ID A7RPC8_NEMVE Unreviewed; 195 AA.
AC A7RPC8;
DT 02-OCT-2007, integrated into UniProtKB/TrEMBL.
DT 02-OCT-2007, sequence version 1.
DT 27-MAR-2024, entry version 88.
DE RecName: Full=T-box domain-containing protein {ECO:0000259|PROSITE:PS50252};
DE Flags: Fragment;
GN ORFNames=NEMVEDRAFT_v1g88753 {ECO:0000313|EMBL:EDO46664.1};
OS Nematostella vectensis (Starlet sea anemone).
OC Eukaryota; Metazoa; Cnidaria; Anthozoa; Hexacorallia; Actiniaria;
OC Edwardsiidae; Nematostella.
OX NCBI_TaxID=45351 {ECO:0000313|EMBL:EDO46664.1, ECO:0000313|Proteomes:UP000001593};
RN [1] {ECO:0000313|EMBL:EDO46664.1, ECO:0000313|Proteomes:UP000001593}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CH2 X CH6 {ECO:0000313|Proteomes:UP000001593};
RX PubMed=17615350; DOI=10.1126/science.1139158;
RA Putnam N.H., Srivastava M., Hellsten U., Dirks B., Chapman J., Salamov A.,
RA Terry A., Shapiro H., Lindquist E., Kapitonov V.V., Jurka J.,
RA Genikhovich G., Grigoriev I.V., Lucas S.M., Steele R.E., Finnerty J.R.,
RA Technau U., Martindale M.Q., Rokhsar D.S.;
RT "Sea anemone genome reveals ancestral eumetazoan gene repertoire and
RT genomic organization.";
RL Science 317:86-94(2007).
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123,
CC ECO:0000256|PROSITE-ProRule:PRU00201}.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00201}.
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DR EMBL; DS469525; EDO46664.1; -; Genomic_DNA.
DR RefSeq; XP_001638727.1; XM_001638677.1.
DR AlphaFoldDB; A7RPC8; -.
DR EnsemblMetazoa; EDO46664; EDO46664; NEMVEDRAFT_v1g88753.
DR KEGG; nve:5518797; -.
DR eggNOG; KOG3586; Eukaryota.
DR HOGENOM; CLU_014430_3_1_1; -.
DR InParanoid; A7RPC8; -.
DR OMA; HEMSSRY; -.
DR OrthoDB; 2914470at2759; -.
DR PhylomeDB; A7RPC8; -.
DR Proteomes; UP000001593; Unassembled WGS sequence.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR GO; GO:0000978; F:RNA polymerase II cis-regulatory region sequence-specific DNA binding; IEA:InterPro.
DR GO; GO:0045893; P:positive regulation of DNA-templated transcription; IEA:InterPro.
DR CDD; cd20191; T-box_TBX15_18_22-like; 1.
DR Gene3D; 2.60.40.820; Transcription factor, T-box; 1.
DR InterPro; IPR008967; p53-like_TF_DNA-bd_sf.
DR InterPro; IPR046360; T-box_DNA-bd.
DR InterPro; IPR036960; T-box_sf.
DR InterPro; IPR001699; TF_T-box.
DR InterPro; IPR018186; TF_T-box_CS.
DR PANTHER; PTHR11267:SF129; LP04777P-RELATED; 1.
DR PANTHER; PTHR11267; T-BOX PROTEIN-RELATED; 1.
DR Pfam; PF00907; T-box; 1.
DR PRINTS; PR00937; TBOX.
DR SMART; SM00425; TBOX; 1.
DR SUPFAM; SSF49417; p53-like transcription factors; 1.
DR PROSITE; PS01283; TBOX_1; 1.
DR PROSITE; PS01264; TBOX_2; 1.
DR PROSITE; PS50252; TBOX_3; 1.
PE 4: Predicted;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125, ECO:0000256|PROSITE-
KW ProRule:PRU00201};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242, ECO:0000256|PROSITE-
KW ProRule:PRU00201}; Reference proteome {ECO:0000313|Proteomes:UP000001593};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT DOMAIN 5..191
FT /note="T-box"
FT /evidence="ECO:0000259|PROSITE:PS50252"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:EDO46664.1"
FT NON_TER 195
FT /evidence="ECO:0000313|EMBL:EDO46664.1"
SQ SEQUENCE 195 AA; 22730 MW; 6FA1A330A5530996 CRC64;
IRVELQMHDL WRRFYELGTE MIITKAGRRM FPAIRVKVSG LDLHAHYILV MDVIPLDGKR
YRYAYHSSKW VVAGNADAPM PGRVYIHPDS PALGEEWMRQ IVSFDKVKLT NNELDQQGHI
ILHSMHKYQP RIHIIRKKDT SEASIDIDRP CSERKTFTFS ETVFTTVTAY QNQQITRLKI
DSNPFAKGFR DSGRL
//
