ID A7S591_NEMVE Unreviewed; 249 AA.
AC A7S591;
DT 02-OCT-2007, integrated into UniProtKB/TrEMBL.
DT 02-OCT-2007, sequence version 1.
DT 24-JAN-2024, entry version 68.
DE RecName: Full=Fe2OG dioxygenase domain-containing protein {ECO:0000259|PROSITE:PS51471};
GN ORFNames=NEMVEDRAFT_v1g105050 {ECO:0000313|EMBL:EDO41203.1};
OS Nematostella vectensis (Starlet sea anemone).
OC Eukaryota; Metazoa; Cnidaria; Anthozoa; Hexacorallia; Actiniaria;
OC Edwardsiidae; Nematostella.
OX NCBI_TaxID=45351 {ECO:0000313|EMBL:EDO41203.1, ECO:0000313|Proteomes:UP000001593};
RN [1] {ECO:0000313|EMBL:EDO41203.1, ECO:0000313|Proteomes:UP000001593}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CH2 X CH6 {ECO:0000313|Proteomes:UP000001593};
RX PubMed=17615350; DOI=10.1126/science.1139158;
RA Putnam N.H., Srivastava M., Hellsten U., Dirks B., Chapman J., Salamov A.,
RA Terry A., Shapiro H., Lindquist E., Kapitonov V.V., Jurka J.,
RA Genikhovich G., Grigoriev I.V., Lucas S.M., Steele R.E., Finnerty J.R.,
RA Technau U., Martindale M.Q., Rokhsar D.S.;
RT "Sea anemone genome reveals ancestral eumetazoan gene repertoire and
RT genomic organization.";
RL Science 317:86-94(2007).
CC -!- COFACTOR:
CC Name=L-ascorbate; Xref=ChEBI:CHEBI:38290;
CC Evidence={ECO:0000256|ARBA:ARBA00001961};
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DR EMBL; DS469581; EDO41203.1; -; Genomic_DNA.
DR RefSeq; XP_001633266.1; XM_001633216.1.
DR AlphaFoldDB; A7S591; -.
DR STRING; 45351.A7S591; -.
DR EnsemblMetazoa; EDO41203; EDO41203; NEMVEDRAFT_v1g105050.
DR eggNOG; ENOG502QR2P; Eukaryota.
DR HOGENOM; CLU_042482_0_0_1; -.
DR InParanoid; A7S591; -.
DR OMA; YESFHYT; -.
DR PhylomeDB; A7S591; -.
DR Proteomes; UP000001593; Unassembled WGS sequence.
DR GO; GO:0051213; F:dioxygenase activity; IEA:UniProtKB-KW.
DR GO; GO:0005506; F:iron ion binding; IEA:InterPro.
DR GO; GO:0031418; F:L-ascorbic acid binding; IEA:InterPro.
DR GO; GO:0016705; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; IEA:InterPro.
DR Gene3D; 2.60.120.620; q2cbj1_9rhob like domain; 1.
DR InterPro; IPR039210; OGFOD3.
DR InterPro; IPR005123; Oxoglu/Fe-dep_dioxygenase.
DR InterPro; IPR006620; Pro_4_hyd_alph.
DR InterPro; IPR044862; Pro_4_hyd_alph_FE2OG_OXY.
DR PANTHER; PTHR14650:SF1; 2-OXOGLUTARATE AND IRON-DEPENDENT OXYGENASE DOMAIN-CONTAINING PROTEIN 3; 1.
DR PANTHER; PTHR14650; PROLYL HYDROXYLASE-RELATED; 1.
DR Pfam; PF13640; 2OG-FeII_Oxy_3; 1.
DR SMART; SM00702; P4Hc; 1.
DR PROSITE; PS51471; FE2OG_OXY; 1.
PE 4: Predicted;
KW Dioxygenase {ECO:0000256|ARBA:ARBA00022964};
KW Iron {ECO:0000256|ARBA:ARBA00023004};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW Reference proteome {ECO:0000313|Proteomes:UP000001593}.
FT DOMAIN 138..237
FT /note="Fe2OG dioxygenase"
FT /evidence="ECO:0000259|PROSITE:PS51471"
SQ SEQUENCE 249 AA; 28051 MW; 2F8F911D7A18D2E3 CRC64;
MITFVSVDDS VSRKFLNVKC SNDYGTKFKS CVPKKCGRAV MDDVVSFEEA VYLADLAKRG
MKHGGSSGGP TILDLHSGAL TYGEKFVNIY TLAKKLKTGE LFTKKDFEVY KQVKNKIKNA
IATEFNIDQN SLYLTKPTFF SRMTAKPAKT IHDEYWHPHI DKTTYGSFYY TSLLYLSDYG
RNFTGGRFVF VDKNTNHTVE PKTARVSFFT SGSENLHHVE KVKNGTRFAI TVSFTCDPKF
AITDPSAEP
//
