ID A7UT05_ANOGA Unreviewed; 545 AA.
AC A7UT05;
DT 23-OCT-2007, integrated into UniProtKB/TrEMBL.
DT 27-JUL-2011, sequence version 2.
DT 27-MAR-2024, entry version 86.
DE SubName: Full=AGAP003572-PA {ECO:0000313|EMBL:EDO64155.2};
GN ORFNames=AgaP_AGAP003572 {ECO:0000313|EMBL:EDO64155.2};
OS Anopheles gambiae (African malaria mosquito).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Diptera; Nematocera; Culicoidea; Culicidae;
OC Anophelinae; Anopheles.
OX NCBI_TaxID=7165 {ECO:0000313|EMBL:EDO64155.2};
RN [1] {ECO:0000313|EMBL:EDO64155.2}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=PEST {ECO:0000313|EMBL:EDO64155.2};
RX PubMed=12364791; DOI=10.1126/science.1076181;
RA Holt R.A., Subramanian G.M., Halpern A., Sutton G.G., Charlab R.,
RA Nusskern D.R., Wincker P., Clark A.G., Ribeiro J.M.C., Wides R.,
RA Salzberg S.L., Loftus B.J., Yandell M.D., Majoros W.H., Rusch D.B., Lai Z.,
RA Kraft C.L., Abril J.F., Anthouard V., Arensburger P., Atkinson P.W.,
RA Baden H., de Berardinis V., Baldwin D., Benes V., Biedler J., Blass C.,
RA Bolanos R., Boscus D., Barnstead M., Cai S., Center A., Chaturverdi K.,
RA Christophides G.K., Chrystal M.A.M., Clamp M., Cravchik A., Curwen V.,
RA Dana A., Delcher A., Dew I., Evans C.A., Flanigan M.,
RA Grundschober-Freimoser A., Friedli L., Gu Z., Guan P., Guigo R.,
RA Hillenmeyer M.E., Hladun S.L., Hogan J.R., Hong Y.S., Hoover J.,
RA Jaillon O., Ke Z., Kodira C.D., Kokoza E., Koutsos A., Letunic I.,
RA Levitsky A.A., Liang Y., Lin J.-J., Lobo N.F., Lopez J.R., Malek J.A.,
RA McIntosh T.C., Meister S., Miller J.R., Mobarry C., Mongin E., Murphy S.D.,
RA O'Brochta D.A., Pfannkoch C., Qi R., Regier M.A., Remington K., Shao H.,
RA Sharakhova M.V., Sitter C.D., Shetty J., Smith T.J., Strong R., Sun J.,
RA Thomasova D., Ton L.Q., Topalis P., Tu Z.J., Unger M.F., Walenz B.,
RA Wang A.H., Wang J., Wang M., Wang X., Woodford K.J., Wortman J.R., Wu M.,
RA Yao A., Zdobnov E.M., Zhang H., Zhao Q., Zhao S., Zhu S.C., Zhimulev I.,
RA Coluzzi M., della Torre A., Roth C.W., Louis C., Kalush F., Mural R.J.,
RA Myers E.W., Adams M.D., Smith H.O., Broder S., Gardner M.J., Fraser C.M.,
RA Birney E., Bork P., Brey P.T., Venter J.C., Weissenbach J., Kafatos F.C.,
RA Collins F.H., Hoffman S.L.;
RT "The genome sequence of the malaria mosquito Anopheles gambiae.";
RL Science 298:129-149(2002).
RN [2] {ECO:0000313|EMBL:EDO64155.2}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=PEST {ECO:0000313|EMBL:EDO64155.2};
RG The Anopheles Genome Sequencing Consortium;
RL Submitted (MAR-2002) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|EMBL:EDO64155.2}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=PEST {ECO:0000313|EMBL:EDO64155.2};
RX PubMed=14747013; DOI=10.1016/j.pt.2003.11.003;
RA Mongin E., Louis C., Holt R.A., Birney E., Collins F.H.;
RT "The Anopheles gambiae genome: an update.";
RL Trends Parasitol. 20:49-52(2004).
