ID A8AL19_CITK8 Unreviewed; 279 AA.
AC A8AL19;
DT 23-OCT-2007, integrated into UniProtKB/TrEMBL.
DT 23-OCT-2007, sequence version 1.
DT 27-MAR-2024, entry version 82.
DE RecName: Full=Dihydrodipicolinate synthase family protein {ECO:0008006|Google:ProtNLM};
GN OrderedLocusNames=CKO_03091 {ECO:0000313|EMBL:ABV14182.1};
OS Citrobacter koseri (strain ATCC BAA-895 / CDC 4225-83 / SGSC4696).
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
OC Enterobacteriaceae; Citrobacter.
OX NCBI_TaxID=290338 {ECO:0000313|EMBL:ABV14182.1, ECO:0000313|Proteomes:UP000008148};
RN [1] {ECO:0000313|EMBL:ABV14182.1, ECO:0000313|Proteomes:UP000008148}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC BAA-895 / CDC 4225-83 / SGSC4696
RC {ECO:0000313|Proteomes:UP000008148};
RG The Citrobacter koseri Genome Sequencing Project;
RA McClelland M., Sanderson E.K., Porwollik S., Spieth J., Clifton W.S.,
RA Latreille P., Courtney L., Wang C., Pepin K., Bhonagiri V., Nash W.,
RA Johnson M., Thiruvilangam P., Wilson R.;
RL Submitted (AUG-2007) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the DapA family.
CC {ECO:0000256|PIRNR:PIRNR001365}.
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DR EMBL; CP000822; ABV14182.1; -; Genomic_DNA.
DR AlphaFoldDB; A8AL19; -.
DR STRING; 290338.CKO_03091; -.
DR KEGG; cko:CKO_03091; -.
DR HOGENOM; CLU_049343_5_1_6; -.
DR Proteomes; UP000008148; Chromosome.
DR GO; GO:0016829; F:lyase activity; IEA:UniProtKB-KW.
DR CDD; cd00408; DHDPS-like; 1.
DR Gene3D; 3.20.20.70; Aldolase class I; 1.
DR InterPro; IPR013785; Aldolase_TIM.
DR InterPro; IPR002220; DapA-like.
DR InterPro; IPR020625; Schiff_base-form_aldolases_AS.
DR PANTHER; PTHR12128:SF72; 4-HYDROXY-2-OXOGLUTARATE ALDOLASE, MITOCHONDRIAL; 1.
DR PANTHER; PTHR12128; DIHYDRODIPICOLINATE SYNTHASE; 1.
DR Pfam; PF00701; DHDPS; 1.
DR PIRSF; PIRSF001365; DHDPS; 1.
DR PRINTS; PR00146; DHPICSNTHASE.
DR SMART; SM01130; DHDPS; 1.
DR SUPFAM; SSF51569; Aldolase; 1.
DR PROSITE; PS00666; DHDPS_2; 1.
PE 3: Inferred from homology;
KW Lyase {ECO:0000256|ARBA:ARBA00023239, ECO:0000256|PIRNR:PIRNR001365};
KW Reference proteome {ECO:0000313|Proteomes:UP000008148};
KW Schiff base {ECO:0000256|ARBA:ARBA00023270}.
FT ACT_SITE 119
FT /note="Proton donor/acceptor"
FT /evidence="ECO:0000256|PIRSR:PIRSR001365-1"
FT ACT_SITE 148
FT /note="Schiff-base intermediate with substrate"
FT /evidence="ECO:0000256|PIRSR:PIRSR001365-1"
FT BINDING 193
FT /ligand="pyruvate"
FT /ligand_id="ChEBI:CHEBI:15361"
FT /evidence="ECO:0000256|PIRSR:PIRSR001365-2"
SQ SEQUENCE 279 AA; 30918 MW; D55D6CD01B3651D8 CRC64;
MDNDGKVDLN GLSQHLKRLT EANIDVILLM GSIGEFASFT LEERLMLIRE ARAMSSLKMV
ANVSSTCTGD ILLMAQEAYR VGYDAVMILP PYYYGQTSKQ LLSYFRQLGN ALSGKWFAYN
FPARTGCDLT PDLVATLAAE FPNFAGIKDT VDCQSHTRSM IQTTRAVRDD FAVLSGYDEY
YIPNLLAGGA GIISGLNNVM PELFVSAREA FKQGDLQTLR DIQEKIGTFM SIYAIGEDFV
TTIKTVVSRK FGYCTGVSRN AGGELNEHER RTIDEVFGR
//
