ID A8AAW6_IGNH4 Unreviewed; 368 AA.
AC A8AAW6;
DT 23-OCT-2007, integrated into UniProtKB/TrEMBL.
DT 23-OCT-2007, sequence version 1.
DT 27-MAR-2024, entry version 69.
DE SubName: Full=Ion transport 2 domain protein {ECO:0000313|EMBL:ABU82068.1};
GN OrderedLocusNames=Igni_0886 {ECO:0000313|EMBL:ABU82068.1};
OS Ignicoccus hospitalis (strain KIN4/I / DSM 18386 / JCM 14125).
OC Archaea; Thermoproteota; Thermoprotei; Desulfurococcales;
OC Desulfurococcaceae; Ignicoccus.
OX NCBI_TaxID=453591 {ECO:0000313|EMBL:ABU82068.1, ECO:0000313|Proteomes:UP000000262};
RN [1] {ECO:0000313|EMBL:ABU82068.1, ECO:0000313|Proteomes:UP000000262}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=KIN4/I / DSM 18386 / JCM 14125
RC {ECO:0000313|Proteomes:UP000000262};
RX PubMed=19000309; DOI=10.1186/gb-2008-9-11-r158;
RA Podar M., Anderson I., Makarova K.S., Elkins J.G., Ivanova N., Wall M.A.,
RA Lykidis A., Mavromatis K., Sun H., Hudson M.E., Chen W., Deciu C.,
RA Hutchison D., Eads J.R., Anderson A., Fernandes F., Szeto E., Lapidus A.,
RA Kyrpides N.C., Saier M.H.Jr., Richardson P.M., Rachel R., Huber H.,
RA Eisen J.A., Koonin E.V., Keller M., Stetter K.O.;
RT "A genomic analysis of the archaeal system Ignicoccus hospitalis-
RT Nanoarchaeum equitans.";
RL Genome Biol. 9:R158.1-R158.18(2008).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; CP000816; ABU82068.1; -; Genomic_DNA.
DR RefSeq; WP_012123032.1; NC_009776.1.
DR AlphaFoldDB; A8AAW6; -.
DR STRING; 453591.Igni_0886; -.
DR GeneID; 5562045; -.
DR KEGG; iho:Igni_0886; -.
DR eggNOG; arCOG01958; Archaea.
DR HOGENOM; CLU_751446_0_0_2; -.
DR OrthoDB; 43518at2157; -.
DR PhylomeDB; A8AAW6; -.
DR Proteomes; UP000000262; Chromosome.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005267; F:potassium channel activity; IEA:InterPro.
DR Gene3D; 1.10.287.70; -; 1.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR InterPro; IPR003280; 2pore_dom_K_chnl.
DR InterPro; IPR013099; K_chnl_dom.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR InterPro; IPR003148; RCK_N.
DR PANTHER; PTHR43833; POTASSIUM CHANNEL PROTEIN 2-RELATED-RELATED; 1.
DR Pfam; PF07885; Ion_trans_2; 1.
DR Pfam; PF02254; TrkA_N; 1.
DR PRINTS; PR01333; 2POREKCHANEL.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
DR SUPFAM; SSF81324; Voltage-gated potassium channels; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000000262};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT TRANSMEM 24..48
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 60..77
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 89..114
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 41..114
FT /note="Potassium channel"
FT /evidence="ECO:0000259|Pfam:PF07885"
FT DOMAIN 134..256
FT /note="RCK N-terminal"
FT /evidence="ECO:0000259|Pfam:PF02254"
SQ SEQUENCE 368 AA; 40581 MW; BFEA6F0E26EF5784 CRC64;
MKAALNWLGD KLAAWAKSLY VHTLWWYSIL FSRTSVIIAF VLITIVVISS IIFHHVEHKS
LFEAIYWAII TVTTVGYGDV VPTSFQGRLL ALALALSGFA GLTAALSIAT HFIVEKAIRE
REGELTVKGT RIMIVGSSSA CAYIATHLIR EVGKRGRIVW VTSYDTPEKY VIKAREASVV
IVKGSLTEVD TYVRGGIETA SDIVICGKND KEGLSSLAVI RSLMGKSLYP PRLIFIAHTK
RAEKLAYQEF GADVVVALDS LGYLFKESLT DPTAAMFLSA LSEEHPRLVE VNLFKKGGLL
LAKIANNVYV LGRKERLTAH ELSDALSKKR KKKIYVVAKV FGLNEVVPLR PGDYLEPHDV
AVAVEFED
//
