ID A7T4F7_NEMVE Unreviewed; 127 AA.
AC A7T4F7;
DT 02-OCT-2007, integrated into UniProtKB/TrEMBL.
DT 02-OCT-2007, sequence version 1.
DT 27-MAR-2024, entry version 71.
DE RecName: Full=EGF-like domain-containing protein {ECO:0000259|PROSITE:PS50026};
DE Flags: Fragment;
GN ORFNames=NEMVEDRAFT_v1g145544 {ECO:0000313|EMBL:EDO29156.1};
OS Nematostella vectensis (Starlet sea anemone).
OC Eukaryota; Metazoa; Cnidaria; Anthozoa; Hexacorallia; Actiniaria;
OC Edwardsiidae; Nematostella.
OX NCBI_TaxID=45351 {ECO:0000313|EMBL:EDO29156.1, ECO:0000313|Proteomes:UP000001593};
RN [1] {ECO:0000313|EMBL:EDO29156.1, ECO:0000313|Proteomes:UP000001593}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CH2 X CH6 {ECO:0000313|Proteomes:UP000001593};
RX PubMed=17615350; DOI=10.1126/science.1139158;
RA Putnam N.H., Srivastava M., Hellsten U., Dirks B., Chapman J., Salamov A.,
RA Terry A., Shapiro H., Lindquist E., Kapitonov V.V., Jurka J.,
RA Genikhovich G., Grigoriev I.V., Lucas S.M., Steele R.E., Finnerty J.R.,
RA Technau U., Martindale M.Q., Rokhsar D.S.;
RT "Sea anemone genome reveals ancestral eumetazoan gene repertoire and
RT genomic organization.";
RL Science 317:86-94(2007).
CC -!- SIMILARITY: Belongs to the EGF domain peptide family.
CC {ECO:0000256|ARBA:ARBA00006373}.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00076}.
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DR EMBL; DS470864; EDO29156.1; -; Genomic_DNA.
DR RefSeq; XP_001621256.1; XM_001621206.1.
DR AlphaFoldDB; A7T4F7; -.
DR STRING; 45351.A7T4F7; -.
DR eggNOG; KOG1217; Eukaryota.
DR HOGENOM; CLU_004826_6_0_1; -.
DR InParanoid; A7T4F7; -.
DR OMA; INECNSR; -.
DR PhylomeDB; A7T4F7; -.
DR Proteomes; UP000001593; Unassembled WGS sequence.
DR GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR CDD; cd00054; EGF_CA; 3.
DR Gene3D; 2.10.25.10; Laminin; 3.
DR InterPro; IPR001881; EGF-like_Ca-bd_dom.
DR InterPro; IPR000742; EGF-like_dom.
DR PANTHER; PTHR24044:SF514; ANTERIOR PHARYNX IN EXCESS PROTEIN 1-RELATED; 1.
DR PANTHER; PTHR24044; NOTCH LIGAND FAMILY MEMBER; 1.
DR Pfam; PF00008; EGF; 3.
DR SMART; SM00181; EGF; 3.
DR SMART; SM00179; EGF_CA; 3.
DR SUPFAM; SSF57196; EGF/Laminin; 3.
DR PROSITE; PS00022; EGF_1; 3.
DR PROSITE; PS01186; EGF_2; 3.
DR PROSITE; PS50026; EGF_3; 3.
PE 3: Inferred from homology;
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157, ECO:0000256|PROSITE-
KW ProRule:PRU00076}; EGF-like domain {ECO:0000256|PROSITE-ProRule:PRU00076};
KW Reference proteome {ECO:0000313|Proteomes:UP000001593};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Signal {ECO:0000256|ARBA:ARBA00022729}.
FT DOMAIN 1..38
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 40..78
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 80..118
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DISULFID 9..26
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT DISULFID 28..37
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT DISULFID 49..66
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT DISULFID 68..77
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT DISULFID 89..106
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT DISULFID 108..117
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT NON_TER 127
FT /evidence="ECO:0000313|EMBL:EDO29156.1"
SQ SEQUENCE 127 AA; 13378 MW; 6F48361CC6C75E31 CRC64;
VKSCDSSPCK NNATCINKED NSGYNCTCSA GFTGSDCETQ VKPCDSSPCK NNATCINDKD
NSGYNCTCSA GFTGSDCETQ VKPCDSSPCK NNATCTNKED NSGYNCTCSA GFTGNDCITQ
GSYYMKK
//
