ID A7MLL6_CROS8 Unreviewed; 420 AA.
AC A7MLL6;
DT 02-OCT-2007, integrated into UniProtKB/TrEMBL.
DT 02-OCT-2007, sequence version 1.
DT 27-MAR-2024, entry version 93.
DE RecName: Full=Fructuronate reductase {ECO:0008006|Google:ProtNLM};
GN OrderedLocusNames=ESA_01067 {ECO:0000313|EMBL:ABU76335.1};
OS Cronobacter sakazakii (strain ATCC BAA-894) (Enterobacter sakazakii).
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
OC Enterobacteriaceae; Cronobacter.
OX NCBI_TaxID=290339 {ECO:0000313|EMBL:ABU76335.1, ECO:0000313|Proteomes:UP000000260};
RN [1] {ECO:0000313|EMBL:ABU76335.1, ECO:0000313|Proteomes:UP000000260}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC BAA-894 {ECO:0000313|EMBL:ABU76335.1,
RC ECO:0000313|Proteomes:UP000000260};
RX PubMed=20221447; DOI=10.1371/journal.pone.0009556;
RA Kucerova E., Clifton S.W., Xia X.Q., Long F., Porwollik S., Fulton L.,
RA Fronick C., Minx P., Kyung K., Warren W., Fulton R., Feng D., Wollam A.,
RA Shah N., Bhonagiri V., Nash W.E., Hallsworth-Pepin K., Wilson R.K.,
RA McClelland M., Forsythe S.J.;
RT "Genome sequence of Cronobacter sakazakii BAA-894 and comparative genomic
RT hybridization analysis with other Cronobacter species.";
RL PLoS ONE 5:E9556-E9556(2010).
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DR EMBL; CP000783; ABU76335.1; -; Genomic_DNA.
DR AlphaFoldDB; A7MLL6; -.
DR KEGG; esa:ESA_01067; -.
DR HOGENOM; CLU_027324_0_1_6; -.
DR Proteomes; UP000000260; Chromosome.
DR GO; GO:0016616; F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor; IEA:UniProt.
DR GO; GO:0019594; P:mannitol metabolic process; IEA:InterPro.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR InterPro; IPR008927; 6-PGluconate_DH-like_C_sf.
DR InterPro; IPR013328; 6PGD_dom2.
DR InterPro; IPR000669; Mannitol_DH.
DR InterPro; IPR013118; Mannitol_DH_C.
DR InterPro; IPR023027; Mannitol_DH_CS.
DR InterPro; IPR013131; Mannitol_DH_N.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR PANTHER; PTHR43362:SF1; MANNITOL DEHYDROGENASE 2-RELATED; 1.
DR PANTHER; PTHR43362; MANNITOL DEHYDROGENASE DSF1-RELATED; 1.
DR Pfam; PF01232; Mannitol_dh; 1.
DR Pfam; PF08125; Mannitol_dh_C; 1.
DR PRINTS; PR00084; MTLDHDRGNASE.
DR SUPFAM; SSF48179; 6-phosphogluconate dehydrogenase C-terminal domain-like; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
DR PROSITE; PS00974; MANNITOL_DHGENASE; 1.
PE 4: Predicted;
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW Reference proteome {ECO:0000313|Proteomes:UP000000260}.
FT DOMAIN 2..120
FT /note="Mannitol dehydrogenase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF01232"
FT DOMAIN 148..392
FT /note="Mannitol dehydrogenase C-terminal"
FT /evidence="ECO:0000259|Pfam:PF08125"
SQ SEQUENCE 420 AA; 46317 MW; 4C02DCECA47522B7 CRC64;
MSALRAQDHL YTVLEKGADG NQAIIIGAVN ECLNAKLDGM DAIIEKFCEP QVAIVSLTIT
EKGYCIDPAT GQLDTQNSRI AHDLENPHQP QSAPGLLVEA LHRRRERGHA PFTVLSCDNI
PDNGHVVREA VLGMAHQRDP ALAQWIADHV TFPGTMVDRI VPAATPESLA EIADALGVAD
PCAISCEPFI QWVIEDNFVA GRPAWEDAGV QMVDDVLPWE QMKLRMLNGS HSFLAYLGYL
SGYAHISDCM NDTHFRDAAR QLMLREQAPT LRITGVDLTG YADSLITRFA NPALKHRTWQ
IAMDGSQKLP QRMLDSVRWH LQHGGEWSLL ALGVAGWMRY VSGVDDRGQP VDVRDPLAEK
IAALVQSSSE DERVGALLTL KEVFGEDLPQ HPLFIHTLNA AWQSLCRLGA KEAVARLARR
//
