ID A7RFU2_NEMVE Unreviewed; 407 AA.
AC A7RFU2;
DT 02-OCT-2007, integrated into UniProtKB/TrEMBL.
DT 02-OCT-2007, sequence version 1.
DT 27-MAR-2024, entry version 61.
DE RecName: Full=Major facilitator superfamily domain-containing protein 12 {ECO:0008006|Google:ProtNLM};
GN ORFNames=NEMVEDRAFT_v1g80169 {ECO:0000313|EMBL:EDO49663.1};
OS Nematostella vectensis (Starlet sea anemone).
OC Eukaryota; Metazoa; Cnidaria; Anthozoa; Hexacorallia; Actiniaria;
OC Edwardsiidae; Nematostella.
OX NCBI_TaxID=45351 {ECO:0000313|EMBL:EDO49663.1, ECO:0000313|Proteomes:UP000001593};
RN [1] {ECO:0000313|EMBL:EDO49663.1, ECO:0000313|Proteomes:UP000001593}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CH2 X CH6 {ECO:0000313|Proteomes:UP000001593};
RX PubMed=17615350; DOI=10.1126/science.1139158;
RA Putnam N.H., Srivastava M., Hellsten U., Dirks B., Chapman J., Salamov A.,
RA Terry A., Shapiro H., Lindquist E., Kapitonov V.V., Jurka J.,
RA Genikhovich G., Grigoriev I.V., Lucas S.M., Steele R.E., Finnerty J.R.,
RA Technau U., Martindale M.Q., Rokhsar D.S.;
RT "Sea anemone genome reveals ancestral eumetazoan gene repertoire and
RT genomic organization.";
RL Science 317:86-94(2007).
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DR EMBL; DS469508; EDO49663.1; -; Genomic_DNA.
DR RefSeq; XP_001641726.1; XM_001641676.1.
DR AlphaFoldDB; A7RFU2; -.
DR EnsemblMetazoa; EDO49663; EDO49663; NEMVEDRAFT_v1g80169.
DR eggNOG; KOG4830; Eukaryota.
DR HOGENOM; CLU_030068_1_1_1; -.
DR InParanoid; A7RFU2; -.
DR PhylomeDB; A7RFU2; -.
DR Proteomes; UP000001593; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0015293; F:symporter activity; IEA:InterPro.
DR GO; GO:0008643; P:carbohydrate transport; IEA:InterPro.
DR GO; GO:0071702; P:organic substance transport; IBA:GO_Central.
DR CDD; cd17491; MFS_MFSD12; 1.
DR Gene3D; 1.20.1250.20; MFS general substrate transporter like domains; 2.
DR InterPro; IPR039672; MFS_2.
DR InterPro; IPR036259; MFS_trans_sf.
DR PANTHER; PTHR11328; MAJOR FACILITATOR SUPERFAMILY DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR11328:SF28; MAJOR FACILITATOR SUPERFAMILY DOMAIN-CONTAINING PROTEIN 12; 1.
DR Pfam; PF13347; MFS_2; 1.
DR SUPFAM; SSF103473; MFS general substrate transporter; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000001593};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 76..92
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 112..133
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 153..170
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 190..216
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 286..305
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 317..336
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 342..365
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 377..398
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:EDO49663.1"
SQ SEQUENCE 407 AA; 45992 MW; C5323EE3806E293A CRC64;
RFAYGVGHVF NDLCIQAWFS YSLIYFTKVM GLSAVNAGYI FLASQLADAF STPFIGYLCD
RQITKIVGER YGNKKIWHLF GCVGIAIVWP FLFSPCLMCD ENTEEWQKTT YFGILTLIFN
ICWPMVEISH LSLMPHVARR TKDAIELSAI RSAMKLGCGV YVYVVTWILL KDNKETQIDA
SLSRFKSTPV FFFFQYQTII VLITGGIFAL VFHWGVDETT RHREMQNGKK YPPSLLGVKK
SIKEWFKSAD FYVMMVIYFT TQNTTNLIQT YFPIYLTETM HFPKEAIAYF PLLILVFGII
ASAAVKPLTK KFSNRVLYCA SAVVVIASEA WMFFNPQESR DAIYAPTILL GCGVSIMVVT
SLAMVSDLIG DDKESSGVVY SVMSFVDKLS LGLIVLGLQE NTPENHG
//
