ID   A7K9B0_9PHYC            Unreviewed;       162 AA.
AC   A7K9B0;
DT   11-SEP-2007, integrated into UniProtKB/TrEMBL.
DT   11-SEP-2007, sequence version 1.
DT   13-SEP-2023, entry version 59.
DE   RecName: Full=dUTP diphosphatase {ECO:0000256|ARBA:ARBA00012379};
DE            EC=3.6.1.23 {ECO:0000256|ARBA:ARBA00012379};
GN   Name=Z500L {ECO:0000313|EMBL:ABT16634.1};
GN   ORFNames=ATCV1_Z500L {ECO:0000313|EMBL:ABT16634.1};
OS   Acanthocystis turfacea chlorella virus 1.
OC   Viruses; Varidnaviria; Bamfordvirae; Nucleocytoviricota; Megaviricetes;
OC   Algavirales; Phycodnaviridae; Chlorovirus.
OX   NCBI_TaxID=322019 {ECO:0000313|EMBL:ABT16634.1, ECO:0000313|Proteomes:UP000202420};
RN   [1] {ECO:0000313|EMBL:ABT16634.1, ECO:0000313|Proteomes:UP000202420}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCV-1 {ECO:0000313|EMBL:ABT16634.1,
RC   ECO:0000313|Proteomes:UP000202420};
RA   Fitzgerald L.A., Graves M.V., Li X., Pfitzner A.J.P., Hartigan J.,
RA   Van Etten J.L.;
RT   "Sequence and annotation of the 288-kb ATCV-1 virus that infects an
RT   endosymbiotic Chlorella strain of the heliozoon Acanthocystis turfacea.";
RL   Submitted (SEP-2006) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: This enzyme is involved in nucleotide metabolism: it produces
CC       dUMP, the immediate precursor of thymidine nucleotides and it decreases
CC       the intracellular concentration of dUTP so that uracil cannot be
CC       incorporated into DNA. {ECO:0000256|ARBA:ARBA00003495}.
CC   -!- SIMILARITY: Belongs to the dUTPase family.
CC       {ECO:0000256|ARBA:ARBA00006581}.
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DR   EMBL; EF101928; ABT16634.1; -; Genomic_DNA.
DR   RefSeq; YP_001426981.1; NC_008724.1.
DR   GeneID; 5470801; -.
DR   KEGG; vg:5470801; -.
DR   OrthoDB; 12539at10239; -.
DR   Proteomes; UP000202420; Genome.
DR   GO; GO:0004170; F:dUTP diphosphatase activity; IEA:UniProtKB-EC.
DR   GO; GO:0000287; F:magnesium ion binding; IEA:InterPro.
DR   GO; GO:0006226; P:dUMP biosynthetic process; IEA:InterPro.
DR   GO; GO:0046081; P:dUTP catabolic process; IEA:InterPro.
DR   CDD; cd07557; trimeric_dUTPase; 1.
DR   Gene3D; 2.70.40.10; -; 1.
DR   InterPro; IPR008181; dUTPase.
DR   InterPro; IPR029054; dUTPase-like.
DR   InterPro; IPR036157; dUTPase-like_sf.
DR   InterPro; IPR033704; dUTPase_trimeric.
DR   NCBIfam; TIGR00576; dut; 1.
DR   PANTHER; PTHR11241; DEOXYURIDINE 5'-TRIPHOSPHATE NUCLEOTIDOHYDROLASE; 1.
DR   PANTHER; PTHR11241:SF0; DEOXYURIDINE 5'-TRIPHOSPHATE NUCLEOTIDOHYDROLASE; 1.
DR   Pfam; PF00692; dUTPase; 1.
DR   SUPFAM; SSF51283; dUTPase-like; 1.
PE   3: Inferred from homology;
KW   Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW   Reference proteome {ECO:0000313|Proteomes:UP000202420}.
FT   DOMAIN          35..161
FT                   /note="dUTPase-like"
FT                   /evidence="ECO:0000259|Pfam:PF00692"
SQ   SEQUENCE   162 AA;  17400 MW;  C0BCFA7510ABCD0D CRC64;
     MRQYVHIVSP VVMSWRGKCI VTMFSLFVKK LDESAVVPTR GTALSAGYDL SSVADVVVPS
     LGRVAVPTGL AIKVPANTYG RIAPRSGLAF KHGIDVLAGV VDADYRAEVK VILYNTSGVD
     YEIKKGDRIA QLVIEKIEML DVAVVDDLEE TSRTGGFGST GR
//