RN [4] {ECO:0000313|EMBL:EDO64155.2}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=PEST {ECO:0000313|EMBL:EDO64155.2};
RX PubMed=17210077; DOI=10.1186/gb-2007-8-1-r5;
RA Sharakhova M.V., Hammond M.P., Lobo N.F., Krzywinski J., Unger M.F.,
RA Hillenmeyer M.E., Bruggner R.V., Birney E., Collins F.H.;
RT "Update of the Anopheles gambiae PEST genome assembly.";
RL Genome Biol. 8:R5.1-R5.13(2007).
RN [5] {ECO:0000313|EMBL:EDO64155.2}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=PEST {ECO:0000313|EMBL:EDO64155.2};
RG VectorBase;
RL Submitted (MAY-2011) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EDO64155.2}.
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DR EMBL; AAAB01008888; EDO64155.2; -; Genomic_DNA.
DR RefSeq; XP_001688433.2; XM_001688381.2.
DR AlphaFoldDB; A7UT05; -.
DR STRING; 7165.A7UT05; -.
DR PaxDb; 7165-AGAP003572-PA; -.
DR GeneID; 5667469; -.
DR KEGG; aga:AgaP_AGAP003572; -.
DR VEuPathDB; VectorBase:AGAP003572; -.
DR eggNOG; KOG4729; Eukaryota.
DR HOGENOM; CLU_019542_1_0_1; -.
DR OMA; GQRKFVE; -.
DR OrthoDB; 56324at2759; -.
DR PhylomeDB; A7UT05; -.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0030246; F:carbohydrate binding; IEA:InterPro.
DR CDD; cd22829; Gal_Rha_Lectin_EVA1_EVA1C_rpt2; 1.
DR Gene3D; 2.60.120.740; -; 2.
DR InterPro; IPR000922; Lectin_gal-bd_dom.
DR InterPro; IPR043159; Lectin_gal-bd_sf.
DR PANTHER; PTHR46780:SF25; CUB DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR46780; PROTEIN EVA-1; 1.
DR Pfam; PF02140; Gal_Lectin; 2.
DR PROSITE; PS50228; SUEL_LECTIN; 2.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 292..317
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 22..91
FT /note="SUEL-type lectin"
FT /evidence="ECO:0000259|PROSITE:PS50228"
FT DOMAIN 100..191
FT /note="SUEL-type lectin"
FT /evidence="ECO:0000259|PROSITE:PS50228"
FT REGION 230..275
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 322..345
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 521..545
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 254..271
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 545 AA; 59860 MW; 682DFA71833A7DDD CRC64;
MHPNCALLNA IPEMRKKKRN KPFHSLSHKQ CAVRPTLILF PFHSLQYSLL QTVVEACQKK
RHCKFLASPK TFGGDPCPGQ RKFVEVAYKC RPYEFRSKIA CENDVIQLIC NPYSRIAIYS
ANYGRTEYES LQCAQPQGVK EENCLASYAT ETVMQKCHGR RKCTLSADST TFGKPCRPDS
RMYLKVVYTC VPRKVLKDRF EAAPEPDEPL QSDLEQDQDE LYDEDQFFRE SDAAPPGPAP
KLQGGPTNGR VSDVPGYVGT SSSSSTPASP PRSIHDIMDD SDFSFGENQE KFYLYLIVAV
TVAILLCVSI VIGRLVVQRR RTAKDGDDKF QTSNTGETTL PNGFTDDISE IDADIDLQTP
LPVPSVSRSD SNQTCLPFTC SLHALTLPAA CTGRLFNDCR PTTNAPTRTR NDCIATRQSY
GPYTPSPGPY GNLGPSNISH TSTTMLVPPC SMGTIMSTSQ PPGYLGGPIN IMPSQLGSSI
GTIRTPLAAM TTLPRPHQPS QQLPPGFLGG SVIGTQTLRR LSSDHDGNTP RSLSRGATNA
QYYYG
//
