ID A7RVR6_NEMVE Unreviewed; 814 AA.
AC A7RVR6;
DT 02-OCT-2007, integrated into UniProtKB/TrEMBL.
DT 02-OCT-2007, sequence version 1.
DT 27-MAR-2024, entry version 77.
DE RecName: Full=Transcriptional regulator ATRX homolog {ECO:0008006|Google:ProtNLM};
GN ORFNames=NEMVEDRAFT_v1g94894 {ECO:0000313|EMBL:EDO44496.1};
OS Nematostella vectensis (Starlet sea anemone).
OC Eukaryota; Metazoa; Cnidaria; Anthozoa; Hexacorallia; Actiniaria;
OC Edwardsiidae; Nematostella.
OX NCBI_TaxID=45351 {ECO:0000313|EMBL:EDO44496.1, ECO:0000313|Proteomes:UP000001593};
RN [1] {ECO:0000313|EMBL:EDO44496.1, ECO:0000313|Proteomes:UP000001593}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CH2 X CH6 {ECO:0000313|Proteomes:UP000001593};
RX PubMed=17615350; DOI=10.1126/science.1139158;
RA Putnam N.H., Srivastava M., Hellsten U., Dirks B., Chapman J., Salamov A.,
RA Terry A., Shapiro H., Lindquist E., Kapitonov V.V., Jurka J.,
RA Genikhovich G., Grigoriev I.V., Lucas S.M., Steele R.E., Finnerty J.R.,
RA Technau U., Martindale M.Q., Rokhsar D.S.;
RT "Sea anemone genome reveals ancestral eumetazoan gene repertoire and
RT genomic organization.";
RL Science 317:86-94(2007).
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
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DR EMBL; DS469544; EDO44496.1; -; Genomic_DNA.
DR RefSeq; XP_001636559.1; XM_001636509.1.
DR AlphaFoldDB; A7RVR6; -.
DR STRING; 45351.A7RVR6; -.
DR EnsemblMetazoa; EDO44496; EDO44496; NEMVEDRAFT_v1g94894.
DR eggNOG; KOG1015; Eukaryota.
DR HOGENOM; CLU_000315_11_3_1; -.
DR InParanoid; A7RVR6; -.
DR OMA; MELYTYE; -.
DR PhylomeDB; A7RVR6; -.
DR Proteomes; UP000001593; Unassembled WGS sequence.
DR GO; GO:0005634; C:nucleus; IBA:GO_Central.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0140658; F:ATP-dependent chromatin remodeler activity; IEA:InterPro.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0004386; F:helicase activity; IEA:UniProtKB-KW.
DR CDD; cd18793; SF2_C_SNF; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 3.40.50.10810; Tandem AAA-ATPase domain; 1.
DR InterPro; IPR044574; ARIP4-like.
DR InterPro; IPR014001; Helicase_ATP-bd.
DR InterPro; IPR001650; Helicase_C.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR038718; SNF2-like_sf.
DR InterPro; IPR049730; SNF2/RAD54-like_C.
DR InterPro; IPR000330; SNF2_N.
DR PANTHER; PTHR45797; RAD54-LIKE; 1.
DR PANTHER; PTHR45797:SF3; RAD54-LIKE; 1.
DR Pfam; PF00271; Helicase_C; 1.
DR Pfam; PF00176; SNF2-rel_dom; 1.
DR SMART; SM00487; DEXDc; 1.
DR SMART; SM00490; HELICc; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 2.
DR PROSITE; PS51192; HELICASE_ATP_BIND_1; 1.
DR PROSITE; PS51194; HELICASE_CTER; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000001593}.
FT DOMAIN 128..318
FT /note="Helicase ATP-binding"
FT /evidence="ECO:0000259|PROSITE:PS51192"
FT DOMAIN 558..718
FT /note="Helicase C-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51194"
FT REGION 1..52
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 462..525
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 23..52
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 475..506
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 507..521
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 814 AA; 93376 MW; 4E98429027575F0A CRC64;
MAKGKRKRVK EMSESEDENE EEPDTPSKSK GRRKIRKLLT DEKLGEETKK ARRLEEERRQ
RLLERTQNLS EDMPSMDWKV DSLVLESDPE TKEPIVEVNK HIVKYLKPHQ CKGVQFMYDC
LVESVKAYKK GEPGSGCILA HCMGLGKTLQ VVTLVHTLFN NKELEFTTAL VVAPLNTLLN
WQVEFEKWLS HLSKPPFPIF QVYVLQEVGH NSWRRADMLT QWQRYGGIMI MGYDMYRNLS
LCNNVRSKKV KKIFKETLVD PGPDIVICDE GHILKNDASA ISRALNAIKT RRRVVLTGTP
LQNNLIEYHC MVSFVKPSLL GTRKEFMNTF GNPIQNGQCA DSTPSDFRIM KQRCHVLFKM
LEGCVQRRDY SVLTPFLPAK HEYVIKVRLS EAQRKLYEHY LKTFVFPEGD VTKRGVGLFS
DYQALMRIWT HPWCLKLEAI RRSMRMTYDD SDDSLDGFVV HTDEESESTA ESESEEDTDA
NKGRGKSRRK DSGDEVIPEK RASGTARKTR NSLQTTRSSK PSKVEIDGED VVEVDAKPGP
SEAEYNVELS GKLVLLLEIL ADAEAVEEKV LVFSQSLVSL DLIERALGGG EVGGDRENWC
KGCDYFRMDG STSVQLRQRW ADIFNDPDNK TARLFLISTK AGGLGINLVA ANRVIVFDAS
WNPSHDVQSI FRVYRFGQTK AVYVYRFLSQ GTMEERVYDR QVAKLSISER VVDKHQIERH
FTAADLAELY KFDPDVLDET KNKEDIPSLP LPKDAILADL INRMHPQWIV KYHEHDSLLR
NIEEEELTEE EMKIAWKAYQ DEKEAANNPA CKLR
//
