ID A8AE98_CITK8 Unreviewed; 478 AA.
AC A8AE98;
DT 23-OCT-2007, integrated into UniProtKB/TrEMBL.
DT 23-OCT-2007, sequence version 1.
DT 27-MAR-2024, entry version 73.
DE RecName: Full=Multidrug resistance outer membrane protein MdtQ {ECO:0008006|Google:ProtNLM};
GN OrderedLocusNames=CKO_00657 {ECO:0000313|EMBL:ABV11811.1};
OS Citrobacter koseri (strain ATCC BAA-895 / CDC 4225-83 / SGSC4696).
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
OC Enterobacteriaceae; Citrobacter.
OX NCBI_TaxID=290338 {ECO:0000313|EMBL:ABV11811.1, ECO:0000313|Proteomes:UP000008148};
RN [1] {ECO:0000313|EMBL:ABV11811.1, ECO:0000313|Proteomes:UP000008148}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC BAA-895 / CDC 4225-83 / SGSC4696
RC {ECO:0000313|Proteomes:UP000008148};
RG The Citrobacter koseri Genome Sequencing Project;
RA McClelland M., Sanderson E.K., Porwollik S., Spieth J., Clifton W.S.,
RA Latreille P., Courtney L., Wang C., Pepin K., Bhonagiri V., Nash W.,
RA Johnson M., Thiruvilangam P., Wilson R.;
RL Submitted (AUG-2007) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Could be involved in resistance to puromycin, acriflavine and
CC tetraphenylarsonium chloride. {ECO:0000256|ARBA:ARBA00037313}.
CC -!- SUBCELLULAR LOCATION: Cell outer membrane
CC {ECO:0000256|ARBA:ARBA00004459, ECO:0000256|RuleBase:RU362097}; Lipid-
CC anchor {ECO:0000256|ARBA:ARBA00004459, ECO:0000256|RuleBase:RU362097}.
CC Membrane {ECO:0000256|ARBA:ARBA00004635}; Lipid-anchor
CC {ECO:0000256|ARBA:ARBA00004635}.
CC -!- SIMILARITY: Belongs to the outer membrane factor (OMF) (TC 1.B.17)
CC family. {ECO:0000256|ARBA:ARBA00007613, ECO:0000256|RuleBase:RU362097}.
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DR EMBL; CP000822; ABV11811.1; -; Genomic_DNA.
DR RefSeq; WP_012131635.1; NC_009792.1.
DR AlphaFoldDB; A8AE98; -.
DR STRING; 290338.CKO_00657; -.
DR GeneID; 45134876; -.
DR KEGG; cko:CKO_00657; -.
DR HOGENOM; CLU_012817_6_3_6; -.
DR OrthoDB; 9770517at2; -.
DR Proteomes; UP000008148; Chromosome.
DR GO; GO:0009279; C:cell outer membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0015562; F:efflux transmembrane transporter activity; IEA:InterPro.
DR Gene3D; 1.20.1600.10; Outer membrane efflux proteins (OEP); 1.
DR Gene3D; 2.20.200.10; Outer membrane efflux proteins (OEP); 1.
DR InterPro; IPR003423; OMP_efflux.
DR InterPro; IPR010131; RND_efflux_OM_lipoprot_NodT.
DR NCBIfam; TIGR01845; outer_NodT; 1.
DR PANTHER; PTHR30203:SF20; MULTIDRUG RESISTANCE OUTER MEMBRANE PROTEIN MDTP-RELATED; 1.
DR PANTHER; PTHR30203; OUTER MEMBRANE CATION EFFLUX PROTEIN; 1.
DR Pfam; PF02321; OEP; 2.
DR SUPFAM; SSF56954; Outer membrane efflux proteins (OEP); 1.
DR PROSITE; PS51257; PROKAR_LIPOPROTEIN; 1.
PE 3: Inferred from homology;
KW Lipoprotein {ECO:0000256|ARBA:ARBA00023288, ECO:0000256|RuleBase:RU362097};
KW Membrane {ECO:0000256|RuleBase:RU362097};
KW Palmitate {ECO:0000256|ARBA:ARBA00023139, ECO:0000256|RuleBase:RU362097};
KW Reference proteome {ECO:0000313|Proteomes:UP000008148};
KW Signal {ECO:0000256|RuleBase:RU362097};
KW Transmembrane {ECO:0000256|RuleBase:RU362097};
KW Transmembrane beta strand {ECO:0000256|ARBA:ARBA00022452,
KW ECO:0000256|RuleBase:RU362097}.
FT SIGNAL 1..20
FT /evidence="ECO:0000256|RuleBase:RU362097"
FT CHAIN 21..478
FT /note="Multidrug resistance outer membrane protein MdtQ"
FT /evidence="ECO:0000256|RuleBase:RU362097"
FT /id="PRO_5001436671"
SQ SEQUENCE 478 AA; 51895 MW; D7E074C7BBEEEDE6 CRC64;
MNRDSLLATT VCLSLFTLLA GCAPMHDTRQ SLTRQTPAAQ VDSPLPTAIK SGWPDSQWWK
AYHDPQLDAL IDNALQHSPD MQVAEQRIQL AEAQAKAVEA QDGPRLDFSA DVERQKMSAE
GLMGPFAITD PAAGTTGPWY TNGTFGLTAG WDLDLWGKNR AEVSARIGVV KAREAEQAQT
RQLLASGVAR LYWEWQTQAA LKAVLTQIEH EQQNVITVDR QLYQNGITSS VEGVETDIDA
GKTQQQLNDV AGKMKIIEAR LSALTNAQSA SLTLHTVALP VTESQLPAQL SYELLARRPD
LQAAHWYIES SLGSVDAAKA AFYPDINLMA FLQQDALHLS DLFRHSAQQM GVTAGLTLPI
FDSGRLNASL DIAKAQSNLS VANYNKAVVD AVNDVARAAS QVETVAEKNQ HQRQIEHDAQ
RVVGLAQARF NAGIIAGSRV SQAKIPALRE HCNGLILQGQ WLDASIQLTS ALGGGYHL
//
