ID   A7SVC1_NEMVE            Unreviewed;       745 AA.
AC   A7SVC1;
DT   02-OCT-2007, integrated into UniProtKB/TrEMBL.
DT   02-OCT-2007, sequence version 1.
DT   27-MAR-2024, entry version 55.
DE   RecName: Full=DUF4062 domain-containing protein {ECO:0000259|Pfam:PF13271};
GN   ORFNames=NEMVEDRAFT_v1g133949 {ECO:0000313|EMBL:EDO32345.1};
OS   Nematostella vectensis (Starlet sea anemone).
OC   Eukaryota; Metazoa; Cnidaria; Anthozoa; Hexacorallia; Actiniaria;
OC   Edwardsiidae; Nematostella.
OX   NCBI_TaxID=45351 {ECO:0000313|EMBL:EDO32345.1, ECO:0000313|Proteomes:UP000001593};
RN   [1] {ECO:0000313|EMBL:EDO32345.1, ECO:0000313|Proteomes:UP000001593}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CH2 X CH6 {ECO:0000313|Proteomes:UP000001593};
RX   PubMed=17615350; DOI=10.1126/science.1139158;
RA   Putnam N.H., Srivastava M., Hellsten U., Dirks B., Chapman J., Salamov A.,
RA   Terry A., Shapiro H., Lindquist E., Kapitonov V.V., Jurka J.,
RA   Genikhovich G., Grigoriev I.V., Lucas S.M., Steele R.E., Finnerty J.R.,
RA   Technau U., Martindale M.Q., Rokhsar D.S.;
RT   "Sea anemone genome reveals ancestral eumetazoan gene repertoire and
RT   genomic organization.";
RL   Science 317:86-94(2007).
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DR   EMBL; DS469831; EDO32345.1; -; Genomic_DNA.
DR   RefSeq; XP_001624445.1; XM_001624395.1.
DR   AlphaFoldDB; A7SVC1; -.
DR   STRING; 45351.A7SVC1; -.
DR   EnsemblMetazoa; EDO32345; EDO32345; NEMVEDRAFT_v1g133949.
DR   eggNOG; KOG3602; Eukaryota.
DR   HOGENOM; CLU_373248_0_0_1; -.
DR   InParanoid; A7SVC1; -.
DR   OMA; GCETISI; -.
DR   PhylomeDB; A7SVC1; -.
DR   Proteomes; UP000001593; Unassembled WGS sequence.
DR   GO; GO:0080008; C:Cul4-RING E3 ubiquitin ligase complex; IBA:GO_Central.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR   InterPro; IPR025139; DUF4062.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   PANTHER; PTHR19860; DDB1- AND CUL4-ASSOCIATED FACTOR 12-RELATED; 1.
DR   PANTHER; PTHR19860:SF43; DUF4062 DOMAIN-CONTAINING PROTEIN; 1.
DR   Pfam; PF13271; DUF4062; 1.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000001593};
KW   Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT   DOMAIN          7..90
FT                   /note="DUF4062"
FT                   /evidence="ECO:0000259|Pfam:PF13271"
FT   NON_TER         1
FT                   /evidence="ECO:0000313|EMBL:EDO32345.1"
SQ   SEQUENCE   745 AA;  84601 MW;  3E1ECFB092B8718C CRC64;
     MLRKTARVFF SSPFGGLEEE REELTKKYWP QLESMCSKAG YEFIPVDLRW GITSEMSSSA
     VTIKVCLSEM DRSDMIVGFF GQRYGWHGNN ELLQKSFDVA AVKYPWVNEY RDRAVTELEF
     LHGHLRNPGA RPACFFFRDK VRYYDAILGK NACSPNQPQA QKMNTTIENH ARLGGKQKKT
     CTTCLAVHMS YATPQEGARL MFETIKKYFN EVLLAFPAES LKEQDLENVQ HDVFLASRLG
     MGGAYVGGAK YISMIDRHLS TKGQSRPIVV LGNAGDGKSC LLSNWITAHQ LRHPTDVIVY
     HFVGSSSEST VPKFLLSRLV NELFEEVQEK QINNNVTFGP LDEGLRAASS DNEPDLIRKI
     RALTAKLTET GASVFLVVDA LNKVDVTGQT MKALYWLPKD LPHGAHLVAS TLASDTANIR
     ELETRGCETI SIAALQHSER EEIALATLKI RGKTLSTQQR ERIFQKQQTQ NPLYLKTLLQ
     ELLSFGEFFQ LDAYIDDLLE ANDTKGLFTK FLKRLETDYN PEDFDGNLIE QVLSCILVCR
     QGLSENELKS ILQISDQNWS ALYFALDDFL VFRSGLYNFA YDELRDAVQE RYCQSSEKRK
     EFIVKVVNYF EEKLGGRSLM YDTTIPTRVL KELPWLLKNL GDSDRLVACL LHPAVFYSLR
     SGLDQYDLAN YWAVSGLDGD TIVAKQKKVI DDQMILFYNE AIDKGNDQKS ALRKMSHFVY
     ELAQFLENAG YLSSVEPLLE RALQM
//