ID A7TF61_VANPO Unreviewed; 480 AA.
AC A7TF61;
DT 02-OCT-2007, integrated into UniProtKB/TrEMBL.
DT 02-OCT-2007, sequence version 1.
DT 27-MAR-2024, entry version 71.
DE SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:EDO19086.1};
GN ORFNames=Kpol_2000p53 {ECO:0000313|EMBL:EDO19086.1};
OS Vanderwaltozyma polyspora (strain ATCC 22028 / DSM 70294 / BCRC 21397 / CBS
OS 2163 / NBRC 10782 / NRRL Y-8283 / UCD 57-17) (Kluyveromyces polysporus).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Saccharomycetaceae; Vanderwaltozyma.
OX NCBI_TaxID=436907 {ECO:0000313|Proteomes:UP000000267};
RN [1] {ECO:0000313|EMBL:EDO19086.1, ECO:0000313|Proteomes:UP000000267}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 22028 / DSM 70294 / BCRC 21397 / CBS 2163 / NBRC 10782 /
RC NRRL Y-8283 / UCD 57-17 {ECO:0000313|Proteomes:UP000000267};
RX PubMed=17494770; DOI=10.1073/pnas.0608218104;
RA Scannell D.R., Frank A.C., Conant G.C., Byrne K.P., Woolfit M., Wolfe K.H.;
RT "Independent sorting-out of thousands of duplicated gene pairs in two yeast
RT species descended from a whole-genome duplication.";
RL Proc. Natl. Acad. Sci. U.S.A. 104:8397-8402(2007).
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC -!- SIMILARITY: Belongs to the ORC5 family.
CC {ECO:0000256|ARBA:ARBA00006269}.
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DR EMBL; DS480382; EDO19086.1; -; Genomic_DNA.
DR RefSeq; XP_001646944.1; XM_001646894.1.
DR AlphaFoldDB; A7TF61; -.
DR STRING; 436907.A7TF61; -.
DR GeneID; 5547414; -.
DR KEGG; vpo:Kpol_2000p53; -.
DR eggNOG; KOG2543; Eukaryota.
DR HOGENOM; CLU_028223_2_1_1; -.
DR InParanoid; A7TF61; -.
DR OMA; AYICSYL; -.
DR OrthoDB; 469431at2759; -.
DR PhylomeDB; A7TF61; -.
DR Proteomes; UP000000267; Unassembled WGS sequence.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0000808; C:origin recognition complex; IEA:InterPro.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0006260; P:DNA replication; IEA:UniProtKB-KW.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR041664; AAA_16.
DR InterPro; IPR020796; ORC5.
DR InterPro; IPR047088; ORC5_C.
DR InterPro; IPR048866; ORC5_lid.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR12705; ORIGIN RECOGNITION COMPLEX SUBUNIT 5; 1.
DR PANTHER; PTHR12705:SF0; ORIGIN RECOGNITION COMPLEX SUBUNIT 5; 1.
DR Pfam; PF13191; AAA_16; 1.
DR Pfam; PF14630; ORC5_C; 1.
DR Pfam; PF21639; ORC5_lid; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
PE 3: Inferred from homology;
KW DNA replication {ECO:0000256|ARBA:ARBA00022705};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000000267}.
FT DOMAIN 8..155
FT /note="Orc1-like AAA ATPase"
FT /evidence="ECO:0000259|Pfam:PF13191"
FT DOMAIN 237..292
FT /note="ORC5 lid"
FT /evidence="ECO:0000259|Pfam:PF21639"
FT DOMAIN 325..475
FT /note="Origin recognition complex subunit 5 C-terminal"
FT /evidence="ECO:0000259|Pfam:PF14630"
SQ SEQUENCE 480 AA; 55502 MW; 0247043F5416EECC CRC64;
MSGLLPDVPY RDYQVNAIYS FLQHDPELTF SNIVLQGATG TGKTYIMKKF FEYNPEFISV
WLHPIELVSW KPLMQAILRS TQQKLKQLYP DIEAQEYDPL DVEDPYQLLT LLESVLEEYS
KVDMKSNLII IFDGLDKLQD LDASVLFKLM KFLELLPDEY NIQLKFVYLI QDSSILDRYA
SCLLPTIVFP RYTVDEVTEI LILTRTNDLI NSDAFRNCIL TQVIDNCDDD QFCKVAMNFI
TLIIQAFHPY TGNDIDTLND LIDFKWDQYI EQITKENILD PVALYRSTSK IFISTEDNLG
DDDNDEDVGA DEENNGKEVF QTYELSTISK YLLIAAYICS YLEARYDSSV FSKKSNIKSG
RISYGRRKKK EVNPRYLAPS IFSLERLFAV FQAIYPVEFK TESGTLSSLR EDKLIKANME
VFQNLAELHS LKLVATAVTK NIDFLSPKVK WKVNVPWEII NEISESVKFD LGLYFSNLHD
//
