ID A7SNT9_NEMVE Unreviewed; 407 AA.
AC A7SNT9;
DT 02-OCT-2007, integrated into UniProtKB/TrEMBL.
DT 02-OCT-2007, sequence version 1.
DT 27-MAR-2024, entry version 70.
DE RecName: Full=Major facilitator superfamily domain-containing protein 12 {ECO:0008006|Google:ProtNLM};
GN ORFNames=NEMVEDRAFT_v1g246446 {ECO:0000313|EMBL:EDO34621.1};
OS Nematostella vectensis (Starlet sea anemone).
OC Eukaryota; Metazoa; Cnidaria; Anthozoa; Hexacorallia; Actiniaria;
OC Edwardsiidae; Nematostella.
OX NCBI_TaxID=45351 {ECO:0000313|EMBL:EDO34621.1, ECO:0000313|Proteomes:UP000001593};
RN [1] {ECO:0000313|EMBL:EDO34621.1, ECO:0000313|Proteomes:UP000001593}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CH2 X CH6 {ECO:0000313|Proteomes:UP000001593};
RX PubMed=17615350; DOI=10.1126/science.1139158;
RA Putnam N.H., Srivastava M., Hellsten U., Dirks B., Chapman J., Salamov A.,
RA Terry A., Shapiro H., Lindquist E., Kapitonov V.V., Jurka J.,
RA Genikhovich G., Grigoriev I.V., Lucas S.M., Steele R.E., Finnerty J.R.,
RA Technau U., Martindale M.Q., Rokhsar D.S.;
RT "Sea anemone genome reveals ancestral eumetazoan gene repertoire and
RT genomic organization.";
RL Science 317:86-94(2007).
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DR EMBL; DS469724; EDO34621.1; -; Genomic_DNA.
DR RefSeq; XP_001626721.1; XM_001626671.1.
DR AlphaFoldDB; A7SNT9; -.
DR STRING; 45351.A7SNT9; -.
DR EnsemblMetazoa; EDO34621; EDO34621; NEMVEDRAFT_v1g246446.
DR GeneID; 5505964; -.
DR KEGG; nve:5505964; -.
DR eggNOG; KOG4830; Eukaryota.
DR HOGENOM; CLU_030068_1_1_1; -.
DR InParanoid; A7SNT9; -.
DR OMA; GLYTAWM; -.
DR OrthoDB; 2902828at2759; -.
DR PhylomeDB; A7SNT9; -.
DR Proteomes; UP000001593; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0015293; F:symporter activity; IEA:InterPro.
DR GO; GO:0008643; P:carbohydrate transport; IEA:InterPro.
DR GO; GO:0071702; P:organic substance transport; IBA:GO_Central.
DR CDD; cd17491; MFS_MFSD12; 1.
DR Gene3D; 1.20.1250.20; MFS general substrate transporter like domains; 2.
DR InterPro; IPR039672; MFS_2.
DR InterPro; IPR036259; MFS_trans_sf.
DR PANTHER; PTHR11328; MAJOR FACILITATOR SUPERFAMILY DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR11328:SF28; MAJOR FACILITATOR SUPERFAMILY DOMAIN-CONTAINING PROTEIN 12; 1.
DR Pfam; PF13347; MFS_2; 1.
DR SUPFAM; SSF103473; MFS general substrate transporter; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000001593};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 15..39
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 45..64
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 85..102
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 114..136
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 157..177
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 197..215
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 257..276
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 288..306
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 318..337
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 343..364
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
SQ SEQUENCE 407 AA; 45251 MW; C3CE80B323C7399F CRC64;
MDGISPNSLS FRAKFCYGVG HILNDLCASM WFTYLLVYLH KVVKFSNLAA GALLLIGQVA
DAIATPIVGI ESDRTHNCAY GRRKIWHLIG VLCVTLTFPF IFNLCITCEN SSTWALFVYY
TPFIIIFQFG WASTQISHLS LIPELTSDEH AKTTLNTIRY GCTVTSNIFV FCVAWFLFET
VGAKDTDNLS QKDAPAFMYL VFVLVGTGLV FMVIFHAGVK EPHRTCTYAL ASCKKSKRSA
SNWTSWFREH QFYQVGLLYM CTRLIVNITQ VYLPMYLISS LELSKSTIAI MPLIVFSSGF
VATFLAKPTI HYLGRKGTHL IGLIIILGVS VWFWFLTPNT SQIYGTSVFL GIGGSLLLVT
ALTLTADLIG NNKETGAFVY GAMSFVDKLS NGIAVQLIQA LHPCRDE
//
