ID A7T3W1_NEMVE Unreviewed; 1214 AA.
AC A7T3W1;
DT 02-OCT-2007, integrated into UniProtKB/TrEMBL.
DT 02-OCT-2007, sequence version 1.
DT 24-JAN-2024, entry version 74.
DE RecName: Full=CHAT domain-containing protein {ECO:0000259|Pfam:PF12770};
GN ORFNames=NEMVEDRAFT_v1g221977 {ECO:0000313|EMBL:EDO29351.1};
OS Nematostella vectensis (Starlet sea anemone).
OC Eukaryota; Metazoa; Cnidaria; Anthozoa; Hexacorallia; Actiniaria;
OC Edwardsiidae; Nematostella.
OX NCBI_TaxID=45351 {ECO:0000313|EMBL:EDO29351.1, ECO:0000313|Proteomes:UP000001593};
RN [1] {ECO:0000313|EMBL:EDO29351.1, ECO:0000313|Proteomes:UP000001593}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CH2 X CH6 {ECO:0000313|Proteomes:UP000001593};
RX PubMed=17615350; DOI=10.1126/science.1139158;
RA Putnam N.H., Srivastava M., Hellsten U., Dirks B., Chapman J., Salamov A.,
RA Terry A., Shapiro H., Lindquist E., Kapitonov V.V., Jurka J.,
RA Genikhovich G., Grigoriev I.V., Lucas S.M., Steele R.E., Finnerty J.R.,
RA Technau U., Martindale M.Q., Rokhsar D.S.;
RT "Sea anemone genome reveals ancestral eumetazoan gene repertoire and
RT genomic organization.";
RL Science 317:86-94(2007).
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DR EMBL; DS470663; EDO29351.1; -; Genomic_DNA.
DR RefSeq; XP_001621451.1; XM_001621401.1.
DR AlphaFoldDB; A7T3W1; -.
DR STRING; 45351.A7T3W1; -.
DR EnsemblMetazoa; EDO29351; EDO29351; NEMVEDRAFT_v1g221977.
DR eggNOG; KOG0548; Eukaryota.
DR HOGENOM; CLU_002404_0_1_1; -.
DR InParanoid; A7T3W1; -.
DR OMA; TYRCLFR; -.
DR PhylomeDB; A7T3W1; -.
DR Proteomes; UP000001593; Unassembled WGS sequence.
DR Gene3D; 1.25.40.10; Tetratricopeptide repeat domain; 3.
DR InterPro; IPR024983; CHAT_dom.
DR InterPro; IPR011990; TPR-like_helical_dom_sf.
DR InterPro; IPR019734; TPR_repeat.
DR PANTHER; PTHR10098; RAPSYN-RELATED; 1.
DR PANTHER; PTHR10098:SF106; TETRATRICOPEPTIDE REPEAT PROTEIN 28; 1.
DR Pfam; PF12770; CHAT; 1.
DR Pfam; PF14938; SNAP; 1.
DR Pfam; PF13374; TPR_10; 1.
DR Pfam; PF13424; TPR_12; 3.
DR SMART; SM00028; TPR; 18.
DR SUPFAM; SSF81901; HCP-like; 1.
DR SUPFAM; SSF48452; TPR-like; 3.
DR PROSITE; PS50005; TPR; 14.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000001593};
KW TPR repeat {ECO:0000256|PROSITE-ProRule:PRU00339}.
FT REPEAT 109..142
FT /note="TPR"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
FT REPEAT 149..182
FT /note="TPR"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
FT REPEAT 189..222
FT /note="TPR"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
FT REPEAT 229..262
FT /note="TPR"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
FT REPEAT 269..302
FT /note="TPR"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
FT REPEAT 309..342
FT /note="TPR"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
FT REPEAT 349..382
FT /note="TPR"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
FT REPEAT 389..422
FT /note="TPR"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
FT REPEAT 593..626
FT /note="TPR"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
FT REPEAT 633..666
FT /note="TPR"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
FT REPEAT 673..706
FT /note="TPR"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
FT REPEAT 713..746
FT /note="TPR"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
FT REPEAT 753..786
FT /note="TPR"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
FT REPEAT 832..865
FT /note="TPR"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
FT DOMAIN 1138..1211
FT /note="CHAT"
FT /evidence="ECO:0000259|Pfam:PF12770"
FT REGION 562..587
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1023..1106
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1113..1132
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 567..587
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1045..1065
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1066..1105
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:EDO29351.1"
SQ SEQUENCE 1214 AA; 136987 MW; 59AE2D002D515AA8 CRC64;
MDNEGEPFTH WDVAELERVQ RVRPNLPVIF CFLLIWGTEI SPLTPAQQIQ LLKVCYDIAF
LLRDSEMMVA VYGSAGKVYR EMRLFDQALA CLSTALEIAK AIGSIELQAK CYNDMGSTYI
KLHNYNKALD YYKQSLNAYM KTGEERGQAN VYKNIGTLYM TLGDNGQAMV NYKNALCIHE
KFGEEREQAD VYSNIGNTYY SLGDNGQAMV NYKHALCIYE KFGEERKQAD VYNNIGVVFM
SLGDNGKAME NYKNALCIYE KFGEECKQAN VYSNIGNTYY SLGDNGQAMV NYKHALCIYE
KFGEELKQAD VYNNIGAVFM SLGDNGQAME NYKHALCIHE KFGEELKQAD VYFKIGAVFK
SLGDNGQAME NYKHALCILE KFGEECRQAD VYNNIGAVFY SLGDDGQAMM NYKKALCIFR
KFEKEHGLAT ACGNIANIAR FYNPVEAMEL YRSALAIFQK HGDVIGQAET WHNIGFLYLN
MSEDPEAEKS LKESLRLFEL VFMNFGSLEK LKITVIETYI KTYRCLFRVS IILDKPEQAL
LASEQGRSRA LKDSLQKKYG LESNAPSDED TRYTSSLISE DNTSSLGKSC KQADVYSNIG
NIYKSLGDNG QAMVNYKHAL CIHEKFGEEL KQADVYFNIG AVFKSLGDNG QAMENYKHAL
CIHEKFGEER KQADVYSNIG AVFKSLGDNG QAMENYKHAL CIHEKFGEER KQADVYFKIG
AVFKSLGDNG QAMENYKHAL CILEKFGEEC RQADVYNNIG AVFYSLGDDG QAMMNYKKAL
CIFRKFEKEH GLATACGNIA NIARFDNPVE AMELYRSALA IFQKHGDVIL QAETWHNIGI
VYLNMSEDPE AEKSLKESLR LFELVFMNLG SLEKLKITVI ETYIKTYRCL FRVSIILDKP
EQALLASEQG RSRALKDSLQ KKYGLESNAP SDEDTRFTSS LISEDNTSFV VICLSLEWLH
LFTLASGKPL VTESVPKEIF SSVESEINGK EWLRDYIDRM VNEANAHVRL NRDESFEDRS
LRLSCDDDGD ESRQPSVLAR GVRTATEIER ARKSTEVRAE PSENSEDGNF PETSSTNSQA
TGGTQNQPQL PTQAPMSQAT GIPQKSDEIP SVKVPQEHED DTCTPLLPSG PETPIHHDPL
EVLYRLLISP IEDHLTGPEV VFIPEDFTFK IPFGAMKDPD GRFLAERKRI RTGPSLSTLK
LLRECPEHKH SKQS
//
