ID   A7SJQ2_NEMVE            Unreviewed;       532 AA.
AC   A7SJQ2;
DT   02-OCT-2007, integrated into UniProtKB/TrEMBL.
DT   02-OCT-2007, sequence version 1.
DT   24-JAN-2024, entry version 87.
DE   RecName: Full=Glucosidase 2 subunit beta {ECO:0000256|ARBA:ARBA00022387};
GN   ORFNames=NEMVEDRAFT_v1g245724 {ECO:0000313|EMBL:EDO36083.1};
OS   Nematostella vectensis (Starlet sea anemone).
OC   Eukaryota; Metazoa; Cnidaria; Anthozoa; Hexacorallia; Actiniaria;
OC   Edwardsiidae; Nematostella.
OX   NCBI_TaxID=45351 {ECO:0000313|EMBL:EDO36083.1, ECO:0000313|Proteomes:UP000001593};
RN   [1] {ECO:0000313|EMBL:EDO36083.1, ECO:0000313|Proteomes:UP000001593}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CH2 X CH6 {ECO:0000313|Proteomes:UP000001593};
RX   PubMed=17615350; DOI=10.1126/science.1139158;
RA   Putnam N.H., Srivastava M., Hellsten U., Dirks B., Chapman J., Salamov A.,
RA   Terry A., Shapiro H., Lindquist E., Kapitonov V.V., Jurka J.,
RA   Genikhovich G., Grigoriev I.V., Lucas S.M., Steele R.E., Finnerty J.R.,
RA   Technau U., Martindale M.Q., Rokhsar D.S.;
RT   "Sea anemone genome reveals ancestral eumetazoan gene repertoire and
RT   genomic organization.";
RL   Science 317:86-94(2007).
CC   -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC       feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00124}.
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DR   EMBL; DS469679; EDO36083.1; -; Genomic_DNA.
DR   RefSeq; XP_001628146.1; XM_001628096.1.
DR   AlphaFoldDB; A7SJQ2; -.
DR   STRING; 45351.A7SJQ2; -.
DR   EnsemblMetazoa; EDO36083; EDO36083; NEMVEDRAFT_v1g245724.
DR   GeneID; 5507521; -.
DR   KEGG; nve:5507521; -.
DR   eggNOG; KOG2397; Eukaryota.
DR   HOGENOM; CLU_016834_1_0_1; -.
DR   InParanoid; A7SJQ2; -.
DR   OMA; YENGQHC; -.
DR   OrthoDB; 103990at2759; -.
DR   PhylomeDB; A7SJQ2; -.
DR   Proteomes; UP000001593; Unassembled WGS sequence.
DR   GO; GO:0017177; C:glucosidase II complex; IBA:GO_Central.
DR   GO; GO:0006491; P:N-glycan processing; IBA:GO_Central.
DR   CDD; cd00112; LDLa; 1.
DR   Gene3D; 4.10.400.10; Low-density Lipoprotein Receptor; 2.
DR   Gene3D; 2.70.130.10; Mannose-6-phosphate receptor binding domain; 1.
DR   InterPro; IPR018247; EF_Hand_1_Ca_BS.
DR   InterPro; IPR039794; Gtb1-like.
DR   InterPro; IPR036055; LDL_receptor-like_sf.
DR   InterPro; IPR002172; LDrepeatLR_classA_rpt.
DR   InterPro; IPR009011; Man6P_isomerase_rcpt-bd_dom_sf.
DR   InterPro; IPR044865; MRH_dom.
DR   InterPro; IPR036607; PRKCSH.
DR   InterPro; IPR028146; PRKCSH_N.
DR   PANTHER; PTHR12630:SF1; GLUCOSIDASE 2 SUBUNIT BETA; 1.
DR   PANTHER; PTHR12630; N-LINKED OLIGOSACCHARIDE PROCESSING; 1.
DR   Pfam; PF12999; PRKCSH-like; 1.
DR   Pfam; PF13015; PRKCSH_1; 1.
DR   SUPFAM; SSF50911; Mannose 6-phosphate receptor domain; 1.
DR   PROSITE; PS00018; EF_HAND_1; 1.
DR   PROSITE; PS50068; LDLRA_2; 1.
DR   PROSITE; PS51914; MRH; 1.
PE   4: Predicted;
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Disulfide bond {ECO:0000256|ARBA:ARBA00023157};
KW   Reference proteome {ECO:0000313|Proteomes:UP000001593};
KW   Signal {ECO:0000256|ARBA:ARBA00022729}.
FT   DOMAIN          423..523
FT                   /note="MRH"
FT                   /evidence="ECO:0000259|PROSITE:PS51914"
FT   REGION          286..376
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          158..205
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COMPBIAS        286..313
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        325..347
FT                   /note="Acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        348..376
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   532 AA;  59774 MW;  448DF266837C7772 CRC64;
     MAAACGAKNG VYLLLFTTIV SRLGSALTLR GVAITKLPFY DSSKDFTCLD GSLTIPFSSV
     NDDYCDCNDG SDEPGTAACP NGQFHCTNAG YRPKNYPSSR VNDGICDCCD GSDEYDGKVN
     CPDTCKELYK QEFEKRRHEI ELAKQGYAKK QEFSQDGINK KTERKKKLED LRLQLEQKKQ
     VVAELQATKD KVEAVEKEAK DKHDKEWEET KAKILAERAH NAAVAAFKLL DTDNSGSLTS
     MELMVNPYMD KEYTAEEARE LLGGTDETDV DRFAKDLWTT FKDKYGVKQE EKPIDASPPE
     DKPPTDEHPT ETPVDPHPTP PSIDDTIDDD ADLPEVGDDD DDEGDDLKDE AAARASDSKQ
     EEEPVKPEYD EETKAKITDA DNARKEFDAA DIAKRDIERE IGDIEKKLNI DFGEHEEFAA
     LYGNCFEFRD REYLYKLCPF DRATQEPKDG GASTSIGNWG EWNGSPYKYS RMKYSDGQNC
     WNGPNRSTQV ILSCGPDNEV TSVSEPSRCE YQMEFKTPAA CQHHEDILHQ EL
//