ID A7TFV1_VANPO Unreviewed; 323 AA.
AC A7TFV1;
DT 02-OCT-2007, integrated into UniProtKB/TrEMBL.
DT 02-OCT-2007, sequence version 1.
DT 27-MAR-2024, entry version 78.
DE RecName: Full=Homeobox domain-containing protein {ECO:0000259|PROSITE:PS50071};
GN ORFNames=Kpol_1023p80 {ECO:0000313|EMBL:EDO18909.1};
OS Vanderwaltozyma polyspora (strain ATCC 22028 / DSM 70294 / BCRC 21397 / CBS
OS 2163 / NBRC 10782 / NRRL Y-8283 / UCD 57-17) (Kluyveromyces polysporus).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Saccharomycetaceae; Vanderwaltozyma.
OX NCBI_TaxID=436907 {ECO:0000313|Proteomes:UP000000267};
RN [1] {ECO:0000313|EMBL:EDO18909.1, ECO:0000313|Proteomes:UP000000267}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 22028 / DSM 70294 / BCRC 21397 / CBS 2163 / NBRC 10782 /
RC NRRL Y-8283 / UCD 57-17 {ECO:0000313|Proteomes:UP000000267};
RX PubMed=17494770; DOI=10.1073/pnas.0608218104;
RA Scannell D.R., Frank A.C., Conant G.C., Byrne K.P., Woolfit M., Wolfe K.H.;
RT "Independent sorting-out of thousands of duplicated gene pairs in two yeast
RT species descended from a whole-genome duplication.";
RL Proc. Natl. Acad. Sci. U.S.A. 104:8397-8402(2007).
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123,
CC ECO:0000256|PROSITE-ProRule:PRU00108, ECO:0000256|RuleBase:RU000682}.
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DR EMBL; DS480384; EDO18909.1; -; Genomic_DNA.
DR RefSeq; XP_001646767.1; XM_001646717.1.
DR AlphaFoldDB; A7TFV1; -.
DR STRING; 436907.A7TFV1; -.
DR GeneID; 5547227; -.
DR KEGG; vpo:Kpol_1023p80; -.
DR eggNOG; KOG0490; Eukaryota.
DR HOGENOM; CLU_043444_0_0_1; -.
DR InParanoid; A7TFV1; -.
DR OMA; MELANKC; -.
DR OrthoDB; 912260at2759; -.
DR PhylomeDB; A7TFV1; -.
DR Proteomes; UP000000267; Unassembled WGS sequence.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0000981; F:DNA-binding transcription factor activity, RNA polymerase II-specific; IEA:InterPro.
DR CDD; cd00086; homeodomain; 1.
DR Gene3D; 1.10.10.60; Homeodomain-like; 1.
DR InterPro; IPR009057; Homeobox-like_sf.
DR InterPro; IPR017970; Homeobox_CS.
DR InterPro; IPR001356; Homeobox_dom.
DR PANTHER; PTHR24324:SF5; HEMATOPOIETICALLY-EXPRESSED HOMEOBOX PROTEIN HHEX; 1.
DR PANTHER; PTHR24324; HOMEOBOX PROTEIN HHEX; 1.
DR Pfam; PF00046; Homeodomain; 1.
DR SMART; SM00389; HOX; 1.
DR SUPFAM; SSF46689; Homeodomain-like; 1.
DR PROSITE; PS00027; HOMEOBOX_1; 1.
DR PROSITE; PS50071; HOMEOBOX_2; 1.
PE 4: Predicted;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125, ECO:0000256|PROSITE-
KW ProRule:PRU00108};
KW Homeobox {ECO:0000256|ARBA:ARBA00023155, ECO:0000256|PROSITE-
KW ProRule:PRU00108};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242, ECO:0000256|PROSITE-
KW ProRule:PRU00108}; Reference proteome {ECO:0000313|Proteomes:UP000000267}.
FT DOMAIN 156..216
FT /note="Homeobox"
FT /evidence="ECO:0000259|PROSITE:PS50071"
FT DNA_BIND 158..217
FT /note="Homeobox"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00108"
SQ SEQUENCE 323 AA; 35566 MW; CBD52115746879D5 CRC64;
MSLLPSLSIL LKATELSCIN DNTINTLQSN KIQLPPLNRD LFHSPIDPIQ RIPSIPPLIV
KNKTDVKCHN SNQKTFTSIE TLTPAATPVP LKRSHSDVSS EDVSAARNSI AKNIDIIAPS
PIRKGEPLPN SKKVFAFVTH SPDSYPKNEP KVDDEQLVRR KRRRTSSQES DILHAHFSVS
PILDKETRSK LSKLCSMSEK AVQIWFQNKR QALKRQALAK QEEEAAAAAA AAAITLPDSS
SLTQSSLQNN NQPVKGPQAL TFHINGGKGT LKAIKTSPNN RVNRLINNYR NGLGKEQNGA
PFKNHNGKTL KLAFDSTSKI SLR
//
