ID A7RNK4_NEMVE Unreviewed; 303 AA.
AC A7RNK4;
DT 02-OCT-2007, integrated into UniProtKB/TrEMBL.
DT 02-OCT-2007, sequence version 1.
DT 27-MAR-2024, entry version 85.
DE SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:EDO46941.1};
GN ORFNames=NEMVEDRAFT_v1g232054 {ECO:0000313|EMBL:EDO46941.1};
OS Nematostella vectensis (Starlet sea anemone).
OC Eukaryota; Metazoa; Cnidaria; Anthozoa; Hexacorallia; Actiniaria;
OC Edwardsiidae; Nematostella.
OX NCBI_TaxID=45351 {ECO:0000313|EMBL:EDO46941.1, ECO:0000313|Proteomes:UP000001593};
RN [1] {ECO:0000313|EMBL:EDO46941.1, ECO:0000313|Proteomes:UP000001593}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CH2 X CH6 {ECO:0000313|Proteomes:UP000001593};
RX PubMed=17615350; DOI=10.1126/science.1139158;
RA Putnam N.H., Srivastava M., Hellsten U., Dirks B., Chapman J., Salamov A.,
RA Terry A., Shapiro H., Lindquist E., Kapitonov V.V., Jurka J.,
RA Genikhovich G., Grigoriev I.V., Lucas S.M., Steele R.E., Finnerty J.R.,
RA Technau U., Martindale M.Q., Rokhsar D.S.;
RT "Sea anemone genome reveals ancestral eumetazoan gene repertoire and
RT genomic organization.";
RL Science 317:86-94(2007).
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DR EMBL; DS469523; EDO46941.1; -; Genomic_DNA.
DR RefSeq; XP_001639004.1; XM_001638954.1.
DR AlphaFoldDB; A7RNK4; -.
DR STRING; 45351.A7RNK4; -.
DR EnsemblMetazoa; EDO46941; EDO46941; NEMVEDRAFT_v1g232054.
DR GeneID; 5519078; -.
DR KEGG; nve:5519078; -.
DR eggNOG; KOG0297; Eukaryota.
DR HOGENOM; CLU_934763_0_0_1; -.
DR InParanoid; A7RNK4; -.
DR OMA; CAHRICE; -.
DR OrthoDB; 3041517at2759; -.
DR PhylomeDB; A7RNK4; -.
DR Proteomes; UP000001593; Unassembled WGS sequence.
DR GO; GO:0031625; F:ubiquitin protein ligase binding; IBA:GO_Central.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR GO; GO:0070534; P:protein K63-linked ubiquitination; IBA:GO_Central.
DR GO; GO:0043122; P:regulation of canonical NF-kappaB signal transduction; IBA:GO_Central.
DR GO; GO:0033209; P:tumor necrosis factor-mediated signaling pathway; IBA:GO_Central.
DR Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 2.
DR InterPro; IPR001841; Znf_RING.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR InterPro; IPR001293; Znf_TRAF.
DR PANTHER; PTHR10131:SF138; MATH DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR10131; TNF RECEPTOR ASSOCIATED FACTOR; 1.
DR SMART; SM00184; RING; 1.
DR SUPFAM; SSF57850; RING/U-box; 1.
DR SUPFAM; SSF49599; TRAF domain-like; 1.
DR PROSITE; PS50089; ZF_RING_2; 1.
DR PROSITE; PS50145; ZF_TRAF; 1.
PE 4: Predicted;
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723, ECO:0000256|PROSITE-
KW ProRule:PRU00207}; Reference proteome {ECO:0000313|Proteomes:UP000001593};
KW Zinc {ECO:0000256|ARBA:ARBA00022833, ECO:0000256|PROSITE-ProRule:PRU00207};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00207}.
FT DOMAIN 18..54
FT /note="RING-type"
FT /evidence="ECO:0000259|PROSITE:PS50089"
FT DOMAIN 120..171
FT /note="TRAF-type"
FT /evidence="ECO:0000259|PROSITE:PS50145"
FT ZN_FING 120..171
FT /note="TRAF-type"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00207"
SQ SEQUENCE 303 AA; 34323 MW; B4EA4C7E65614402 CRC64;
MDSTMYIITG DAPDDFICNV CGTVMLVPVV MPNCGHSCCS SCAKRVNRKC PECREEFGAT
AELRENISLK RIIRRLQAKC KRCPFNGELG LVLDHLCPER ETECTNPSCN VKVKRSALSS
HLQVCPQKMT ECAECQKRMP RALLERHSQY ECFQRMVQCV LCTENVKRDG LNLHLTNCEE
RSRTCGVPGC HFHGNQEQML RHRVSYASGH VELYRTYAER LAHAIAKKST PSVEKLPLRV
ETFLWCTEAF KEKAASACAG QPLTSPTYRS EAGEKWRLVL FVKPYKLYAQ LQSSVAPLNV
NIR
//
