ID A7RJM2_NEMVE Unreviewed; 162 AA.
AC A7RJM2;
DT 02-OCT-2007, integrated into UniProtKB/TrEMBL.
DT 02-OCT-2007, sequence version 1.
DT 27-MAR-2024, entry version 94.
DE RecName: Full=H15 domain-containing protein {ECO:0000259|PROSITE:PS51504};
GN ORFNames=NEMVEDRAFT_v1g198083 {ECO:0000313|EMBL:EDO48286.1};
OS Nematostella vectensis (Starlet sea anemone).
OC Eukaryota; Metazoa; Cnidaria; Anthozoa; Hexacorallia; Actiniaria;
OC Edwardsiidae; Nematostella.
OX NCBI_TaxID=45351 {ECO:0000313|EMBL:EDO48286.1, ECO:0000313|Proteomes:UP000001593};
RN [1] {ECO:0000313|EMBL:EDO48286.1, ECO:0000313|Proteomes:UP000001593}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CH2 X CH6 {ECO:0000313|Proteomes:UP000001593};
RX PubMed=17615350; DOI=10.1126/science.1139158;
RA Putnam N.H., Srivastava M., Hellsten U., Dirks B., Chapman J., Salamov A.,
RA Terry A., Shapiro H., Lindquist E., Kapitonov V.V., Jurka J.,
RA Genikhovich G., Grigoriev I.V., Lucas S.M., Steele R.E., Finnerty J.R.,
RA Technau U., Martindale M.Q., Rokhsar D.S.;
RT "Sea anemone genome reveals ancestral eumetazoan gene repertoire and
RT genomic organization.";
RL Science 317:86-94(2007).
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|RuleBase:RU003894}.
CC -!- SIMILARITY: Belongs to the histone H1/H5 family.
CC {ECO:0000256|RuleBase:RU003894}.
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DR EMBL; DS469514; EDO48286.1; -; Genomic_DNA.
DR RefSeq; XP_001640349.1; XM_001640299.1.
DR AlphaFoldDB; A7RJM2; -.
DR STRING; 45351.A7RJM2; -.
DR EnsemblMetazoa; EDO48286; EDO48286; NEMVEDRAFT_v1g198083.
DR GeneID; 5520639; -.
DR KEGG; nve:5520639; -.
DR eggNOG; KOG4012; Eukaryota.
DR HOGENOM; CLU_052897_1_1_1; -.
DR InParanoid; A7RJM2; -.
DR OMA; KTEYSAN; -.
DR OrthoDB; 5363206at2759; -.
DR Proteomes; UP000001593; Unassembled WGS sequence.
DR GO; GO:0000786; C:nucleosome; IEA:InterPro.
DR GO; GO:0005634; C:nucleus; IBA:GO_Central.
DR GO; GO:0003690; F:double-stranded DNA binding; IBA:GO_Central.
DR GO; GO:0031492; F:nucleosomal DNA binding; IBA:GO_Central.
DR GO; GO:0030527; F:structural constituent of chromatin; IEA:InterPro.
DR GO; GO:0030261; P:chromosome condensation; IBA:GO_Central.
DR GO; GO:0045910; P:negative regulation of DNA recombination; IBA:GO_Central.
DR GO; GO:0006334; P:nucleosome assembly; IEA:InterPro.
DR CDD; cd00073; H15; 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR005819; H1/H5.
DR InterPro; IPR005818; Histone_H1/H5_H15.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR11467; HISTONE H1; 1.
DR PANTHER; PTHR11467:SF154; HISTONE H1.0; 1.
DR Pfam; PF00538; Linker_histone; 1.
DR PRINTS; PR00624; HISTONEH5.
DR SMART; SM00526; H15; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS51504; H15; 1.
PE 3: Inferred from homology;
KW Chromosome {ECO:0000256|RuleBase:RU003894};
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125, ECO:0000256|RuleBase:RU003894};
KW Nucleus {ECO:0000256|RuleBase:RU003894};
KW Reference proteome {ECO:0000313|Proteomes:UP000001593}.
FT DOMAIN 18..91
FT /note="H15"
FT /evidence="ECO:0000259|PROSITE:PS51504"
FT REGION 1..21
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 70..162
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..19
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 100..162
FT /note="Basic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 162 AA; 16999 MW; CE3967F5042CD668 CRC64;
MSDEAKPAKA KKPAKPAEHP KYSDMVVAAI GALKERNGSS RQAIEKYIKG NYKVGDGVGV
HLKLALKRMS DKGKLVHTKG VGASGSFKLN KAAVEKPKKA KKPVAKKPKA AKKPAAKKSP
KKAAAKKSPK KAAKKPAAKK PAAKKAAKKP AAKKAAKKPA KK
//
