ID A7S048_NEMVE Unreviewed; 593 AA.
AC A7S048;
DT 02-OCT-2007, integrated into UniProtKB/TrEMBL.
DT 02-OCT-2007, sequence version 1.
DT 24-JAN-2024, entry version 67.
DE RecName: Full=ACB domain-containing protein {ECO:0000259|PROSITE:PS51228};
GN ORFNames=NEMVEDRAFT_v1g241917 {ECO:0000313|EMBL:EDO42901.1};
OS Nematostella vectensis (Starlet sea anemone).
OC Eukaryota; Metazoa; Cnidaria; Anthozoa; Hexacorallia; Actiniaria;
OC Edwardsiidae; Nematostella.
OX NCBI_TaxID=45351 {ECO:0000313|EMBL:EDO42901.1, ECO:0000313|Proteomes:UP000001593};
RN [1] {ECO:0000313|EMBL:EDO42901.1, ECO:0000313|Proteomes:UP000001593}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CH2 X CH6 {ECO:0000313|Proteomes:UP000001593};
RX PubMed=17615350; DOI=10.1126/science.1139158;
RA Putnam N.H., Srivastava M., Hellsten U., Dirks B., Chapman J., Salamov A.,
RA Terry A., Shapiro H., Lindquist E., Kapitonov V.V., Jurka J.,
RA Genikhovich G., Grigoriev I.V., Lucas S.M., Steele R.E., Finnerty J.R.,
RA Technau U., Martindale M.Q., Rokhsar D.S.;
RT "Sea anemone genome reveals ancestral eumetazoan gene repertoire and
RT genomic organization.";
RL Science 317:86-94(2007).
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DR EMBL; DS469559; EDO42901.1; -; Genomic_DNA.
DR RefSeq; XP_001634964.1; XM_001634914.1.
DR AlphaFoldDB; A7S048; -.
DR STRING; 45351.A7S048; -.
DR EnsemblMetazoa; EDO42901; EDO42901; NEMVEDRAFT_v1g241917.
DR GeneID; 5514849; -.
DR KEGG; nve:5514849; -.
DR eggNOG; KOG0817; Eukaryota.
DR HOGENOM; CLU_460275_0_0_1; -.
DR InParanoid; A7S048; -.
DR OMA; HENSFHE; -.
DR OrthoDB; 5402066at2759; -.
DR Proteomes; UP000001593; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IBA:GO_Central.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0000062; F:fatty-acyl-CoA binding; IBA:GO_Central.
DR GO; GO:0006631; P:fatty acid metabolic process; IBA:GO_Central.
DR Gene3D; 1.20.80.10; -; 1.
DR InterPro; IPR000582; Acyl-CoA-binding_protein.
DR InterPro; IPR035984; Acyl-CoA-binding_sf.
DR InterPro; IPR014352; FERM/acyl-CoA-bd_prot_sf.
DR PANTHER; PTHR23310; ACYL-COA-BINDING PROTEIN, ACBP; 1.
DR PANTHER; PTHR23310:SF77; LD25952P; 1.
DR Pfam; PF00887; ACBP; 1.
DR PRINTS; PR00689; ACOABINDINGP.
DR SUPFAM; SSF47027; Acyl-CoA binding protein; 1.
DR PROSITE; PS51228; ACB_2; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Lipid-binding {ECO:0000256|ARBA:ARBA00023121};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000001593};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 566..584
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 5..94
FT /note="ACB"
FT /evidence="ECO:0000259|PROSITE:PS51228"
FT REGION 250..279
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 428..511
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 514..541
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 254..272
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 437..470
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 485..511
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 593 AA; 66542 MW; B54D2D4C53F75A0B CRC64;
MADSAERRFE AAINVVKSMP KKGAYQPSYD TMLKFYGYFK QAKEGECRDT KPGFWDVIKK
AKWEAWSALG DLPKQDAMEC YVNEVKKVME EIPENEEMAD FSLVLKEFYE TVYEPVGEDP
PPMLRIFKKD DTLINSGDFT ANSINDQEQG NMEGDESIPN GLQLISDKHS NEQHLISGLV
NGNRDKLSNV DGISVPMKAI GTNHEYTTTD TSDRGALNEV ETSDGADCQI VPATDISVEE
PQPLYIFEIG SKGRPTESND SGFQSDQHGR EIATNETVPE LKPQRSDVAL YDYQGVITSD
ESDEEFCDSL DPEHLSNLQN GHSDVGVTNI TEIKELDSSN GSSALSSNSP LTDSEVSRFD
IPVTATASLL TSTPFTTKHA AHVTFADQVG FNEDNLTEKE MRRNGYPVTR QDLKNNGNVV
HNVNGMLKAT GGIPKQRGGG TSPSRQFDKQ ADNQQQQQQQ QQQGQQSKAV RNPGAVVKGG
KPNLQRLKDY SDSDSDDDEK NESMTSSVDR DEINERILAA LEGLQRDMQH VLRQLQDMEH
RTSNTNDTSL INRAQQWWKQ YIPSKTVLFL VLWPFVINIL FHYYRKRRIL KKT
//
