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Database: UniProt
Entry: A7TPV3
LinkDB: A7TPV3
Original site: A7TPV3 
ID   SET5_VANPO              Reviewed;         499 AA.
AC   A7TPV3;
DT   18-MAR-2008, integrated into UniProtKB/Swiss-Prot.
DT   02-OCT-2007, sequence version 1.
DT   10-APR-2019, entry version 45.
DE   RecName: Full=Potential protein lysine methyltransferase SET5;
DE            EC=2.1.1.-;
DE   AltName: Full=SET domain-containing protein 5;
GN   Name=SET5; ORFNames=Kpol_1000p13;
OS   Vanderwaltozyma polyspora (strain ATCC 22028 / DSM 70294)
OS   (Kluyveromyces polysporus).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina;
OC   Saccharomycetes; Saccharomycetales; Saccharomycetaceae;
OC   Vanderwaltozyma.
OX   NCBI_TaxID=436907;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 22028 / DSM 70294;
RX   PubMed=17494770; DOI=10.1073/pnas.0608218104;
RA   Scannell D.R., Frank A.C., Conant G.C., Byrne K.P., Woolfit M.,
RA   Wolfe K.H.;
RT   "Independent sorting-out of thousands of duplicated gene pairs in two
RT   yeast species descended from a whole-genome duplication.";
RL   Proc. Natl. Acad. Sci. U.S.A. 104:8397-8402(2007).
CC   -!- FUNCTION: Putative protein lysine methyltransferase.
CC       {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250}. Nucleus
CC       {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the class V-like SAM-binding
CC       methyltransferase superfamily. Histone-lysine methyltransferase
CC       family. SET5 subfamily. {ECO:0000255|PROSITE-ProRule:PRU00190}.
DR   EMBL; DS480448; EDO15701.1; -; Genomic_DNA.
DR   RefSeq; XP_001643559.1; XM_001643509.1.
DR   ProteinModelPortal; A7TPV3; -.
DR   STRING; 36033.XP_001643559.1; -.
DR   PRIDE; A7TPV3; -.
DR   EnsemblFungi; EDO15701; EDO15701; Kpol_1000p13.
DR   GeneID; 5543809; -.
DR   KEGG; vpo:Kpol_1000p13; -.
DR   eggNOG; KOG2084; Eukaryota.
DR   eggNOG; COG2940; LUCA.
DR   InParanoid; A7TPV3; -.
DR   OMA; WSVSEKR; -.
DR   OrthoDB; 1001347at2759; -.
DR   PhylomeDB; A7TPV3; -.
DR   Proteomes; UP000000267; Unassembled WGS sequence.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0000790; C:nuclear chromatin; IEA:EnsemblFungi.
DR   GO; GO:0008757; F:S-adenosylmethionine-dependent methyltransferase activity; IEA:EnsemblFungi.
DR   GO; GO:0034968; P:histone lysine methylation; IEA:EnsemblFungi.
DR   InterPro; IPR001214; SET_dom.
DR   Pfam; PF00856; SET; 1.
DR   SMART; SM00317; SET; 1.
DR   PROSITE; PS50280; SET; 1.
PE   3: Inferred from homology;
KW   Complete proteome; Cytoplasm; Methyltransferase; Nucleus;
KW   Reference proteome; S-adenosyl-L-methionine; Transferase.
FT   CHAIN         1    499       Potential protein lysine
FT                                methyltransferase SET5.
FT                                /FTId=PRO_0000324473.
FT   DOMAIN      112    386       SET. {ECO:0000255|PROSITE-
FT                                ProRule:PRU00190}.
SQ   SEQUENCE   499 AA;  56620 MW;  964EB908CCF93862 CRC64;
     MHLKFHTLSL NDSGPLLAES SVKPSQQQIC DDILLLWREE PITDGLSVDL LYDKVMGRHP
     EWILDRTEFK NAVRNQHLDS NDERSLKVYN DFIDIPSFND DYDAIIDKKT SSNVCVKNCK
     DGHKGRGLYA LKDFVKDDLI FKESYPIVVV PSMERLTLMK MGKACSLCGG LLSHLSKHFI
     VVHSLDCDNC GGVWCSNECK NIDIGHNTLK HLHKSKINGI DSVAWGKFEK YCNDNVFVAA
     YSIGVIMALA LIDKKNTDKI RKKFNLLSSV SQGIRINESD STNIGGTFDA SSGAMSNKDP
     EPIWKTSYEL LKNAIPTTDE LDMETYLSYI GRYNINQISD QMFFLPSLIN HNCEPNVRFE
     VVSNKEIRVY ARKNISAGQE LLTNYINPLH GVKLRRRELR VNYGFLCHCD RCIKEIKRNN
     DVENENLSNS INNNGGLSVP NDSLLTRRKS SMRTARPDLS ELLKTGQEFD LDIPENLSGK
     KNRRTSVRFV NQVTLAVEE
//
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