ID A7SC28_NEMVE Unreviewed; 587 AA.
AC A7SC28;
DT 02-OCT-2007, integrated into UniProtKB/TrEMBL.
DT 02-OCT-2007, sequence version 1.
DT 27-MAR-2024, entry version 81.
DE RecName: Full=RRM domain-containing protein {ECO:0000259|PROSITE:PS50102};
GN ORFNames=NEMVEDRAFT_v1g209974 {ECO:0000313|EMBL:EDO38763.1};
OS Nematostella vectensis (Starlet sea anemone).
OC Eukaryota; Metazoa; Cnidaria; Anthozoa; Hexacorallia; Actiniaria;
OC Edwardsiidae; Nematostella.
OX NCBI_TaxID=45351 {ECO:0000313|EMBL:EDO38763.1, ECO:0000313|Proteomes:UP000001593};
RN [1] {ECO:0000313|EMBL:EDO38763.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CH2 x CH6 {ECO:0000313|EMBL:EDO38763.1};
RX PubMed=17615350; DOI=10.1126/science.1139158;
RA Putnam N.H., Srivastava M., Hellsten U., Dirks B., Chapman J., Salamov A.,
RA Terry A., Shapiro H., Lindquist E., Kapitonov V.V., Jurka J.,
RA Genikhovich G., Grigoriev I.V., Lucas S.M., Steele R.E., Finnerty J.R.,
RA Technau U., Martindale M.Q., Rokhsar D.S.;
RT "Sea anemone genome reveals ancestral eumetazoan gene repertoire and
RT genomic organization.";
RL Science 317:86-94(2007).
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
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DR EMBL; DS469620; EDO38763.1; -; Genomic_DNA.
DR RefSeq; XP_001630826.1; XM_001630776.1.
DR AlphaFoldDB; A7SC28; -.
DR STRING; 45351.A7SC28; -.
DR EnsemblMetazoa; EDO38763; EDO38763; NEMVEDRAFT_v1g209974.
DR eggNOG; KOG0117; Eukaryota.
DR HOGENOM; CLU_022960_2_1_1; -.
DR InParanoid; A7SC28; -.
DR OMA; GRANNMY; -.
DR PhylomeDB; A7SC28; -.
DR Proteomes; UP000001593; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0005634; C:nucleus; IBA:GO_Central.
DR GO; GO:1990904; C:ribonucleoprotein complex; IBA:GO_Central.
DR GO; GO:0003729; F:mRNA binding; IBA:GO_Central.
DR CDD; cd12249; RRM1_hnRNPR_like; 1.
DR CDD; cd12250; RRM2_hnRNPR_like; 1.
DR CDD; cd12251; RRM3_hnRNPR_like; 1.
DR Gene3D; 3.30.70.330; -; 3.
DR InterPro; IPR041337; hnRNP_Q_AcD.
DR InterPro; IPR006535; HnRNP_R/Q_splicing_fac.
DR InterPro; IPR012677; Nucleotide-bd_a/b_plait_sf.
DR InterPro; IPR035979; RBD_domain_sf.
DR InterPro; IPR000504; RRM_dom.
DR NCBIfam; TIGR01648; hnRNP-R-Q; 1.
DR PANTHER; PTHR21245; HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN; 1.
DR PANTHER; PTHR21245:SF10; SYNCRIP, ISOFORM Q; 1.
DR Pfam; PF18360; hnRNP_Q_AcD; 1.
DR Pfam; PF00076; RRM_1; 3.
DR SMART; SM00360; RRM; 3.
DR SUPFAM; SSF54928; RNA-binding domain, RBD; 2.
DR PROSITE; PS50102; RRM; 3.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000001593};
KW RNA-binding {ECO:0000256|PROSITE-ProRule:PRU00176}.
FT DOMAIN 152..231
FT /note="RRM"
FT /evidence="ECO:0000259|PROSITE:PS50102"
FT DOMAIN 233..316
FT /note="RRM"
FT /evidence="ECO:0000259|PROSITE:PS50102"
FT DOMAIN 329..399
FT /note="RRM"
FT /evidence="ECO:0000259|PROSITE:PS50102"
FT REGION 125..145
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 394..432
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 470..587
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 553..587
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 587 AA; 64222 MW; F15635BC44BE12A0 CRC64;
MAQETPLTEE AKQLVNIGVS LKVAQRVGEI FSSGSLAPEE LDDRALDALR EFNEEGALEV
LNQFASSDLS HVQNKSAFLC GVMKTYREKN RMRRDGQDPT AGLKGPDEAK IKALLDRTGY
TLDITTGQRK YGGPPPGWEG KPPGTGSEKV CSQVFIGKVP RDCFEDELIP VFEECGHIYD
FRLMIDPISG LTKGFAFCTF SNKDEAQNAV KKLDNKEIRP GKRLGVCISV ANSRLFVGSI
PKTKSKQEIL EEFSKVTNGL DDVIVYLSAD QKGKNRGFAF LEYESHQAAS LARRRLASGR
IKVWGNIVVT VDWADPQEEP DDDAMKKVKV VYLRNLSPSI TEEKLKEEYS QYGAVDRVKK
LKDYAFVHFT ERDHALKAIE ETDGKEMDGL KIEASLAKPQ PGNKDRQRGQ SGFGSLNSRR
GGPRGYDGGY GQGGGYEGYS GGYRDDYGYG GGSYDHYDSY YGGGYDDYYG GGPPRGGPRG
GRGGSRGGPP RGAPRGRSGP PRGRGGGDFG GRGGRGGTTP GKRKYGADNP QGVVGYPEPK
KRFMAEGQQD YQGGGGWGSQ PISQQPQYSS YSDQGQEWYQ DSYGSEW
//
