DR AlphaFoldDB; A7IIM7; -.
DR STRING; 78245.Xaut_2628; -.
DR KEGG; xau:Xaut_2628; -.
DR eggNOG; COG2233; Bacteria.
DR HOGENOM; CLU_017959_8_3_5; -.
DR Proteomes; UP000002417; Chromosome.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0015205; F:nucleobase transmembrane transporter activity; IEA:UniProt.
DR InterPro; IPR006043; NCS2.
DR NCBIfam; NF037981; NCS2_1; 1.
DR PANTHER; PTHR42810; PURINE PERMEASE C1399.01C-RELATED; 1.
DR PANTHER; PTHR42810:SF4; URIC ACID TRANSPORTER UACT; 1.
DR Pfam; PF00860; Xan_ur_permease; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000002417};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 50..72
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 84..104
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 137..155
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 167..184
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 196..217
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 224..243
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 273..296
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 353..372
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 378..399
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 411..430
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 442..460
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
SQ SEQUENCE 598 AA; 63231 MW; F081F4ED644C53A5 CRC64;
MLDAKARSRS PRSHIRRVIE RLFPDPRRGS RTLRRPASLV YGLDDKVPPV ALVPLAAQHA
MLAVTFLIYP VLAATEARLP ADQMSAMLSA CAMSIGVATI IQCLRTRFGS GYLAVHIPAP
GAIPLAAQAL MLGGLGLMAM TTLLVGICQL FMARLVRPLR VLLPPEVCGV AVSMLGVSLA
GPALRRALGL DHGPLVVQNA TFSSLATVGI IVAITVFAPR RLKLFAVFAG AGIGWVLALL
LGAGHPEANA AIAAAPLVAW PTLTLPSLQF APALFPLMAL LVMMNLVDVL SVTVSLEKMN
DADWRRADMQ AAQRAVTACG IGNILNGLTS GFQSGLSSSS VGLAFATQST ARIIGILAGA
MIFAIAFLPK AIVALTLIPS PVIGGILLYT SAYLVVAGMD LVTSRRLSER RVFVVGLSVL
AGLSVALLPL RDQLPLALQP LFSTPLTVGA LSAILLNLLF RIGIARETGE IVPDGAHAFP
FARDFLERQG DVWGARRDVI AAAIPTVAQA LELVIDAGIA EGPIELRARF DETHLDVYLI
YDGEVVEAPK ERPSPEALLG DAKEHASFAA WMLKRLSDHV HFGRTGGGKA RIALSFDH
//
