ID A7SBW5_NEMVE Unreviewed; 474 AA.
AC A7SBW5;
DT 02-OCT-2007, integrated into UniProtKB/TrEMBL.
DT 02-OCT-2007, sequence version 1.
DT 27-MAR-2024, entry version 65.
DE RecName: Full=Major facilitator superfamily (MFS) profile domain-containing protein {ECO:0000259|PROSITE:PS50850};
GN ORFNames=NEMVEDRAFT_v1g244203 {ECO:0000313|EMBL:EDO38796.1};
OS Nematostella vectensis (Starlet sea anemone).
OC Eukaryota; Metazoa; Cnidaria; Anthozoa; Hexacorallia; Actiniaria;
OC Edwardsiidae; Nematostella.
OX NCBI_TaxID=45351 {ECO:0000313|EMBL:EDO38796.1, ECO:0000313|Proteomes:UP000001593};
RN [1] {ECO:0000313|EMBL:EDO38796.1, ECO:0000313|Proteomes:UP000001593}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CH2 X CH6 {ECO:0000313|Proteomes:UP000001593};
RX PubMed=17615350; DOI=10.1126/science.1139158;
RA Putnam N.H., Srivastava M., Hellsten U., Dirks B., Chapman J., Salamov A.,
RA Terry A., Shapiro H., Lindquist E., Kapitonov V.V., Jurka J.,
RA Genikhovich G., Grigoriev I.V., Lucas S.M., Steele R.E., Finnerty J.R.,
RA Technau U., Martindale M.Q., Rokhsar D.S.;
RT "Sea anemone genome reveals ancestral eumetazoan gene repertoire and
RT genomic organization.";
RL Science 317:86-94(2007).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the major facilitator superfamily. MFSD6 family.
CC {ECO:0000256|ARBA:ARBA00005241}.
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DR EMBL; DS469619; EDO38796.1; -; Genomic_DNA.
DR RefSeq; XP_001630859.1; XM_001630809.1.
DR AlphaFoldDB; A7SBW5; -.
DR TCDB; 2.A.1.65.4; the major facilitator superfamily (mfs).
DR EnsemblMetazoa; EDO38796; EDO38796; NEMVEDRAFT_v1g244203.
DR GeneID; 5510389; -.
DR KEGG; nve:5510389; -.
DR eggNOG; KOG3762; Eukaryota.
DR HOGENOM; CLU_013133_2_1_1; -.
DR InParanoid; A7SBW5; -.
DR OMA; ENIYCDI; -.
DR OrthoDB; 1365658at2759; -.
DR PhylomeDB; A7SBW5; -.
DR Proteomes; UP000001593; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IBA:GO_Central.
DR GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
DR CDD; cd17335; MFS_MFSD6; 1.
DR Gene3D; 1.20.1250.20; MFS general substrate transporter like domains; 2.
DR InterPro; IPR024989; MFS_assoc_dom.
DR InterPro; IPR020846; MFS_dom.
DR InterPro; IPR036259; MFS_trans_sf.
DR PANTHER; PTHR16172:SF41; MFS_1_LIKE DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR16172; UNCHARACTERIZED; 1.
DR Pfam; PF12832; MFS_1_like; 1.
DR SUPFAM; SSF103473; MFS general substrate transporter; 1.
DR PROSITE; PS50850; MFS; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000001593};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 20..38
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 82..103
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 181..198
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 218..244
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 265..289
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 295..316
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 328..348
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 360..382
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 394..415
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 421..441
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 264..474
FT /note="Major facilitator superfamily (MFS) profile"
FT /evidence="ECO:0000259|PROSITE:PS50850"
SQ SEQUENCE 474 AA; 51638 MW; 9B10C5236F272494 CRC64;
MSIRSNIREF FSIDASTVKY KIFFVLHFFG LGSIPLYLPV FLRSIGIDAF HSGIITALRK
LVRIPSSPLI GAIADKSLRH KLTLMVCVVL GTCLYSGLSY IPIVQGMERN GYNLSEDEGS
QAIATETVHL SIHGRLSTQV IFATALFFVV SGEFFNDPLE SILAASIVNQ VGVERYGHQR
LYGAFGFGIG SLVTGFAMDQ TSHVTYIPGS LPHHGPNFLT AFIINFGLSV FALLLIGFTF
EITINEKKIP PNFAKHIGLL IRKETVLFLI ILFITGVANG VIMSFLFWFL RDIGASQTLL
GLVTVVMCSA EMLVFSCTGT MIGRLGHVGV IILALACTII RLLIYPFLEN PWYVLLVEPM
NGITFAAMWA TCVSYASILA PNEVQSTMQG VVSSVYYNLG GGTGSLLGGM VYKAYGPRSM
FWATAGLCGV GMPLAIALYC INSVKEKISN GYDLVNEDEN LELPLALNDA NIAR
//
