ID   A7RQH5_NEMVE            Unreviewed;       463 AA.
AC   A7RQH5;
DT   02-OCT-2007, integrated into UniProtKB/TrEMBL.
DT   02-OCT-2007, sequence version 1.
DT   27-MAR-2024, entry version 80.
DE   RecName: Full=Adenylyl cyclase-associated protein {ECO:0000256|RuleBase:RU000647};
GN   ORFNames=NEMVEDRAFT_v1g161560 {ECO:0000313|EMBL:EDO46368.1};
OS   Nematostella vectensis (Starlet sea anemone).
OC   Eukaryota; Metazoa; Cnidaria; Anthozoa; Hexacorallia; Actiniaria;
OC   Edwardsiidae; Nematostella.
OX   NCBI_TaxID=45351 {ECO:0000313|EMBL:EDO46368.1, ECO:0000313|Proteomes:UP000001593};
RN   [1] {ECO:0000313|EMBL:EDO46368.1, ECO:0000313|Proteomes:UP000001593}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CH2 X CH6 {ECO:0000313|Proteomes:UP000001593};
RX   PubMed=17615350; DOI=10.1126/science.1139158;
RA   Putnam N.H., Srivastava M., Hellsten U., Dirks B., Chapman J., Salamov A.,
RA   Terry A., Shapiro H., Lindquist E., Kapitonov V.V., Jurka J.,
RA   Genikhovich G., Grigoriev I.V., Lucas S.M., Steele R.E., Finnerty J.R.,
RA   Technau U., Martindale M.Q., Rokhsar D.S.;
RT   "Sea anemone genome reveals ancestral eumetazoan gene repertoire and
RT   genomic organization.";
RL   Science 317:86-94(2007).
CC   -!- SIMILARITY: Belongs to the CAP family. {ECO:0000256|ARBA:ARBA00007659,
CC       ECO:0000256|RuleBase:RU000647}.
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DR   EMBL; DS469528; EDO46368.1; -; Genomic_DNA.
DR   RefSeq; XP_001638431.1; XM_001638381.1.
DR   AlphaFoldDB; A7RQH5; -.
DR   STRING; 45351.A7RQH5; -.
DR   EnsemblMetazoa; EDO46368; EDO46368; NEMVEDRAFT_v1g161560.
DR   GeneID; 5518401; -.
DR   KEGG; nve:5518401; -.
DR   eggNOG; KOG2675; Eukaryota.
DR   HOGENOM; CLU_015780_1_0_1; -.
DR   InParanoid; A7RQH5; -.
DR   OMA; KSQQTHK; -.
DR   OrthoDB; 1453907at2759; -.
DR   PhylomeDB; A7RQH5; -.
DR   Proteomes; UP000001593; Unassembled WGS sequence.
DR   GO; GO:0005737; C:cytoplasm; IBA:GO_Central.
DR   GO; GO:0003779; F:actin binding; IBA:GO_Central.
DR   GO; GO:0008179; F:adenylate cyclase binding; IBA:GO_Central.
DR   GO; GO:0007015; P:actin filament organization; IBA:GO_Central.
DR   GO; GO:0019933; P:cAMP-mediated signaling; IBA:GO_Central.
DR   GO; GO:0000902; P:cell morphogenesis; IBA:GO_Central.
DR   Gene3D; 2.160.20.70; -; 1.
DR   Gene3D; 1.25.40.330; Adenylate cyclase-associated CAP, N-terminal domain; 1.
DR   InterPro; IPR001837; Adenylate_cyclase-assoc_CAP.
DR   InterPro; IPR013912; Adenylate_cyclase-assoc_CAP_C.
DR   InterPro; IPR013992; Adenylate_cyclase-assoc_CAP_N.
DR   InterPro; IPR017901; C-CAP_CF_C-like.
DR   InterPro; IPR016098; CAP/MinC_C.
DR   InterPro; IPR036223; CAP_C_sf.
DR   InterPro; IPR028417; CAP_CS_C.
DR   InterPro; IPR018106; CAP_CS_N.
DR   InterPro; IPR036222; CAP_N_sf.
DR   InterPro; IPR006599; CARP_motif.
DR   PANTHER; PTHR10652; ADENYLYL CYCLASE-ASSOCIATED PROTEIN; 1.
DR   PANTHER; PTHR10652:SF0; ADENYLYL CYCLASE-ASSOCIATED PROTEIN; 1.
DR   Pfam; PF08603; CAP_C; 1.
DR   Pfam; PF01213; CAP_N; 1.
DR   SMART; SM00673; CARP; 2.
DR   SUPFAM; SSF69340; C-terminal domain of adenylylcyclase associated protein; 1.
DR   SUPFAM; SSF101278; N-terminal domain of adenylylcyclase associated protein, CAP; 1.
DR   PROSITE; PS51329; C_CAP_COFACTOR_C; 1.
DR   PROSITE; PS01088; CAP_1; 1.
DR   PROSITE; PS01089; CAP_2; 1.
PE   3: Inferred from homology;
KW   Reference proteome {ECO:0000313|Proteomes:UP000001593}.
FT   DOMAIN          308..441
FT                   /note="C-CAP/cofactor C-like"
FT                   /evidence="ECO:0000259|PROSITE:PS51329"
FT   REGION          201..245
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        211..239
FT                   /note="Pro residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   463 AA;  49934 MW;  DC8E45D417ED26C5 CRC64;
     MAGNLDPLVV RLEAVTSRLE AMASKSGSGG SGGTEANEEI VSFYDKFLSE SVAKCLKISS
     EIGGDVGSQA KLVDQAFKAQ RDFLVLVSKH QCPSANVLQT LLTKTSQAIS AVQEFREKNR
     RSNYFNHLSS WSEGIPALGW VTVVKGANFV NEMNGSAEFY LNRVLKDFKE KDAKHVEWVK
     SVKAIFVALK EYINEFHKSG LTWNQSGPPA PTSVPSGPRA PPGGPGAPPP PPPPAVVPPS
     AVTTDGKPAT AALFSEINKA GTNIASGLRK VTDDQKTHKN PNLRASSVVK DKPKPTIAKK
     PVAVTKKPPV FELQGKKWMV EHQEGNKNLT IEGSMSQVVY IYSCKDSVVI IKGKINSITL
     DNCKKCAVVF DDAIATVEFV NCQSVQCQVN GKVPTVSIDK TDGCQVYLSK DSLQSEIVTA
     KSSEMNILVQ QADGDYVENP LPEQYKSVWD GKAFVTTPVA SHG
//