ID A7RF43_NEMVE Unreviewed; 359 AA.
AC A7RF43;
DT 02-OCT-2007, integrated into UniProtKB/TrEMBL.
DT 02-OCT-2007, sequence version 1.
DT 27-MAR-2024, entry version 71.
DE RecName: Full=Spondin domain-containing protein {ECO:0000259|PROSITE:PS51020};
DE Flags: Fragment;
GN ORFNames=NEMVEDRAFT_v1g79471 {ECO:0000313|EMBL:EDO49895.1};
OS Nematostella vectensis (Starlet sea anemone).
OC Eukaryota; Metazoa; Cnidaria; Anthozoa; Hexacorallia; Actiniaria;
OC Edwardsiidae; Nematostella.
OX NCBI_TaxID=45351 {ECO:0000313|EMBL:EDO49895.1, ECO:0000313|Proteomes:UP000001593};
RN [1] {ECO:0000313|EMBL:EDO49895.1, ECO:0000313|Proteomes:UP000001593}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CH2 X CH6 {ECO:0000313|Proteomes:UP000001593};
RX PubMed=17615350; DOI=10.1126/science.1139158;
RA Putnam N.H., Srivastava M., Hellsten U., Dirks B., Chapman J., Salamov A.,
RA Terry A., Shapiro H., Lindquist E., Kapitonov V.V., Jurka J.,
RA Genikhovich G., Grigoriev I.V., Lucas S.M., Steele R.E., Finnerty J.R.,
RA Technau U., Martindale M.Q., Rokhsar D.S.;
RT "Sea anemone genome reveals ancestral eumetazoan gene repertoire and
RT genomic organization.";
RL Science 317:86-94(2007).
CC -!- SUBCELLULAR LOCATION: Secreted, extracellular space, extracellular
CC matrix {ECO:0000256|ARBA:ARBA00004498}.
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DR EMBL; DS469507; EDO49895.1; -; Genomic_DNA.
DR RefSeq; XP_001641958.1; XM_001641908.1.
DR AlphaFoldDB; A7RF43; -.
DR STRING; 45351.A7RF43; -.
DR EnsemblMetazoa; EDO49895; EDO49895; NEMVEDRAFT_v1g79471.
DR eggNOG; KOG3539; Eukaryota.
DR HOGENOM; CLU_034407_1_0_1; -.
DR InParanoid; A7RF43; -.
DR OMA; NSCAHID; -.
DR PhylomeDB; A7RF43; -.
DR Proteomes; UP000001593; Unassembled WGS sequence.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-KW.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.
DR Gene3D; 2.60.40.2130; F-spondin domain; 1.
DR Gene3D; 2.20.100.10; Thrombospondin type-1 (TSP1) repeat; 2.
DR InterPro; IPR009465; Spondin_N.
DR InterPro; IPR038678; Spondin_N_sf.
DR InterPro; IPR000884; TSP1_rpt.
DR InterPro; IPR036383; TSP1_rpt_sf.
DR InterPro; IPR044004; TSP1_spondin_dom.
DR NCBIfam; NF038123; NF038123_dom; 1.
DR PANTHER; PTHR11311; SPONDIN; 1.
DR PANTHER; PTHR11311:SF32; TSP1_SPONDIN DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF06468; Spond_N; 1.
DR Pfam; PF19028; TSP1_spondin; 2.
DR SMART; SM00209; TSP1; 2.
DR SUPFAM; SSF82895; TSP-1 type 1 repeat; 2.
DR PROSITE; PS51020; SPONDIN; 1.
DR PROSITE; PS50092; TSP1; 2.
PE 4: Predicted;
KW Cell adhesion {ECO:0000256|ARBA:ARBA00022889};
KW Extracellular matrix {ECO:0000256|ARBA:ARBA00022530};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000001593};
KW Secreted {ECO:0000256|ARBA:ARBA00022525}.
FT DOMAIN 1..184
FT /note="Spondin"
FT /evidence="ECO:0000259|PROSITE:PS51020"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:EDO49895.1"
FT NON_TER 359
FT /evidence="ECO:0000313|EMBL:EDO49895.1"
SQ SEQUENCE 359 AA; 40523 MW; 4498FF17A75875C5 CRC64;
ECCACGKATY KLTFKGKWSQ ETHARHHPGP MARWSPLIGC SHSNKYVMWR YGGIASRAVQ
MMSEWGATEY LDEEMRNQQE NVMSIIQTPS LWYGVGESSA VFRVDSTRHL LSMISRMIPS
PDWNVGVDRV NLCTTNCTWK HEETIDLIPW DAGTDDGITF KSPNARSTPK QPISRITTRL
HDHPRASFYL NTNDQIRPFA SLKLERLAVS GGCSNDAHIA PKNPYPPKSA RIDCQLTHWS
KWTSCSVTCG VGEQIRGRDI IRVPEHDGIP CPNLYEHRPC ARQRCSSTKK CEVTPWSAWS
SCRGSCGVGR KVRTRRIIRQ SSLSGMTCPS LVKKRKCKLS PCHCVVTSWS VWSTCSRDC
//
