ID A7RFY4_NEMVE Unreviewed; 340 AA.
AC A7RFY4;
DT 02-OCT-2007, integrated into UniProtKB/TrEMBL.
DT 02-OCT-2007, sequence version 1.
DT 24-JAN-2024, entry version 76.
DE RecName: Full=C2 domain-containing protein {ECO:0000259|PROSITE:PS50004};
DE Flags: Fragment;
GN ORFNames=NEMVEDRAFT_v1g79980 {ECO:0000313|EMBL:EDO49802.1};
OS Nematostella vectensis (Starlet sea anemone).
OC Eukaryota; Metazoa; Cnidaria; Anthozoa; Hexacorallia; Actiniaria;
OC Edwardsiidae; Nematostella.
OX NCBI_TaxID=45351 {ECO:0000313|EMBL:EDO49802.1, ECO:0000313|Proteomes:UP000001593};
RN [1] {ECO:0000313|EMBL:EDO49802.1, ECO:0000313|Proteomes:UP000001593}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CH2 X CH6 {ECO:0000313|Proteomes:UP000001593};
RX PubMed=17615350; DOI=10.1126/science.1139158;
RA Putnam N.H., Srivastava M., Hellsten U., Dirks B., Chapman J., Salamov A.,
RA Terry A., Shapiro H., Lindquist E., Kapitonov V.V., Jurka J.,
RA Genikhovich G., Grigoriev I.V., Lucas S.M., Steele R.E., Finnerty J.R.,
RA Technau U., Martindale M.Q., Rokhsar D.S.;
RT "Sea anemone genome reveals ancestral eumetazoan gene repertoire and
RT genomic organization.";
RL Science 317:86-94(2007).
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DR EMBL; DS469508; EDO49802.1; -; Genomic_DNA.
DR RefSeq; XP_001641865.1; XM_001641815.1.
DR AlphaFoldDB; A7RFY4; -.
DR STRING; 45351.A7RFY4; -.
DR eggNOG; KOG1028; Eukaryota.
DR HOGENOM; CLU_667863_0_0_1; -.
DR InParanoid; A7RFY4; -.
DR OMA; KMDPAVM; -.
DR PhylomeDB; A7RFY4; -.
DR Proteomes; UP000001593; Unassembled WGS sequence.
DR GO; GO:0070382; C:exocytic vesicle; IBA:GO_Central.
DR GO; GO:0005886; C:plasma membrane; IBA:GO_Central.
DR GO; GO:0005509; F:calcium ion binding; IBA:GO_Central.
DR GO; GO:0005544; F:calcium-dependent phospholipid binding; IBA:GO_Central.
DR GO; GO:0030276; F:clathrin binding; IBA:GO_Central.
DR GO; GO:0001786; F:phosphatidylserine binding; IBA:GO_Central.
DR GO; GO:0000149; F:SNARE binding; IBA:GO_Central.
DR GO; GO:0017156; P:calcium-ion regulated exocytosis; IBA:GO_Central.
DR GO; GO:0071277; P:cellular response to calcium ion; IBA:GO_Central.
DR GO; GO:0017158; P:regulation of calcium ion-dependent exocytosis; IBA:GO_Central.
DR GO; GO:0014059; P:regulation of dopamine secretion; IBA:GO_Central.
DR CDD; cd00030; C2; 1.
DR Gene3D; 2.60.40.150; C2 domain; 2.
DR InterPro; IPR000008; C2_dom.
DR InterPro; IPR035892; C2_domain_sf.
DR InterPro; IPR001565; Synaptotagmin.
DR PANTHER; PTHR45716; BITESIZE, ISOFORM I; 1.
DR PANTHER; PTHR45716:SF2; BITESIZE, ISOFORM I; 1.
DR Pfam; PF00168; C2; 2.
DR PRINTS; PR00360; C2DOMAIN.
DR PRINTS; PR00399; SYNAPTOTAGMN.
DR SMART; SM00239; C2; 2.
DR SUPFAM; SSF49562; C2 domain (Calcium/lipid-binding domain, CaLB); 2.
DR PROSITE; PS50004; C2; 2.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000001593};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT DOMAIN 29..151
FT /note="C2"
FT /evidence="ECO:0000259|PROSITE:PS50004"
FT DOMAIN 161..270
FT /note="C2"
FT /evidence="ECO:0000259|PROSITE:PS50004"
FT NON_TER 340
FT /evidence="ECO:0000313|EMBL:EDO49802.1"
SQ SEQUENCE 340 AA; 38841 MW; 80F77B18B297DED0 CRC64;
PYQLASTDLI KEMYKRMNPT VTQADSGDIK GDIEMSLKYN HREQLLLVKV IRARDLVPRD
LNGKSDPYVV LELVPDRLEE GTKKTRFKQK TLNPVFNEIF QFKVPHNNLT DTKLCATIWD
HDFFGEDDFN GEAVVDLSRV NFNNGTHTDW FMLQLQTDFS ITGELDVTVE YLEPDTLAVT
IHKATNLKSS NSMANTSDAY VRCSVIPGTL NPEFAEIFEF EVPREELDHR AIQFHVFGKE
TLVQDVSLGQ AYFDLKSLDL DEPERTSLPL ADLKNECLKR AEWAQNAVAQ EFREAMYAHA
MYKHPTFIYS MHNKGRKMYS VSSRNAGSSA KVFLVNGIPV
//
