ID A7MBF3_BOVIN Unreviewed; 309 AA.
AC A7MBF3;
DT 02-OCT-2007, integrated into UniProtKB/TrEMBL.
DT 02-OCT-2007, sequence version 1.
DT 27-MAR-2024, entry version 108.
DE SubName: Full=STYXL1 protein {ECO:0000313|EMBL:AAI51532.1};
DE SubName: Full=Serine/threonine/tyrosine interacting like 1 {ECO:0000313|Ensembl:ENSBTAP00000012447.4};
GN Name=STYXL1 {ECO:0000313|EMBL:AAI51532.1,
GN ECO:0000313|Ensembl:ENSBTAP00000012447.4,
GN ECO:0000313|VGNC:VGNC:35453};
OS Bos taurus (Bovine).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae;
OC Bovinae; Bos.
OX NCBI_TaxID=9913 {ECO:0000313|EMBL:AAI51532.1};
RN [1] {ECO:0000313|EMBL:AAI51532.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=Hereford {ECO:0000313|EMBL:AAI51532.1};
RC TISSUE=Kidney {ECO:0000313|EMBL:AAI51532.1};
RA Moore S., Alexander L., Brownstein M., Guan L., Lobo S., Meng Y.,
RA Tanaguchi M., Wang Z., Yu J., Prange C., Schreiber K., Shenmen C.,
RA Wagner L., Bala M., Barbazuk S., Barber S., Babakaiff R., Beland J.,
RA Chun E., Del Rio L., Gibson S., Hanson R., Kirkpatrick R., Liu J.,
RA Matsuo C., Mayo M., Santos R.R., Stott J., Tsai M., Wong D., Siddiqui A.,
RA Holt R., Jones S.J., Marra M.A.;
RL Submitted (JUL-2007) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSBTAP00000012447.4, ECO:0000313|Proteomes:UP000009136}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Hereford {ECO:0000313|Ensembl:ENSBTAP00000012447.4,
RC ECO:0000313|Proteomes:UP000009136};
RA Rosen B.D., Bickhart D.M., Koren S., Schnabel R.D., Hall R., Zimin A.,
RA Dreischer C., Schultheiss S., Schroeder S.G., Elsik C.G., Couldrey C.,
RA Liu G.E., Van Tassell C.P., Phillippy A.M., Smith T.P.L., Medrano J.F.;
RT "ARS-UCD1.2.";
RL Submitted (MAR-2018) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|Ensembl:ENSBTAP00000012447.4}
RP IDENTIFICATION.
RC STRAIN=Hereford {ECO:0000313|Ensembl:ENSBTAP00000012447.4};
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR EMBL; BC151531; AAI51532.1; -; mRNA.
DR RefSeq; NP_001095438.1; NM_001101968.2.
DR RefSeq; XP_005225150.1; XM_005225093.3.
DR RefSeq; XP_015315921.1; XM_015460435.1.
DR RefSeq; XP_015315922.1; XM_015460436.1.
DR STRING; 9913.ENSBTAP00000012447; -.
DR PaxDb; 9913-ENSBTAP00000012447; -.
DR Ensembl; ENSBTAT00000012447.5; ENSBTAP00000012447.4; ENSBTAG00000009461.5.
DR GeneID; 513107; -.
DR KEGG; bta:513107; -.
DR CTD; 51657; -.
DR VEuPathDB; HostDB:ENSBTAG00000009461; -.
DR VGNC; VGNC:35453; STYXL1.
DR eggNOG; KOG1716; Eukaryota.
DR GeneTree; ENSGT00390000010113; -.
DR HOGENOM; CLU_027074_1_1_1; -.
DR OMA; RFCVVYD; -.
DR TreeFam; TF352452; -.
DR Proteomes; UP000009136; Chromosome 25.
DR Bgee; ENSBTAG00000009461; Expressed in semen and 103 other cell types or tissues.
DR GO; GO:0005739; C:mitochondrion; IBA:GO_Central.
DR GO; GO:0019903; F:protein phosphatase binding; IBA:GO_Central.
DR GO; GO:0004864; F:protein phosphatase inhibitor activity; IBA:GO_Central.
DR GO; GO:0008138; F:protein tyrosine/serine/threonine phosphatase activity; IEA:InterPro.
DR GO; GO:0001691; F:pseudophosphatase activity; IBA:GO_Central.
DR GO; GO:0016311; P:dephosphorylation; IEA:InterPro.
DR GO; GO:0062030; P:negative regulation of stress granule assembly; IBA:GO_Central.
DR GO; GO:2001244; P:positive regulation of intrinsic apoptotic signaling pathway; IBA:GO_Central.
DR GO; GO:0010976; P:positive regulation of neuron projection development; IEA:Ensembl.
DR CDD; cd14517; DSP_STYXL1; 1.
DR Gene3D; 3.90.190.10; Protein tyrosine phosphatase superfamily; 1.
DR Gene3D; 3.40.250.10; Rhodanese-like domain; 1.
DR InterPro; IPR000340; Dual-sp_phosphatase_cat-dom.
DR InterPro; IPR029021; Prot-tyrosine_phosphatase-like.
DR InterPro; IPR001763; Rhodanese-like_dom.
DR InterPro; IPR036873; Rhodanese-like_dom_sf.
DR InterPro; IPR020422; TYR_PHOSPHATASE_DUAL_dom.
DR PANTHER; PTHR46659; SERINE/THREONINE/TYROSINE-INTERACTING-LIKE PROTEIN 1; 1.
DR PANTHER; PTHR46659:SF1; SERINE_THREONINE_TYROSINE-INTERACTING-LIKE PROTEIN 1; 1.
DR Pfam; PF00782; DSPc; 1.
DR Pfam; PF00581; Rhodanese; 1.
DR SMART; SM00195; DSPc; 1.
DR SMART; SM00450; RHOD; 1.
DR SUPFAM; SSF52799; (Phosphotyrosine protein) phosphatases II; 1.
DR SUPFAM; SSF52821; Rhodanese/Cell cycle control phosphatase; 1.
DR PROSITE; PS50054; TYR_PHOSPHATASE_DUAL; 1.
PE 2: Evidence at transcript level;
KW Reference proteome {ECO:0000313|Proteomes:UP000009136}.
FT DOMAIN 155..298
FT /note="Tyrosine-protein phosphatase"
FT /evidence="ECO:0000259|PROSITE:PS50054"
SQ SEQUENCE 309 AA; 35367 MW; 1CDC333CF3655A2A CRC64;
MTGLVLCEPT ELYNILNQVT KLSRLTEPNY LCLLDVRSKR EYDESHVITA LLVKKRAGKY
LIPESVDLEC VEYCVVYDNN TISLELMLKD DSTDDGKHRI VLGAAVECGR ALTHLTRHPV
LILRGGYELF SAMYHFFRTQ KIIWMPQELD AFQPYPIEIM PGRIYLGNFK QACDPKIQKD
LKISAHVNIS METGPFFVGD ADKLLHIQIE DSLEANITPF LRHLCHFIDI HLELNSVILV
FSTLGISRSC AAILAYLMHW NGQTLKKSWA YLKKCKNNMR PNRALVAQLS EWEKVVLGDI
VTDIQNPPY
//
