ID   A7RNC5_NEMVE            Unreviewed;      1111 AA.
AC   A7RNC5;
DT   02-OCT-2007, integrated into UniProtKB/TrEMBL.
DT   02-OCT-2007, sequence version 1.
DT   24-JAN-2024, entry version 68.
DE   RecName: Full=C-Jun-amino-terminal kinase-interacting protein 4 {ECO:0008006|Google:ProtNLM};
GN   ORFNames=NEMVEDRAFT_v1g87399 {ECO:0000313|EMBL:EDO47039.1};
OS   Nematostella vectensis (Starlet sea anemone).
OC   Eukaryota; Metazoa; Cnidaria; Anthozoa; Hexacorallia; Actiniaria;
OC   Edwardsiidae; Nematostella.
OX   NCBI_TaxID=45351 {ECO:0000313|EMBL:EDO47039.1, ECO:0000313|Proteomes:UP000001593};
RN   [1] {ECO:0000313|EMBL:EDO47039.1, ECO:0000313|Proteomes:UP000001593}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CH2 X CH6 {ECO:0000313|Proteomes:UP000001593};
RX   PubMed=17615350; DOI=10.1126/science.1139158;
RA   Putnam N.H., Srivastava M., Hellsten U., Dirks B., Chapman J., Salamov A.,
RA   Terry A., Shapiro H., Lindquist E., Kapitonov V.V., Jurka J.,
RA   Genikhovich G., Grigoriev I.V., Lucas S.M., Steele R.E., Finnerty J.R.,
RA   Technau U., Martindale M.Q., Rokhsar D.S.;
RT   "Sea anemone genome reveals ancestral eumetazoan gene repertoire and
RT   genomic organization.";
RL   Science 317:86-94(2007).
CC   -!- SIMILARITY: Belongs to the JIP scaffold family.
CC       {ECO:0000256|ARBA:ARBA00009866}.
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DR   EMBL; DS469522; EDO47039.1; -; Genomic_DNA.
DR   RefSeq; XP_001639102.1; XM_001639052.1.
DR   AlphaFoldDB; A7RNC5; -.
DR   STRING; 45351.A7RNC5; -.
DR   EnsemblMetazoa; EDO47039; EDO47039; NEMVEDRAFT_v1g87399.
DR   eggNOG; KOG2077; Eukaryota.
DR   HOGENOM; CLU_003841_0_0_1; -.
DR   InParanoid; A7RNC5; -.
DR   OMA; MEYIERT; -.
DR   PhylomeDB; A7RNC5; -.
DR   Proteomes; UP000001593; Unassembled WGS sequence.
DR   GO; GO:0005737; C:cytoplasm; IBA:GO_Central.
DR   GO; GO:0019894; F:kinesin binding; IBA:GO_Central.
DR   GO; GO:0005078; F:MAP-kinase scaffold activity; IBA:GO_Central.
DR   GO; GO:0030159; F:signaling receptor complex adaptor activity; IBA:GO_Central.
DR   GO; GO:0016192; P:vesicle-mediated transport; IBA:GO_Central.
DR   Gene3D; 1.20.58.1770; -; 1.
DR   Gene3D; 1.20.5.1000; arf6 gtpase in complex with a specific effector, jip4; 1.
DR   Gene3D; 2.130.10.10; YVTN repeat-like/Quinoprotein amine dehydrogenase; 1.
DR   InterPro; IPR039911; JIP3/JIP4.
DR   InterPro; IPR032486; JIP_LZII.
DR   InterPro; IPR019143; JNK/Rab-associated_protein-1_N.
DR   InterPro; IPR034743; RH1.
DR   InterPro; IPR034744; RH2.
DR   InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR   InterPro; IPR036322; WD40_repeat_dom_sf.
DR   PANTHER; PTHR13886:SF4; JNK-INTERACTING PROTEIN 3; 1.
DR   PANTHER; PTHR13886; JNK/SAPK-ASSOCIATED PROTEIN; 1.
