ID A7TT19_VANPO Unreviewed; 706 AA.
AC A7TT19;
DT 02-OCT-2007, integrated into UniProtKB/TrEMBL.
DT 02-OCT-2007, sequence version 1.
DT 27-MAR-2024, entry version 54.
DE RecName: Full=Glycogen [starch] synthase {ECO:0000256|RuleBase:RU363104};
DE EC=2.4.1.11 {ECO:0000256|RuleBase:RU363104};
GN ORFNames=Kpol_295p5 {ECO:0000313|EMBL:EDO14589.1};
OS Vanderwaltozyma polyspora (strain ATCC 22028 / DSM 70294 / BCRC 21397 / CBS
OS 2163 / NBRC 10782 / NRRL Y-8283 / UCD 57-17) (Kluyveromyces polysporus).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Saccharomycetaceae; Vanderwaltozyma.
OX NCBI_TaxID=436907 {ECO:0000313|Proteomes:UP000000267};
RN [1] {ECO:0000313|EMBL:EDO14589.1, ECO:0000313|Proteomes:UP000000267}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 22028 / DSM 70294 / BCRC 21397 / CBS 2163 / NBRC 10782 /
RC NRRL Y-8283 / UCD 57-17 {ECO:0000313|Proteomes:UP000000267};
RX PubMed=17494770; DOI=10.1073/pnas.0608218104;
RA Scannell D.R., Frank A.C., Conant G.C., Byrne K.P., Woolfit M., Wolfe K.H.;
RT "Independent sorting-out of thousands of duplicated gene pairs in two yeast
RT species descended from a whole-genome duplication.";
RL Proc. Natl. Acad. Sci. U.S.A. 104:8397-8402(2007).
CC -!- FUNCTION: Transfers the glycosyl residue from UDP-Glc to the non-
CC reducing end of alpha-1,4-glucan. {ECO:0000256|RuleBase:RU363104}.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=[(1->4)-alpha-D-glucosyl](n) + UDP-alpha-D-glucose = [(1->4)-
CC alpha-D-glucosyl](n+1) + H(+) + UDP; Xref=Rhea:RHEA:18549, Rhea:RHEA-
CC COMP:9584, Rhea:RHEA-COMP:9587, ChEBI:CHEBI:15378, ChEBI:CHEBI:15444,
CC ChEBI:CHEBI:58223, ChEBI:CHEBI:58885; EC=2.4.1.11;
CC Evidence={ECO:0000256|ARBA:ARBA00043769};
CC PhysiologicalDirection=left-to-right; Xref=Rhea:RHEA:18550;
CC Evidence={ECO:0000256|ARBA:ARBA00043769};
CC -!- PATHWAY: Glycan biosynthesis; glycogen biosynthesis.
CC {ECO:0000256|ARBA:ARBA00004964, ECO:0000256|RuleBase:RU363104}.
CC -!- SIMILARITY: Belongs to the glycosyltransferase 3 family.
CC {ECO:0000256|ARBA:ARBA00010686, ECO:0000256|RuleBase:RU363104}.
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DR EMBL; DS480536; EDO14589.1; -; Genomic_DNA.
DR RefSeq; XP_001642447.1; XM_001642397.1.
DR AlphaFoldDB; A7TT19; -.
DR STRING; 436907.A7TT19; -.
DR GeneID; 5542604; -.
DR KEGG; vpo:Kpol_295p5; -.
DR eggNOG; KOG3742; Eukaryota.
DR HOGENOM; CLU_015910_1_0_1; -.
DR InParanoid; A7TT19; -.
DR OMA; RDVRNHI; -.
DR OrthoDB; 9432at2759; -.
DR PhylomeDB; A7TT19; -.
DR UniPathway; UPA00164; -.
DR Proteomes; UP000000267; Unassembled WGS sequence.
DR GO; GO:0004373; F:glycogen (starch) synthase activity; IEA:UniProtKB-EC.
DR GO; GO:0005978; P:glycogen biosynthetic process; IEA:UniProtKB-UniPathway.
DR Gene3D; 6.10.260.10; -; 1.
DR Gene3D; 3.40.50.2000; Glycogen Phosphorylase B; 2.
DR InterPro; IPR008631; Glycogen_synth.
DR PANTHER; PTHR10176:SF3; GLYCOGEN [STARCH] SYNTHASE; 1.
DR PANTHER; PTHR10176; GLYCOGEN SYNTHASE; 1.
DR Pfam; PF05693; Glycogen_syn; 1.
DR SUPFAM; SSF53756; UDP-Glycosyltransferase/glycogen phosphorylase; 2.
PE 3: Inferred from homology;
KW Glycogen biosynthesis {ECO:0000256|ARBA:ARBA00023056,
KW ECO:0000256|RuleBase:RU363104};
KW Glycosyltransferase {ECO:0000256|RuleBase:RU363104};
KW Reference proteome {ECO:0000313|Proteomes:UP000000267};
KW Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000256|RuleBase:RU363104}.
SQ SEQUENCE 706 AA; 80203 MW; 89C32322D585148F CRC64;
MGRDIQNHLL FEVATEVANR VGGIYSVLKS KAPTAVAQYG DNYTLVGPLN RSSYQSEVEE
LDINDPNTFP EDILPIKYVL ESMRARGVHF VYGRWLIEGA PRVILFELGS VGHYLNDWKG
DLWSLVGIPS PENDAETNDA ILLGYTVAWF LGELTTKDNN HAIVTHCHEW LAGVALPLCR
KRRIDVVTIF TTHATLLGRY LCASGSVDFY NNLDKFDVDH EAGKYGIYHR YCIERAAAHT
ADVFTTVSQI TALEAEHLLK RKPDGILPNG INVTKFQAVH EFQNLHALKK AKINDFVRGH
FHGCFDFDLD ETLYFFIAGR YEYKNKGADM FIEALARLNY RLKVSGSKKT VVAFIIMPAK
TNSFTVEALR SQAVVKALES SVKEVTHLIG ERIFDHAIKY PHLGITSELP TNLDDIIKPS
DKVLLKRRVL ALRRSDGQLP PIVTHNMADD SHDPILNQIR HVQLFNNASD RVKVIFHPEF
LNANNPILGL DYDEFVRGCH LGVFPSYYEP WGYTPAECTV MGVPSITTNL SGFGAYMEDL
IETDQAKDYG IYIVDRRFKN PEESVEQLVD MMEEFVKKNR RQRINQRNRT ERLSDLLDWR
RMGLEYVKAR QLALRRGYPD IFRQFTNGED VNDSNMYTMA GNKKFKIMKP ISVPGSPSES
RLRSGSVTTP TVYMTPGDLG TLQEANNADD YFMLANDQED YEDNNE
//
