ID A7RXX8_NEMVE Unreviewed; 384 AA.
AC A7RXX8;
DT 02-OCT-2007, integrated into UniProtKB/TrEMBL.
DT 02-OCT-2007, sequence version 1.
DT 27-MAR-2024, entry version 56.
DE RecName: Full=G-protein coupled receptors family 1 profile domain-containing protein {ECO:0000259|PROSITE:PS50262};
GN ORFNames=NEMVEDRAFT_v1g203786 {ECO:0000313|EMBL:EDO43740.1};
OS Nematostella vectensis (Starlet sea anemone).
OC Eukaryota; Metazoa; Cnidaria; Anthozoa; Hexacorallia; Actiniaria;
OC Edwardsiidae; Nematostella.
OX NCBI_TaxID=45351 {ECO:0000313|EMBL:EDO43740.1, ECO:0000313|Proteomes:UP000001593};
RN [1] {ECO:0000313|EMBL:EDO43740.1, ECO:0000313|Proteomes:UP000001593}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CH2 X CH6 {ECO:0000313|Proteomes:UP000001593};
RX PubMed=17615350; DOI=10.1126/science.1139158;
RA Putnam N.H., Srivastava M., Hellsten U., Dirks B., Chapman J., Salamov A.,
RA Terry A., Shapiro H., Lindquist E., Kapitonov V.V., Jurka J.,
RA Genikhovich G., Grigoriev I.V., Lucas S.M., Steele R.E., Finnerty J.R.,
RA Technau U., Martindale M.Q., Rokhsar D.S.;
RT "Sea anemone genome reveals ancestral eumetazoan gene repertoire and
RT genomic organization.";
RL Science 317:86-94(2007).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR EMBL; DS469551; EDO43740.1; -; Genomic_DNA.
DR RefSeq; XP_001635803.1; XM_001635753.1.
DR AlphaFoldDB; A7RXX8; -.
DR STRING; 45351.A7RXX8; -.
DR EnsemblMetazoa; EDO43740; EDO43740; NEMVEDRAFT_v1g203786.
DR GeneID; 5515686; -.
DR KEGG; nve:5515686; -.
DR eggNOG; KOG3656; Eukaryota.
DR HOGENOM; CLU_009579_14_1_1; -.
DR InParanoid; A7RXX8; -.
DR OMA; LWREENT; -.
DR OrthoDB; 4632625at2759; -.
DR PhylomeDB; A7RXX8; -.
DR Proteomes; UP000001593; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0004930; F:G protein-coupled receptor activity; IEA:InterPro.
DR CDD; cd00637; 7tm_classA_rhodopsin-like; 1.
DR Gene3D; 1.20.1070.10; Rhodopsin 7-helix transmembrane proteins; 1.
DR InterPro; IPR000276; GPCR_Rhodpsn.
DR InterPro; IPR017452; GPCR_Rhodpsn_7TM.
DR PANTHER; PTHR24246:SF27; ADENOSINE RECEPTOR, ISOFORM A; 1.
DR PANTHER; PTHR24246; OLFACTORY RECEPTOR AND ADENOSINE RECEPTOR; 1.
DR Pfam; PF00001; 7tm_1; 1.
DR PRINTS; PR00237; GPCRRHODOPSN.
DR SMART; SM01381; 7TM_GPCR_Srsx; 1.
DR SUPFAM; SSF81321; Family A G protein-coupled receptor-like; 1.
DR PROSITE; PS50262; G_PROTEIN_RECEP_F1_2; 1.
PE 4: Predicted;
KW G-protein coupled receptor {ECO:0000256|ARBA:ARBA00023040};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Receptor {ECO:0000256|ARBA:ARBA00023170};
KW Reference proteome {ECO:0000313|Proteomes:UP000001593};
KW Transducer {ECO:0000256|ARBA:ARBA00023224};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 36..57
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 69..94
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 106..129
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 149..167
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 179..200
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 303..328
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 340..362
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 48..360
FT /note="G-protein coupled receptors family 1 profile"
FT /evidence="ECO:0000259|PROSITE:PS50262"
SQ SEQUENCE 384 AA; 42778 MW; 23AB15D9016C6BF1 CRC64;
MNNSWVDFTK CAYWSHHTIT PANYASLFAL DCALSVINGL TSPATFASNA LILFAILKTP
LLHTPTNVLV FSLVLADSLV GILLQPLAVV YLLIEGNTCT VIDALTFLNV TVIGVSLSTM
ALVSLDLYLS LYFPFRYPSK VTIRRVSSVS IIVWLYWTIM VAIPMVTPGR TAMLLVESVL
GVTWLVCLVV IAISYFRIFW LVRYHVTKIK TLTPVEHTGP QPIGDREANV NHRGSLNLQF
LSKVKEKEDF PVSDQKLSVI NSKPISTCSQ AVSCQQSAKD QPNITRPKPI TAQQPVRARK
TKLAVTMGYV IGTSLFCYFP FGVVVLFLRA NPNPSLSLVA AFYVLITLQF LSSFVNPLVY
CWRVRELREA CSTLLRSLGR RFFN
//
