ID A7SSW1_NEMVE Unreviewed; 480 AA.
AC A7SSW1;
DT 02-OCT-2007, integrated into UniProtKB/TrEMBL.
DT 02-OCT-2007, sequence version 1.
DT 27-MAR-2024, entry version 65.
DE RecName: Full=Major facilitator superfamily (MFS) profile domain-containing protein {ECO:0000259|PROSITE:PS50850};
GN ORFNames=NEMVEDRAFT_v1g247209 {ECO:0000313|EMBL:EDO33207.1};
OS Nematostella vectensis (Starlet sea anemone).
OC Eukaryota; Metazoa; Cnidaria; Anthozoa; Hexacorallia; Actiniaria;
OC Edwardsiidae; Nematostella.
OX NCBI_TaxID=45351 {ECO:0000313|EMBL:EDO33207.1, ECO:0000313|Proteomes:UP000001593};
RN [1] {ECO:0000313|EMBL:EDO33207.1, ECO:0000313|Proteomes:UP000001593}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CH2 X CH6 {ECO:0000313|Proteomes:UP000001593};
RX PubMed=17615350; DOI=10.1126/science.1139158;
RA Putnam N.H., Srivastava M., Hellsten U., Dirks B., Chapman J., Salamov A.,
RA Terry A., Shapiro H., Lindquist E., Kapitonov V.V., Jurka J.,
RA Genikhovich G., Grigoriev I.V., Lucas S.M., Steele R.E., Finnerty J.R.,
RA Technau U., Martindale M.Q., Rokhsar D.S.;
RT "Sea anemone genome reveals ancestral eumetazoan gene repertoire and
RT genomic organization.";
RL Science 317:86-94(2007).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the major facilitator superfamily. MFSD6 family.
CC {ECO:0000256|ARBA:ARBA00005241}.
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DR EMBL; DS469784; EDO33207.1; -; Genomic_DNA.
DR RefSeq; XP_001625307.1; XM_001625257.1.
DR AlphaFoldDB; A7SSW1; -.
DR EnsemblMetazoa; EDO33207; EDO33207; NEMVEDRAFT_v1g247209.
DR GeneID; 5504413; -.
DR KEGG; nve:5504413; -.
DR eggNOG; KOG3762; Eukaryota.
DR HOGENOM; CLU_013133_2_1_1; -.
DR InParanoid; A7SSW1; -.
DR OMA; FIMATCF; -.
DR OrthoDB; 1365658at2759; -.
DR PhylomeDB; A7SSW1; -.
DR Proteomes; UP000001593; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IBA:GO_Central.
DR GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
DR CDD; cd17335; MFS_MFSD6; 1.
DR Gene3D; 1.20.1250.20; MFS general substrate transporter like domains; 2.
DR InterPro; IPR024989; MFS_assoc_dom.
DR InterPro; IPR020846; MFS_dom.
DR InterPro; IPR036259; MFS_trans_sf.
DR PANTHER; PTHR16172:SF41; MFS_1_LIKE DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR16172; UNCHARACTERIZED; 1.
DR Pfam; PF12832; MFS_1_like; 1.
DR SUPFAM; SSF103473; MFS general substrate transporter; 1.
DR PROSITE; PS50850; MFS; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000001593};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 31..51
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 57..79
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 91..117
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 137..165
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 177..194
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 220..238
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 259..290
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 296..317
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 329..349
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 361..380
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 392..415
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 421..441
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 265..480
FT /note="Major facilitator superfamily (MFS) profile"
FT /evidence="ECO:0000259|PROSITE:PS50850"
SQ SEQUENCE 480 AA; 53662 MW; 12DE307C88D26230 CRC64;
MTRLVREQLP LREIPNTSLL HINPRTMKYK LFYFAFFFGS ATIKTFLPVY FRFVGLGAVL
TSVLTSVRPF TRLVSYPLFS GIADKTGKRK LILMASLIVS VLAYFSLSFV MIVQQVSHQG
AFAYPNTTAS DLSENTIFWT SLLLVGLGDF FSAPVTVIMS GTIIYWEGTS AFGKQRVFGA
LGFGLGSYLS GLAIDETSGF NYFHPSSPHA LQSGTEKPNY LTAFFMFLVV NVFLIMLVKF
QFELKTERRP KFVVGHLRIL LRESAVLCFL GYIFVMGISG GVIMLFLFWF LEDLGASQAL
LGLASLVMSL SEIPVFPAAS HLIKRYGHVG VLFLSLTCFI IRLVCYTFLH DPWYVLLIEP
LHGITLAIMW STCVSFASVV SPPEIYTSME GVIAGVHYGL GWGLGVVIGG WFYHAYGVRN
LFRFCLGLCC LCFPLLGVVY VKVKRDSTGN VVRYRTLDSL SHDQRIVTQE YQLITGNTYI
//
