ID A7SM84_NEMVE Unreviewed; 754 AA.
AC A7SM84;
DT 02-OCT-2007, integrated into UniProtKB/TrEMBL.
DT 02-OCT-2007, sequence version 1.
DT 27-MAR-2024, entry version 62.
DE RecName: Full=Fibronectin type-II domain-containing protein {ECO:0000259|PROSITE:PS51092};
GN ORFNames=NEMVEDRAFT_v1g214437 {ECO:0000313|EMBL:EDO35188.1};
OS Nematostella vectensis (Starlet sea anemone).
OC Eukaryota; Metazoa; Cnidaria; Anthozoa; Hexacorallia; Actiniaria;
OC Edwardsiidae; Nematostella.
OX NCBI_TaxID=45351 {ECO:0000313|EMBL:EDO35188.1, ECO:0000313|Proteomes:UP000001593};
RN [1] {ECO:0000313|EMBL:EDO35188.1, ECO:0000313|Proteomes:UP000001593}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CH2 X CH6 {ECO:0000313|Proteomes:UP000001593};
RX PubMed=17615350; DOI=10.1126/science.1139158;
RA Putnam N.H., Srivastava M., Hellsten U., Dirks B., Chapman J., Salamov A.,
RA Terry A., Shapiro H., Lindquist E., Kapitonov V.V., Jurka J.,
RA Genikhovich G., Grigoriev I.V., Lucas S.M., Steele R.E., Finnerty J.R.,
RA Technau U., Martindale M.Q., Rokhsar D.S.;
RT "Sea anemone genome reveals ancestral eumetazoan gene repertoire and
RT genomic organization.";
RL Science 317:86-94(2007).
CC -!- SUBCELLULAR LOCATION: Secreted {ECO:0000256|ARBA:ARBA00004613}.
CC -!- SIMILARITY: Belongs to the seminal plasma protein family.
CC {ECO:0000256|ARBA:ARBA00010011}.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00479}.
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DR EMBL; DS469706; EDO35188.1; -; Genomic_DNA.
DR RefSeq; XP_001627288.1; XM_001627238.1.
DR AlphaFoldDB; A7SM84; -.
DR EnsemblMetazoa; EDO35188; EDO35188; NEMVEDRAFT_v1g214437.
DR eggNOG; KOG1565; Eukaryota.
DR HOGENOM; CLU_369323_0_0_1; -.
DR InParanoid; A7SM84; -.
DR Proteomes; UP000001593; Unassembled WGS sequence.
DR GO; GO:0009986; C:cell surface; IBA:GO_Central.
DR GO; GO:0046556; F:alpha-L-arabinofuranosidase activity; IEA:InterPro.
DR GO; GO:0008201; F:heparin binding; IBA:GO_Central.
DR GO; GO:0046373; P:L-arabinose metabolic process; IEA:InterPro.
DR CDD; cd00062; FN2; 1.
DR Gene3D; 2.80.10.50; -; 1.
DR Gene3D; 2.10.10.10; Fibronectin, type II, collagen-binding; 1.
DR InterPro; IPR007934; AbfB_ABD.
DR InterPro; IPR036195; AbfB_ABD_sf.
DR InterPro; IPR000562; FN_type2_dom.
DR InterPro; IPR036943; FN_type2_sf.
DR InterPro; IPR013806; Kringle-like.
DR PANTHER; PTHR22918:SF1; FEMALE STERILE (1) M3; 1.
DR PANTHER; PTHR22918; SEMINAL PLASMA PROTEIN; 1.
DR Pfam; PF05270; AbfB; 1.
DR Pfam; PF00040; fn2; 1.
DR PRINTS; PR00013; FNTYPEII.
DR SMART; SM00059; FN2; 1.
DR SUPFAM; SSF110221; AbfB domain; 1.
DR SUPFAM; SSF57440; Kringle-like; 1.
DR PROSITE; PS00023; FN2_1; 1.
DR PROSITE; PS51092; FN2_2; 1.
PE 3: Inferred from homology;
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157};
KW Reference proteome {ECO:0000313|Proteomes:UP000001593}.
FT DOMAIN 648..695
FT /note="Fibronectin type-II"
FT /evidence="ECO:0000259|PROSITE:PS51092"
FT REGION 234..263
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 239..263
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 754 AA; 83464 MW; DEC3F14F597C42A4 CRC64;
MWLCGSVEAS LFAFLAYYSS FISVNTLPVG KNITLTKLYS VRFEDIADLS EGVTGDFGNL
GINAQLDQAS LAEKVTEFRL HRPGFQHVPH SISLESNAEP GLFLRYKNYK FHLEKAKPTG
LFEKDATFVE RQPVGPHSIS LELFTHPGWF LCHETDAPFV LKATSKVVGS KEFDQKCVFR
PVVRTPGTRL TTKTIITPKP LTDERQKELK AAEAAKLLDS LVAKESAGEI MAAKPTASTP
AATKANDKTN GITSTASTPA ATKANDKTND ITLKPAVKKI SGQIISYRGS GAVNPRLLQY
HTGNQAVPRG GARLLSPQRY QRPYGYGLAG AKGPVIKPYG PAYGPRTTST GRLYLGQQQY
KQNMRGANAK YVQAYNQKPA NQYNIRGGGW GRMSATNYAR KGNYRQAIYP QGFLAQTLNQ
LSSASTMRTA KPYVQRPKPV PYRPPINRAY SAPARTTLAA KQQTPPSQQV KGSSSVAITS
GLGSGVALSY HHPKEPKPVD PKLATVDKGD KCIGLKFFNK LRRPVKIISS MKMAGYLVTA
ETFKLKTIFK HSRRNRKVIF YAQDLDDKEE VLLNNNNVVT VIPGPCDMPY RQLYITRPGQ
FTNRAIEDLL KQGPASTRSV VQSSPTGGFG QWSAFEPQCV QTYGGNSNVG KCCSLPFIFR
DTVYDKCIKH THTGNMWCAT TPNYDQDRTW GFCKQTEIMD YNGNKNMTIT DYHMSLAREQ
LQRFVKQLDY GTSLKGVPRI TNIDGIRLPN MNQT
//