DR   Pfam; PF16471; JIP_LZII; 1.
DR   Pfam; PF09744; Jnk-SapK_ap_N; 1.
DR   Pfam; PF19056; WD40_2; 1.
DR   SUPFAM; SSF50978; WD40 repeat-like; 1.
DR   PROSITE; PS51776; RH1; 1.
DR   PROSITE; PS51777; RH2; 1.
PE   3: Inferred from homology;
KW   Coiled coil {ECO:0000256|ARBA:ARBA00023054, ECO:0000256|SAM:Coils};
KW   Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW   Reference proteome {ECO:0000313|Proteomes:UP000001593}.
FT   DOMAIN          10..98
FT                   /note="RH1"
FT                   /evidence="ECO:0000259|PROSITE:PS51776"
FT   DOMAIN          428..500
FT                   /note="RH2"
FT                   /evidence="ECO:0000259|PROSITE:PS51777"
FT   REGION          1..20
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          509..541
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          726..774
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          75..183
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          341..410
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COMPBIAS        509..540
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        732..759
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1111 AA;  123143 MW;  72AEF82ABB925C81 CRC64;
     MEVDDDTNEA VYSSGEEGGT TVMSERVSNL ANSIYSEFER MIQKYDQDVV SGLMPLMVSV
     LEQLDSAYGD NNEQLVELEI LSDDNEQLIT QYEREKQLRK LAENRYLEIE DQIEAEKRNA
     EKDIESLEHD NRGLEARIKS YQDHVERLEE RISEMKREYG SLHQRHSEVV QHYMERIERA
     EKRSIASTET PQKGLNRYLH MLKLSSSTGL EKSQGANVDG LDVNNSTCSI SDVDNLPIVS
     AREAANMLTP GSSDVSLTGI SKDAAAILAS TPELSGSNVV TEVARREKGS SSANRPVSLD
     LENLPEGVAA SSLFAELSSE EPDVIGQMDT GADIIAMGRE LENVMKENKE LVTVKNKLET
     QKNDLLKRLE ELSNDKEVMT EELKSLQEVK QRMNIRVTEC EHELKRTKHE AEKATVALKE
     ASVSAAHRKR FTRVEMARVL MERNQYKERL MELQEAVRWT EMIRASKERN LELQQKKKSS
     IWKFFSNLFG PTPRARPNPS TVSIRYNSGE GQGTPPARRH NSLTNLNTGS NMSGGYGSEN
     FDRQRLNERR ERYKQVRAYL NTDLSEGRMQ AYGWSLPAKY SSEVAEGGKS LVSVPVPVYC
     RPLNLSDPGM KIWCAAGVDL SGGYTSDGGA AIGASVFYAD SPGGEDVEIK EAKPSTTWIG
     DLFQLTPVLT PLCISGSSTH SCSKITIIDA NYPQNILDCF VVCTSHLLCI TAVPGASPGD
     YDAASVGDGA RVSSAPQDSQ TCDKQPVSDS PTVTDVSTSE SDRVDARSAD GEGTKMSSVL
     PTMWLGAQSG CVYVHSAISQ WRTCIQSIRL KDSVLSIVHV KGRVLVALAD GTVAIFHRSS
     DGQWNFNNYH LLDLGRPHHS IRCMAMVHDK VWCGYRNKIQ VIHPRTMRVE KTFDAHPRHE
     SQVRQLAWIG DGVWVSIRLD STLRLYNAQT YHHLQDIDIE PYVSKMLGTG KLGFSFVRIT
     SLLLTNDRLW VGTGNGVILS VPLVAARPAR DDGDQQLAVT SSPAKGEGVL SSSFMPYCSM
     VNAQLSFHGH RDSVKFFVAV QGFMKRVSSS QSRNQDMMLV LSGGEGYVDF RLGDGEEAAV
     EDSAGDLISV TLKGQSTSER SHIMVWQVAS N
//