ID A7SSX9_NEMVE Unreviewed; 119 AA.
AC A7SSX9;
DT 02-OCT-2007, integrated into UniProtKB/TrEMBL.
DT 02-OCT-2007, sequence version 1.
DT 27-MAR-2024, entry version 57.
DE RecName: Full=Fucolectin tachylectin-4 pentraxin-1 domain-containing protein {ECO:0000259|SMART:SM00607};
DE Flags: Fragment;
GN ORFNames=NEMVEDRAFT_v1g130395 {ECO:0000313|EMBL:EDO33194.1};
OS Nematostella vectensis (Starlet sea anemone).
OC Eukaryota; Metazoa; Cnidaria; Anthozoa; Hexacorallia; Actiniaria;
OC Edwardsiidae; Nematostella.
OX NCBI_TaxID=45351 {ECO:0000313|EMBL:EDO33194.1, ECO:0000313|Proteomes:UP000001593};
RN [1] {ECO:0000313|EMBL:EDO33194.1, ECO:0000313|Proteomes:UP000001593}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CH2 X CH6 {ECO:0000313|Proteomes:UP000001593};
RX PubMed=17615350; DOI=10.1126/science.1139158;
RA Putnam N.H., Srivastava M., Hellsten U., Dirks B., Chapman J., Salamov A.,
RA Terry A., Shapiro H., Lindquist E., Kapitonov V.V., Jurka J.,
RA Genikhovich G., Grigoriev I.V., Lucas S.M., Steele R.E., Finnerty J.R.,
RA Technau U., Martindale M.Q., Rokhsar D.S.;
RT "Sea anemone genome reveals ancestral eumetazoan gene repertoire and
RT genomic organization.";
RL Science 317:86-94(2007).
CC -!- FUNCTION: Acts as a defensive agent. Recognizes blood group fucosylated
CC oligosaccharides including A, B, H and Lewis B-type antigens. Does not
CC recognize Lewis A antigen and has low affinity for monovalent haptens.
CC {ECO:0000256|ARBA:ARBA00002219}.
CC -!- SUBUNIT: Homotrimer. {ECO:0000256|ARBA:ARBA00011233}.
CC -!- SIMILARITY: Belongs to the fucolectin family.
CC {ECO:0000256|ARBA:ARBA00010147}.
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DR EMBL; DS469785; EDO33194.1; -; Genomic_DNA.
DR RefSeq; XP_001625294.1; XM_001625244.1.
DR AlphaFoldDB; A7SSX9; -.
DR EnsemblMetazoa; EDO33194; EDO33194; NEMVEDRAFT_v1g130395.
DR GeneID; 5504381; -.
DR KEGG; nve:5504381; -.
DR eggNOG; ENOG502SE8Y; Eukaryota.
DR HOGENOM; CLU_072164_2_1_1; -.
DR InParanoid; A7SSX9; -.
DR OMA; HTATENN; -.
DR OrthoDB; 3970515at2759; -.
DR PhylomeDB; A7SSX9; -.
DR Proteomes; UP000001593; Unassembled WGS sequence.
DR GO; GO:0042806; F:fucose binding; IEA:UniProt.
DR GO; GO:0010185; P:regulation of cellular defense response; IEA:UniProt.
DR GO; GO:0001868; P:regulation of complement activation, lectin pathway; IEA:UniProt.
DR Gene3D; 2.60.120.260; Galactose-binding domain-like; 1.
DR InterPro; IPR000421; FA58C.
DR InterPro; IPR006585; FTP1.
DR InterPro; IPR008979; Galactose-bd-like_sf.
DR PANTHER; PTHR45713:SF6; F5_8 TYPE C DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR45713; FTP DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF00754; F5_F8_type_C; 1.
DR SMART; SM00607; FTP; 1.
DR SUPFAM; SSF49785; Galactose-binding domain-like; 1.
PE 3: Inferred from homology;
KW Lectin {ECO:0000256|ARBA:ARBA00022734};
KW Reference proteome {ECO:0000313|Proteomes:UP000001593}.
FT DOMAIN 1..118
FT /note="Fucolectin tachylectin-4 pentraxin-1"
FT /evidence="ECO:0000259|SMART:SM00607"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:EDO33194.1"
FT NON_TER 119
FT /evidence="ECO:0000313|EMBL:EDO33194.1"
SQ SEQUENCE 119 AA; 13359 MW; 4BA3A940C825A386 CRC64;
AEHAVDGNRS GRFSDLSCTE TKVQSNPWWR VDLQKSYVIL RLFIVNRADC CGERLDNFEI
RIGDSLENNG TDNPSCGSSY IIPHGGSKSI SCHTLLKGRY VNIWIPGSDR RLTLCEVEV
//
