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Database: UniProt
Entry: A7RH68_NEMVE
LinkDB: A7RH68_NEMVE
Original site: A7RH68_NEMVE 
ID   A7RH68_NEMVE            Unreviewed;       571 AA.
AC   A7RH68;
DT   02-OCT-2007, integrated into UniProtKB/TrEMBL.
DT   02-OCT-2007, sequence version 1.
DT   28-FEB-2018, entry version 66.
DE   SubName: Full=Predicted protein {ECO:0000313|EMBL:EDO49302.1};
GN   ORFNames=v1g197088 {ECO:0000313|EMBL:EDO49302.1};
OS   Nematostella vectensis (Starlet sea anemone).
OC   Eukaryota; Metazoa; Cnidaria; Anthozoa; Hexacorallia; Actiniaria;
OC   Edwardsiidae; Nematostella.
OX   NCBI_TaxID=45351 {ECO:0000313|Proteomes:UP000001593};
RN   [1] {ECO:0000313|EMBL:EDO49302.1, ECO:0000313|Proteomes:UP000001593}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CH2 X CH6 {ECO:0000313|Proteomes:UP000001593};
RX   PubMed=17615350; DOI=10.1126/science.1139158;
RA   Putnam N.H., Srivastava M., Hellsten U., Dirks B., Chapman J.,
RA   Salamov A., Terry A., Shapiro H., Lindquist E., Kapitonov V.V.,
RA   Jurka J., Genikhovich G., Grigoriev I.V., Lucas S.M., Steele R.E.,
RA   Finnerty J.R., Technau U., Martindale M.Q., Rokhsar D.S.;
RT   "Sea anemone genome reveals ancestral eumetazoan gene repertoire and
RT   genomic organization.";
RL   Science 317:86-94(2007).
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DR   EMBL; DS469510; EDO49302.1; -; Genomic_DNA.
DR   RefSeq; XP_001641365.1; XM_001641315.1.
DR   STRING; 45351.NEMVEDRAFT_v1g197088-PA; -.
DR   EnsemblMetazoa; EDO49302; EDO49302; NEMVEDRAFT_v1g197088.
DR   GeneID; 5521447; -.
DR   KEGG; nve:NEMVE_v1g197088; -.
DR   eggNOG; KOG3609; Eukaryota.
DR   eggNOG; ENOG410XQ0Y; LUCA.
DR   InParanoid; A7RH68; -.
DR   OrthoDB; EOG09370Q7F; -.
DR   Proteomes; UP000001593; Unassembled WGS sequence.
DR   GO; GO:0005887; C:integral component of plasma membrane; IBA:GO_Central.
DR   GO; GO:0015279; F:store-operated calcium channel activity; IBA:GO_Central.
DR   GO; GO:0006828; P:manganese ion transport; IBA:GO_Central.
DR   GO; GO:0051480; P:regulation of cytosolic calcium ion concentration; IBA:GO_Central.
DR   Gene3D; 1.25.40.20; -; 1.
DR   InterPro; IPR036770; Ankyrin_rpt-contain_sf.
DR   InterPro; IPR005821; Ion_trans_dom.
DR   InterPro; IPR002153; TRPC_channel.
DR   PANTHER; PTHR10117; PTHR10117; 1.
DR   Pfam; PF00520; Ion_trans; 1.
DR   SUPFAM; SSF48403; SSF48403; 1.
PE   4: Predicted;
KW   Complete proteome {ECO:0000313|Proteomes:UP000001593};
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000001593};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    340    358       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    374    393       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    400    421       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    441    462       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    483    504       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    524    542       Helical. {ECO:0000256|SAM:Phobius}.
FT   DOMAIN      386    546       Ion_trans. {ECO:0000259|Pfam:PF00520}.
SQ   SEQUENCE   571 AA;  66621 MW;  4D3EDB943D2017E6 CRC64;
     MAASSHFEHK EMDHLSYSAD EQLLFDLVLN EDVEGVRSFF DLRPDFLFRT RDFVTRALLS
     DTIDLNRGDI LKIFLDEQAR IGGALFNAVR KGSKDCVQTM LPYISSKRGD IGPEDVKPGA
     FVSPLMLAVH LEKFDIIELF LSKGYRVLEP HDDDDEDDDD EQLNRTNVGL ELSSELSFNL
     RVNAYRALAS PLYISYFFIM NPDALHPIFH VLELNKKLKN QMYRDFEFNN DYKQISKDCQ
     RFAVDLLEQC RTTDETNVLL DVYPEIQRVY EKDKKHIEGS HTAFKELSML NLAIRNDMNE
     LVAHPQSQLR LDKILYHGLY MFKREPRVWR YRSWYTGKLF WLRHTLLLPF LALFYIIAPD
     CRISNVLKTP MVKFYSHTGA FVLFAIALAV SSFEDHFTDY TLIPVLIDWG TLLFVLGLFL
     QEVKDLYFQG AFRYIRQWWN IISLLMVVLF LISYSLRLTA YLSPQTSPPH LKNLAVRSSQ
     LSLLANSFFA FAMVFSFIHL TNFLQVSDVF GPLQLSLYML FADLIKFFVF FFVLFLAFGL
     SLRKLYSHYK TSQQHFVNIT RPVDTNHPYS A
//
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