ID   A7TH06_VANPO            Unreviewed;       824 AA.
AC   A7TH06;
DT   02-OCT-2007, integrated into UniProtKB/TrEMBL.
DT   02-OCT-2007, sequence version 1.
DT   27-MAR-2024, entry version 82.
DE   RecName: Full=C2H2-type domain-containing protein {ECO:0000259|PROSITE:PS50157};
GN   ORFNames=Kpol_1032p52 {ECO:0000313|EMBL:EDO18458.1};
OS   Vanderwaltozyma polyspora (strain ATCC 22028 / DSM 70294 / BCRC 21397 / CBS
OS   2163 / NBRC 10782 / NRRL Y-8283 / UCD 57-17) (Kluyveromyces polysporus).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Saccharomycetaceae; Vanderwaltozyma.
OX   NCBI_TaxID=436907 {ECO:0000313|Proteomes:UP000000267};
RN   [1] {ECO:0000313|EMBL:EDO18458.1, ECO:0000313|Proteomes:UP000000267}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 22028 / DSM 70294 / BCRC 21397 / CBS 2163 / NBRC 10782 /
RC   NRRL Y-8283 / UCD 57-17 {ECO:0000313|Proteomes:UP000000267};
RX   PubMed=17494770; DOI=10.1073/pnas.0608218104;
RA   Scannell D.R., Frank A.C., Conant G.C., Byrne K.P., Woolfit M., Wolfe K.H.;
RT   "Independent sorting-out of thousands of duplicated gene pairs in two yeast
RT   species descended from a whole-genome duplication.";
RL   Proc. Natl. Acad. Sci. U.S.A. 104:8397-8402(2007).
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
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DR   EMBL; DS480389; EDO18458.1; -; Genomic_DNA.
DR   RefSeq; XP_001646316.1; XM_001646266.1.
DR   AlphaFoldDB; A7TH06; -.
DR   STRING; 436907.A7TH06; -.
DR   GeneID; 5546745; -.
DR   KEGG; vpo:Kpol_1032p52; -.
DR   eggNOG; KOG0958; Eukaryota.
DR   eggNOG; KOG1721; Eukaryota.
DR   HOGENOM; CLU_008557_0_0_1; -.
DR   InParanoid; A7TH06; -.
DR   OMA; RCAGANT; -.
DR   OrthoDB; 48111at2759; -.
DR   PhylomeDB; A7TH06; -.
DR   Proteomes; UP000000267; Unassembled WGS sequence.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   Gene3D; 3.30.160.60; Classic Zinc Finger; 2.
DR   Gene3D; 2.60.120.650; Cupin; 1.
DR   InterPro; IPR003347; JmjC_dom.
DR   InterPro; IPR036236; Znf_C2H2_sf.
DR   InterPro; IPR013087; Znf_C2H2_type.
DR   PANTHER; PTHR19818:SF139; ZINC FINGER PROTEIN ZIC 1; 1.
DR   PANTHER; PTHR19818; ZINC FINGER PROTEIN ZIC AND GLI; 1.
DR   Pfam; PF02373; JmjC; 1.
DR   Pfam; PF00096; zf-C2H2; 1.
DR   SMART; SM00355; ZnF_C2H2; 2.
DR   SUPFAM; SSF57667; beta-beta-alpha zinc fingers; 1.
DR   PROSITE; PS00028; ZINC_FINGER_C2H2_1; 1.
DR   PROSITE; PS50157; ZINC_FINGER_C2H2_2; 2.
PE   4: Predicted;
KW   Metal-binding {ECO:0000256|PROSITE-ProRule:PRU00042};
KW   Reference proteome {ECO:0000313|Proteomes:UP000000267};
KW   Zinc {ECO:0000256|PROSITE-ProRule:PRU00042};
KW   Zinc-finger {ECO:0000256|PROSITE-ProRule:PRU00042}.
FT   DOMAIN          687..715
FT                   /note="C2H2-type"
FT                   /evidence="ECO:0000259|PROSITE:PS50157"
FT   DOMAIN          716..748
FT                   /note="C2H2-type"
FT                   /evidence="ECO:0000259|PROSITE:PS50157"
FT   REGION          388..430
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          476..516
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          620..676
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          703..722
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          737..798
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        644..676
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        739..771
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        778..796
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   824 AA;  90357 MW;  8ED3F724558F4286 CRC64;
     MNSYNDDRCP VYHPDISDLL HLDDYILKTL KNLDPTDVPA IKILPPKDWS DDINHFGSDS
     NISFTLQDYS VSTNKDSSYS LSLQNYSKEV PFLELFKDYD SKNKTTSDIN DFWKRLNSKK
     YTTVKKCGVL SNPSDVHGWS FSSSKKLGKL NPIQDTLVLG SKFSFSSLPN TTGNYHLNYI
     HKGSPKCWYI VSKDNGELIQ SSDEDEDNSF VSPQIMMKKN IEFIEVTQNE NEFLLLSPNY
     KAFQIDTGLN LSELSTLSQD SLQFGNPQQS TSLSLDQDIK NKNLGELLDH SSNELSQIED
     NKLINSPLSL STYNLIQGSS IRSTSPNQSQ FFNGNQTTIS RISSPLLTRM MDLSNIVEPT
     LEDPTLKFKK RLTTSQVSSP KLINTAVLNS HDPTLSSTAQ ELQRTASNTA PNSSHAAHSN
     MTANNPTLSL LEDNDDNMLA LSLASMANSR VSSPRLTLPP LNSALDPSSI SMNLNNNSLL
     SNDNTPNMSS ISLNTSNNPN SNLNQNSSIL SPKPSYNTNP LSYQSVSSVV NKSIPGAPSS
     PTTAKLPFIK RLKSPNIVTL NISREGSKSP VSFVSDYRSP LGVTNPLTYT GASNSSLSQL
     QQLDFNTNNG NINITSSNII GNTVDTIPSP QPPAQKKPKL EKKSNQNFSS SAPTAGRKKQ
     SSNQPTPSQQ TKFASNEIII SENGKVYICQ ECKRQFSSGH HLTRHKKSVH SGEKPHSCPK
     CGKRFKRRDH VLQHLNKKIP CTQDGSSSAP VASTTSTIKS ETAQPSSSGP DIVAGSGILP
     SATTSSLQSQ PTGPIPTAVS EIPVVHDTED MTHQEQHYTM VEKI
//