ID A7SM68_NEMVE Unreviewed; 487 AA.
AC A7SM68;
DT 02-OCT-2007, integrated into UniProtKB/TrEMBL.
DT 02-OCT-2007, sequence version 1.
DT 24-JAN-2024, entry version 66.
DE RecName: Full=SSD domain-containing protein {ECO:0000259|PROSITE:PS50156};
GN ORFNames=NEMVEDRAFT_v1g214420 {ECO:0000313|EMBL:EDO35179.1};
OS Nematostella vectensis (Starlet sea anemone).
OC Eukaryota; Metazoa; Cnidaria; Anthozoa; Hexacorallia; Actiniaria;
OC Edwardsiidae; Nematostella.
OX NCBI_TaxID=45351 {ECO:0000313|EMBL:EDO35179.1, ECO:0000313|Proteomes:UP000001593};
RN [1] {ECO:0000313|EMBL:EDO35179.1, ECO:0000313|Proteomes:UP000001593}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CH2 X CH6 {ECO:0000313|Proteomes:UP000001593};
RX PubMed=17615350; DOI=10.1126/science.1139158;
RA Putnam N.H., Srivastava M., Hellsten U., Dirks B., Chapman J., Salamov A.,
RA Terry A., Shapiro H., Lindquist E., Kapitonov V.V., Jurka J.,
RA Genikhovich G., Grigoriev I.V., Lucas S.M., Steele R.E., Finnerty J.R.,
RA Technau U., Martindale M.Q., Rokhsar D.S.;
RT "Sea anemone genome reveals ancestral eumetazoan gene repertoire and
RT genomic organization.";
RL Science 317:86-94(2007).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the dispatched family.
CC {ECO:0000256|ARBA:ARBA00038046}.
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DR EMBL; DS469706; EDO35179.1; -; Genomic_DNA.
DR RefSeq; XP_001627279.1; XM_001627229.1.
DR AlphaFoldDB; A7SM68; -.
DR STRING; 45351.A7SM68; -.
DR EnsemblMetazoa; EDO35179; EDO35179; NEMVEDRAFT_v1g214420.
DR eggNOG; KOG3664; Eukaryota.
DR HOGENOM; CLU_560561_0_0_1; -.
DR InParanoid; A7SM68; -.
DR PhylomeDB; A7SM68; -.
DR Proteomes; UP000001593; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IBA:GO_Central.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR GO; GO:0022857; F:transmembrane transporter activity; IBA:GO_Central.
DR GO; GO:0015074; P:DNA integration; IEA:InterPro.
DR GO; GO:0006310; P:DNA recombination; IEA:UniProtKB-KW.
DR GO; GO:0007224; P:smoothened signaling pathway; IBA:GO_Central.
DR Gene3D; 1.10.443.10; Intergrase catalytic core; 1.
DR Gene3D; 1.20.1640.10; Multidrug efflux transporter AcrB transmembrane domain; 1.
DR InterPro; IPR011010; DNA_brk_join_enz.
DR InterPro; IPR013762; Integrase-like_cat_sf.
DR InterPro; IPR003392; Ptc/Disp.
DR InterPro; IPR000731; SSD.
DR PANTHER; PTHR45951:SF3; PROTEIN DISPATCHED; 1.
DR PANTHER; PTHR45951; PROTEIN DISPATCHED-RELATED; 1.
DR Pfam; PF02460; Patched; 1.
DR SUPFAM; SSF56349; DNA breaking-rejoining enzymes; 1.
DR SUPFAM; SSF82866; Multidrug efflux transporter AcrB transmembrane domain; 1.
DR PROSITE; PS50156; SSD; 1.
PE 3: Inferred from homology;
KW DNA recombination {ECO:0000256|ARBA:ARBA00023172};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000001593};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 191..210
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 216..236
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 243..262
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 295..316
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 215..310
FT /note="SSD"
FT /evidence="ECO:0000259|PROSITE:PS50156"
SQ SEQUENCE 487 AA; 55282 MW; 2765E0DF2A5837D3 CRC64;
MTAESLKAVC RLESKIMRDF PGFREACFRR NITIHGLRKE ECCPSWSVGN YVASLSGRQT
CQDVTDEDVK EVMTRLKSCA KFFNNGTLKE NCWDYKNSLP YPYCVNIPLA CVKDNAVFII
FYYLTDKEFL GTDMQEHLSY TQAFTPRWHR GEYSKAIYYR YLEGKTMEDG PVRLVGTDFY
FLKFSMFNTK LLADIIYPSI ALMIILIIMW FYTESILITI LLAVSVVSAL ILAYFVNMII
LRLNFFPFLN ITTLIFLVGI GADDAFVFCD VWRQSKRDHP GASLKTVTYT TLRHASTSMF
VTSFTTAAAF VANMPLHVNH LRLIKKQNNV LGRRWRWKCL WGEKKSPAGD MPDTRYRAVT
PDLGVRDSSL SSSAAEARLK GYLKDLKAVE GETLHGIRAG CAITLALTGA DLSEIMDHIG
WSSRHTALYY MQLAKVLNRP AGASARLASE SHKGPLNVWQ DANELRRFVS ALPAACNESR
KRAHNPQ
//
